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T16112ML67-33化合物 T16112ML-67-33|||ML6733|||ML67 33
ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels.
价 格:¥电议型 号:T16112产 地:中国大陆
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T16110ML418;化合物ML418ML418
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
价 格:¥电议型 号:T16110产 地:中国大陆
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T16109ML402;化合物ML402ZINC3671497|||N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide;ZINC3671497
ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.
价 格:¥电议型 号:T16109产 地:中国大陆
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T16107ML230;化合物 T16107CID44640177|||SID 88095709;CID44640177|||SID 88095709
ML230 is a selective ATP-binding cassette (ABC) transporter ABCG2 inhibitor. It 36-fold selective for ABCG2 over ABCB1 (EC50s: 0.13 μM and 4.65 μM, respectively).
价 格:¥电议型 号:T16107产 地:中国大陆
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T16106ML224;化合物ML224NCGC00242364|||ANTAG3;NCGC00242364|||ANTAG3
ML224 (NCGC00242364) is a TSHR antagonist for the treatment of Graves´ orbital disease and Graves´ hyperthyroidism.
价 格:¥电议型 号:T16106产 地:中国大陆
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T16105ML132;化合物 T16105NCGC 00185682;NCGC 00185682
ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).
价 格:¥电议型 号:T16105产 地:中国大陆
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T16104ML-9;ML-9盐酸盐ML-9
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
价 格:¥电议型 号:T16104产 地:中国大陆
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T16103ML-9 Free Base;化合物 T16103ML-9 Free Base
ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 (free base) causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
价 格:¥电议型 号:T16103产 地:中国大陆
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T16102ML-792;化合物ML792ML-792
ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. Compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 μM and >100 μM, respectively), ML-792 is an effective and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50s of 3 and 11 nM, respectively).
价 格:¥电议型 号:T16102产 地:中国大陆
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T16101ML-290;化合物ML-290ML-290
ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.
价 格:¥电议型 号:T16101产 地:中国大陆
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T16012Marizomib;马里佐米NPI-0052|||Salinosporamide A|||ML858;NPI-0052|||Salinosporamide A|||ML858
Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM, respectively.
价 格:¥电议型 号:T16012产 地:中国大陆
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T15591Ipenoxazone;伊培沙宗NC-1200|||MLV-6976;NC-1200|||MLV-6976|||伊培沙宗
Ipenoxazone is an effective and centrally acting muscle relaxant.
价 格:¥电议型 号:T15591产 地:中国大陆
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T1545Levamlodipine;左旋氨氯地平(S)-Amlodipine|||S-amlodipine;左旋氨氯地平|||(S)-Amlodipine|||S-amlodipine
Levamlodipine (S-amlodipine) belongs to the dihydropyridine group of calcium channel blockers. Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. The names S-amlodipine and levamlodipine may be used interchangeably as both substances are the same, however, with differing nomenclature. As a racemic mixture, amlodipine contains (R) and (S)-amlodipine isomers, but only (S)-amlodipine as the active moiet
价 格:¥电议型 号:T1545产 地:中国大陆
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T15216EML 425;化合物EML 425EML 425
EML 425 is a potent and selective inhibitor of CREB binding protein (CBP)/p300 (IC50s: 2.9 and 1.1 μM, respectively).
价 格:¥电议型 号:T15216产 地:中国大陆
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T14967Cimlanod;化合物 T14967BMS-986231|||CXL-1427;BMS-986231|||CXL-1427
Cimlanod is a second-generation Nitroxyl (HNO) donor for heart failure with positive lusitropic and inotropic as well as vasodilatory effects. Cimlanod delivers HNO via pH-dependent chemical breakdown when exposed to the neutral pH environment of the bloodstream.
价 格:¥电议型 号:T14967产 地:中国大陆
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T1385Amlodipine;氨氯地平UK-48340;氨氯地平|||UK-48340
Amlodipine (UK-48340) is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
价 格:¥电议型 号:T1385产 地:中国大陆
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T13774ML390;化合物ML390ML390
ML390 exerts its potent differentiation effect on multiple leukemia models.
价 格:¥电议型 号:T13774产 地:中国大陆
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T12886SGC-iMLLT;化合物SGC-IMLLTSGC-iMLLT
SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular target engagement of MLLT1(Kd = 0.129?μM) and MLLT3(Kd = 0.077?μM).
价 格:¥电议型 号:T12886产 地:中国大陆
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T124286Symlandine;化合物 SymlandineSymlandine
Symlandine is a useful organic compound for research related to life sciences and the catalog number is T124286.
价 格:¥电议型 号:T124286产 地:中国大陆
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T12080MLS000544460;化合物MLS000544460MLS000544460
MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor (Kd: 2.0 μM, IC50: 4 μM).MLS000544460 exhibits inhibitory effects on Eya2 phosphatase-mediated cell migration and has anticancer activity.
价 格:¥电议型 号:T12080产 地:中国大陆