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T2527Ulipristal acetate醋酸乌利司他；CDB-2914；Ulipristal
Ulipristal Acetate is an orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereby inhibiting PR-mediated gene expression, and
价 格：￥电议型 号：T2527产 地：中国大陆
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T2510GalunisertibLY2157299
Galunisertib is an orally available inhibitor of TGFβRI kinase (IC50: 56 nM) with potential antineoplastic activity.
价 格：￥电议型 号：T2510产 地：中国大陆
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T2504Pritelivir普瑞利韦；BAY 57-1293；AIC316
Pritelivir (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).
价 格：￥电议型 号：T2504产 地：中国大陆
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T2499Torcetrapib托彻普；CP-529414
Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to excess deaths.
价 格：￥电议型 号：T2499产 地：中国大陆
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T2490OsimertinibMereletinib；AZD-9291；奥希替尼
Osimertinib is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC).
价 格：￥电议型 号：T2490产 地：中国大陆
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T2483Dacomitinib达克替尼；PF-299804；PF299；PF-00299804
Dacomitinib(PF299804; PF-00299804) is a highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively.
价 格：￥电议型 号：T2483产 地：中国大陆
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T2463ML141CID-2950007
ML141 is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).
价 格：￥电议型 号：T2463产 地：中国大陆
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T2433NU 7026DNA-PK Inhibitor II；LY293646；NU7026
NU7026 is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition against both ATM and ATR.
价 格：￥电议型 号：T2433产 地：中国大陆
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T2429Olverembatinib dimesylateHQP1351；GZD824 Dimesylate
GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).
价 格：￥电议型 号：T2429产 地：中国大陆
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T2422PNU-282987PNU 282987
PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).
价 格：￥电议型 号：T2422产 地：中国大陆
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T24109GSK329GSK 329；GSK-329
GSK329 is a moderately selective TNNI3K inhibitor.
价 格：￥电议型 号：T24109产 地：中国大陆
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T24030Entacapone acidAG 1290；AG1290；AG-1290；恩他卡朋酸
Entacapone is a selective and reversible inhibitor of catechol-O-methyltransferase(COMT).
价 格：￥电议型 号：T24030产 地：中国大陆
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T23515VU-29VU 29
VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes (EC50: rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM).
价 格：￥电议型 号：T23515产 地：中国大陆
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T2303Afatinib阿法替尼；BIBW2992
Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, EGFR (L858R), EGFR (L858R/T790M), HER2, and HER4, respectively.
价 格：￥电议型 号：T2303产 地：中国大陆
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T22996ML-191
ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.
价 格：￥电议型 号：T22996产 地：中国大陆
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T22994ML 154
ML 154 is a potent neuropeptide S receptor (NPSR) antagonist.
价 格：￥电议型 号：T22994产 地：中国大陆
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T22991ML-099
ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.
价 格：￥电议型 号：T22991产 地：中国大陆
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T22990ML-090
ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).
价 格：￥电议型 号：T22990产 地：中国大陆
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T2299BMS-833923XL-139；BMS833923；BMS 833923
BMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
价 格：￥电议型 号：T2299产 地：中国大陆
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T22988MK-4827 RacemateNiraparib Racemate；2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide
MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
价 格：￥电议型 号：T22988产 地：中国大陆
