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T15032CYM50308;化合物CYM50308CYM50308
CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM). CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM and it shows 37-fold more selective for S1P4-R than S1P5-R.
价 格:¥电议型 号:T15032产 地:中国大陆
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T15031CYM50260;化合物CYM50260CYM50260
CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.
价 格:¥电议型 号:T15031产 地:中国大陆
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T15030CycLuc1;化合物CycLuc1u00A0CycLuc1
CycLuc1 is a brain penetrant luciferase substrate. CycLuc1 may be a superior BLI substrate as compared to D-luciferin for monitoring tumor growth of intracranial GBM xenografts.
价 格:¥电议型 号:T15030产 地:中国大陆
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T15029Cyclopyrimorate;化合物 T15029Cyclopyrimorate
Cyclopyrimorate is a highly effective bleaching herbicide for weed control in rice fields.
价 格:¥电议型 号:T15029产 地:中国大陆
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T15028Cyclopropavir;化合物 T15028MBX-400|||Filociclovir|||ZSM-I-62;MBX-400|||Filociclovir|||ZSM-I-62
Cyclopropavir (Filociclovir; MBX-400) is a compound of broad-spectrum anti-herpesvirus. It has good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8 (EC50s: 0.7 μM to 8 μM).
价 格:¥电议型 号:T15028产 地:中国大陆
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T15027Cyclopiazonic acid环二氮酸环匹阿尼酸|||环二氮酸
Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A. flavus. Cyclopiazonic acid (CPA) is an endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA)nanomolar inhibitor and a potent inducer of cell death in plants.
价 格:¥电议型 号:T15027产 地:中国大陆
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T15026Cyamemazine;化合物 T15026Cyamemazine
Cyamemazine, contains the phenothiazine chromophore, is a neuroleptic agent used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki: 12 nM), 5-HT2A (Ki: 1.5 nM) and 5-HT2C (Ki: 75 nM) receptors antagonist with antipsychotic activity.
价 格:¥电议型 号:T15026产 地:中国大陆
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T15025LCY5 triethylamine saltCY5三乙胺盐CY5 triethylamine salt(146368-11-8 Free base)
CY5 triethylamine salt is a water-soluble dye, Excitation (nm):649, Emission (nm): 670.
价 格:¥电议型 号:T15025L产 地:中国大陆
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T15025CY5;磺酸基-Cy5羧酸Sulfo-Cyanine5;Sulfo-Cyanine5
Cy5 (Sulfo-Cyanine5) is a phalloidin dye used to label amino groups in peptides, proteins and oligonucleotides.
价 格:¥电议型 号:T15025产 地:中国大陆
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T15024Silmitasertib sodium salt;化合物Silmitasertib sodium saltCX-4945 sodium salt;CX-4945 sodium salt
Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).
价 格:¥电议型 号:T15024产 地:中国大陆
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T15023CX-157;化合物 CX-157KP 157;KP 157
CX-157 (KP 157) is a novel monoamine oxidase-A (MAO-A) inhibitor for the study of depression-like neurological disorders and cancer.
价 格:¥电议型 号:T15023产 地:中国大陆
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T15022CVT-10216化合物CVT-102163-[[[3-[4-[(甲基磺酰基)氨基]苯基]-4-氧代-4H-苯并吡喃-7-基]氧基]甲基]苯甲酸
CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50: 29 nM). CVT-10216 also has inhibitory effect of ALDH-1 (IC50: 1.3 μM). CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects.
价 格:¥电议型 号:T15022产 地:中国大陆
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T15021CV-159;化合物 T15021CV-159
CV-159 is a unique dihydropyridine Ca2+ antagonist with antiinflammatory activities. It has an anti-calmodulin (CaM) action.
价 格:¥电议型 号:T15021产 地:中国大陆
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T15020CU-CPT22;化合物CU-CPT22CU-CPT22
CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 binds at the interface of TLR1 and TLR2 (IC50 = 0.58 μM). It competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 (Ki: 0.41 μM).
价 格:¥电议型 号:T15020产 地:中国大陆
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T1502Vildagliptin维格列汀维达列汀|||NVP-LAF 237|||维格列汀|||LAF237
Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin´s cyano moiety undergoes hydrolysis and this inactive metabolite is excreted mainly via the urine.
价 格:¥电议型 号:T1502产 地:中国大陆
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T15019LCUR61414 hydrochloride;化合物CUR61414 hydrochlorideCUR61414 hydrochloride (334998-36-6 Free base);CU
CUR61414 hydrochloride is a potent and cell permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM). CUR61414 hydrochloride is a small-molecule aminoproline class compound. CUR61414 hydrochloride selectively binds to smoothened (Smo, Ki= 44 nM). CUR61414 hydrochloride can induce cancer cells apoptosis without affecting neighboring non-tumor cells.
价 格:¥电议型 号:T15019L产 地:中国大陆
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T15019CUR61414;化合物CUR61414CUR61414
CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50?=100-200 nM) and selectively binds to smoothened (Ki = 44 nM).
价 格:¥电议型 号:T15019产 地:中国大陆
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T15018CUDC-427;化合物CUDC-427GDC-0917;GDC-0917
CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.
价 格:¥电议型 号:T15018产 地:中国大陆
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T15017CU-T12-9;化合物CU-T12-9CU-T12-9
CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS.
价 格:¥电议型 号:T15017产 地:中国大陆
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T15016CTX1化合物 T15016CTX-1|||CTX1
CTX1 is a small molecule activator of p53.
价 格:¥电议型 号:T15016产 地:中国大陆