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  • T75157LCimdelirsen sodium；化合物 Cimdelirsen sodiumCimdelirsen sodium

    Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

    价 格：￥电议型 号：T75157L产 地：中国大陆

  • T75157Cimdelirsen；化合物 CimdelirsenCimdelirsen

    Cimdelirsen, a novel ligand-conjugated, hepatic-targeted antisense oligonucleotide under investigation, aims to diminish growth hormone receptor (GHr) synthesis. This inhibits the harmful effects of growth hormone (GH) hypersecretion and lowers circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

    价 格：￥电议型 号：T75157产 地：中国大陆

  • T75151Aganirsen；化合物 AganirsenAganirsen

    Aganirsen, a 25-mer DNA antisense oligonucleotide, silences the expression of insulin receptor substrate-1 (IRS-1).

    价 格：￥电议型 号：T75151产 地：中国大陆

  • T74948LSARS-CoV-2-IN-30 disodium；化合物 SARS-CoV-2-IN-30 disodiumSARS-CoV-2-IN-30 disodium

    SARS-CoV-2-IN-30 disodium, a benzene-system-based two-armed diphosphate ester featuring molecular tweezers, demonstrates antiviral efficacy, with IC50 values of 0.6 μM against SARS-CoV-2 and 6.9 μM for spike pseudoparticle transduction, respectively. Additionally, it disrupts liposomal membranes, evidenced by an EC50 of 6.9 μM [1].

    价 格：￥电议型 号：T74948L产 地：中国大陆

  • T74948SARS-CoV-2-IN-30；化合物 SARS-CoV-2-IN-30SARS-CoV-2-IN-30

    SARS-CoV-2-IN-30, a two-armed diphosphate ester featuring a benzene system and molecular tweezers, demonstrates antiviral properties, achieving IC50 values of 0.6 μM against SARS-CoV-2 activity and 6.9 μM for spike pseudoparticle transduction. Additionally, it disrupts liposomal membranes with an EC50 of 6.9 μM [1].

    价 格：￥电议型 号：T74948产 地：中国大陆

  • T74947LSARS-CoV-2-IN-29 disodium；化合物 SARS-CoV-2-IN-29 disodiumSARS-CoV-2-IN-29 disodium

    SARS-CoV-2-IN-29 disodium, a diphosphate ester featuring a benzene system and molecular tweezers architecture, demonstrates antiviral efficacy by targeting SARS-CoV-2 with half-maximal inhibitory concentrations (IC50s) of 1.5 μM for virus activity and 1.6 μM for spike pseudoparticle transduction. Additionally, it disrupts liposomal membranes, evidenced by a half-maximal effective concentration (EC50) of 3.0 μM [1].

    价 格：￥电议型 号：T74947L产 地：中国大陆

  • T74947SARS-CoV-2-IN-29；化合物 SARS-CoV-2-IN-29SARS-CoV-2-IN-29

    SARS-CoV-2-IN-29, a two-armed diphosphate ester featuring a benzene system and molecular tweezers, demonstrates antiviral efficacy with IC50 values of 1.5 μM for SARS-CoV-2 activity and 1.6 μM against spike pseudoparticle transduction. Additionally, it disrupts liposomal membranes, as indicated by an EC50 of 3.0 μM [1].

    价 格：￥电议型 号：T74947产 地：中国大陆

  • T74946LSARS-CoV-2-IN-28 disodium；化合物 SARS-CoV-2-IN-28 disodiumSARS-CoV-2-IN-28 disodium

    SARS-CoV-2-IN-28 disodium, a diphosphate ester featuring a C7 alkyl chain and extended-length molecular tweezers, demonstrates antiviral efficacy by showing IC50 values of 0.4 μM and 1.0 μM against SARS-CoV-2 activity and spike pseudoparticle transduction, respectively. Additionally, it disrupts liposomal membranes with an EC50 of 4.4 μM [1].

    价 格：￥电议型 号：T74946L产 地：中国大陆

  • T74946SARS-CoV-2-IN-28；化合物 SARS-CoV-2-IN-28SARS-CoV-2-IN-28

    SARS-CoV-2-IN-28, a two-armed diphosphate ester featuring a C7 alkyl chain and molecular tweezers of extended length, demonstrates antiviral properties by exhibiting IC 50 values of 0.4 μM against SARS-CoV-2 activity and 1.0 μM against spike pseudoparticle transduction. Additionally, it disrupts liposomal membranes, evidenced by an EC 50 value of 4.4 μM [1].

    价 格：￥电议型 号：T74946产 地：中国大陆

  • T74945LSARS-CoV-2-IN-27 disodium；化合物 SARS-CoV-2-IN-27 disodiumSARS-CoV-2-IN-27 disodium

    SARS-CoV-2-IN-27 disodium, a diphosphate ester featuring a C6 alkyl chain and molecular tweezers of extended length, demonstrates antiviral efficacy by achieving IC50 values of 1.0 μM against SARS-CoV-2 activity and 1.7 μM for spike pseudoparticle transduction. Additionally, it disrupts liposomal membranes, displaying an EC50 value of 6.5 μM [1].

    价 格：￥电议型 号：T74945L产 地：中国大陆

  • T74945SARS-CoV-2-IN-27；化合物 SARS-CoV-2-IN-27SARS-CoV-2-IN-27

    SARS-CoV-2-IN-27, a diphosphate ester featuring a C6 alkyl chain and extended-length molecular tweezers, demonstrates antiviral efficacy, with IC50 values of 1.0 μM and 1.7 μM against SARS-CoV-2 activity and spike pseudoparticle transduction, respectively. Additionally, it disrupts liposomal membranes, evidenced by an EC50 of 6.5 μM [1].

    价 格：￥电议型 号：T74945产 地：中国大陆

  • T74944LSARS-CoV-2-IN-23 disodium；化合物 SARS-CoV-2-IN-23 disodiumSARS-CoV-2-IN-23 disodium

    SARS-CoV-2-IN-23 disodium, a medium-length molecular tweezer and two-armed diphosphate ester, demonstrates antiviral properties by inhibiting SARS-CoV-2 activity and spike pseudoparticle transduction with IC50 values of 8.2 μM and 2.6 μM, respectively. Additionally, it disrupts liposomal membranes with an EC50 of 4.4 μM [1].

    价 格：￥电议型 号：T74944L产 地：中国大陆

  • T74944SARS-CoV-2-IN-26；化合物 SARS-CoV-2-IN-26SARS-CoV-2-IN-26

    SARS-CoV-2-IN-23, a two-armed diphosphate ester and medium-length molecular tweezers, displays antiviral properties, demonstrating IC50 values of 8.2 μM against SARS-CoV-2 activity and 2.6 μM for spike pseudoparticle transduction. Additionally, it induces liposomal membrane disruption with an EC50 value of 4.4 μM [1].

    价 格：￥电议型 号：T74944产 地：中国大陆

  • T74943LSARS-CoV-2-IN-25 disodium；化合物 SARS-CoV-2-IN-25 disodiumSARS-CoV-2-IN-25 disodium

    SARS-CoV-2-IN-25 (Compound CP026) disodium, a potent inhibitor of SARS-CoV-2 spike pseudoparticle transduction, demonstrates significant efficacy with an IC50 value of 1.6 μM. Additionally, it effectively inhibits enveloped viruses and liposomes, showcasing its broad-spectrum antiviral potential.

    价 格：￥电议型 号：T74943L产 地：中国大陆

  • T74943SARS-CoV-2-IN-25；化合物 SARS-CoV-2-IN-25SARS-CoV-2-IN-25

    SARS-CoV-2-IN-25 (Compound CP026) is a potent inhibitor, specifically targeting the transduction of SARS-CoV-2 spike pseudoparticles, with an inhibitory concentration (IC50) of 1.6 μM. It effectively inhibits enveloped viruses and liposomes [1].

    价 格：￥电议型 号：T74943产 地：中国大陆

  • T74881FITC-labeled Tominersen；化合物 FITC-labeled TominersenFITC-labeled Tominersen

    FITC-labeled Tominersen is Tominersen labeled with FITC. Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces brain atrophy in mice. Tominersen can be used for the research of Huntington’s disease (HD).

    价 格：￥电议型 号：T74881产 地：中国大陆

  • T74842Trecovirsen；化合物 TrecovirsenTrecovirsen

    Trecovirsen (GEM91) is a 25-mer antisense phosphorothioate oligonucleotide that targets the gag site of the HIV gene.

    价 格：￥电议型 号：T74842产 地：中国大陆

  • T74810Anti-MRSA agent 7；化合物 Anti-MRSA agent 7Anti-MRSA agent 7

    Anti-MRSA agent 7 (Compound 12) serves as a potent antibacterial compound effectively inhibiting both S. aureus and E. coli DNA gyrases, as well as topo IV enzymes from the same organisms, with IC50 values of 0.185 μM, 0.365 μM, 0.341 μM, and 0.059 μM, respectively [1].

    价 格：￥电议型 号：T74810产 地：中国大陆

  • T74807SARS-CoV-2 3CLpro-IN-13；化合物 SARS-CoV-2 3CLpro-IN-13SARS-CoV-2 3CLpro-IN-13

    SARS-CoV-2 3CLpro-IN-13 is a potent inhibitor of the SARS-CoV-2 3CL protease, demonstrating significant anti-coronavirus activity with an IC50 value of 21 nM [1].

    价 格：￥电议型 号：T74807产 地：中国大陆

  • T74720Mipomersen；化合物 MipomersenMipomersen

    Mipomersen (ISIS 301012 free base), an antisense oligonucleotide inhibitor of apolipoprotein B (apoB), exhibits an anti-HCV effect and reduces the infectivity of HCV. It is used in research targeting homozygous familial hypercholesterolemia (HoFH) [1] [2].

    价 格：￥电议型 号：T74720产 地：中国大陆

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