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T10560P2X3 antagonist 34；化合物 T10560BLU-5937；BLU-5937
P2X3 antagonist 34, a potent, selective, and orally active antagonist, targets the P2X3 homotrimeric receptor, exhibiting IC50s of 25 nM, 92 nM, and 126 nM for human, rat, and guinea pig P2X3 receptors respectively. It shows reduced activity against P2X2/3 heterotrimeric receptors across human, rat, and guinea pig models. Notably, this compound demonstrates a significant anti-tussive effect without altering taste[1].
价 格：￥电议型 号：T10560产 地：中国大陆
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T10552Bitopertin (R enantiomer)；化合物 T10552RO4917838 (R enantiomer)|||RG1678 (R enantiomer)|||Bitopertin R
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM).
价 格：￥电议型 号：T10552产 地：中国大陆
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T10524β-Cryptoxanthin；化合物 T10524(3R)-β-Cryptoxanthin；(3R)-β-Cryptoxanthin
β-Cryptoxanthin is isolated from Satsuma mandarin orange with an anti-stress effect. It is an oxygenated carotenoid and an antioxidant.
价 格：￥电议型 号：T10524产 地：中国大陆
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T10517BET-BAY 002 (S enantiomer)；化合物 T10517BET-BAY 002 (S enantiomer)
The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).
价 格：￥电议型 号：T10517产 地：中国大陆
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T10515Anti-Heart Failure Agent 1；化合物 T10515Anti-Heart Failure Agent 1
Anti-Heart Failure Agent 1 is an orally available compound suitable for the treatment of heart failure without inducing vomiting, nausea, and restlessness.
价 格：￥电议型 号：T10515产 地：中国大陆
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T10511Anti-hypertensive sulfonanilide 1；化合物 T10511Anti-hypertensive sulfonanilide 1
Anti-hypertensive sulfonanilide 1 is an antihypertensive compound.
价 格：￥电议型 号：T10511产 地：中国大陆
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T10510CB1 antagonist 1；化合物 T10510CB1 antagonist 1
CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, and gastrointestinal disorders, psychosis, and cardiovascular.
价 格：￥电议型 号：T10510产 地：中国大陆
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T10509Xanthine oxidase-IN-1；黄嘌呤氧化酶IN14-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid；4-(3-Cyano-5
Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid and nucleotide intermediates.
价 格：￥电议型 号：T10509产 地：中国大陆
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T10500Antibacterial compound 1；化合物 T10500Antibacterial compound 1
Antibacterial compound 1 is an antibacterial compound.
价 格：￥电议型 号：T10500产 地：中国大陆
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T104985-HT2A antagonist 1；化合物 T104985-HT2A antagonist 1
5-HT2A antagonist 1 is a 5-HT2A antagonist. It may be useful in the treatment of gastrointestinal disorders circulatory disorders.
价 格：￥电议型 号：T10498产 地：中国大陆
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T10480Bay 41-4109 (less active enantiomer)；化合物 T10480Bay 41-4109 (less active enantiomer)
Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).
价 格：￥电议型 号：T10480产 地：中国大陆
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T10465Atuveciclib S-Enantiomer；化合物 T10465BAY-1143572 S-Enantiomer；BAY-1143572 S-Enantiomer
Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is the (S)-enantiomer of BAY-1143572. Atuveciclib S-Enantiomer is a potent and selective CDK9 inhibitor, which inhibits CDK9 / CycT1 with an IC 50 of 16 nM.
价 格：￥电议型 号：T10465产 地：中国大陆
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T10462LBavisant dihydrochloride hydrate；化合物 T10462LJNJ31001074AAC；JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格：￥电议型 号：T10462L产 地：中国大陆
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T10462Bavisant dihydrochloride；化合物 T10462Bavisant dihydrochloride
Bavisant (JNJ-310010740) dihydrochloride is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition.
价 格：￥电议型 号：T10462产 地：中国大陆
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T10459Banoxantrone dihydrochloride；巴诺蒽醌盐酸盐Banoxantrone|||Banoxantrone dihydrochloride|||Banoxantrone|||AQ4
Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.
价 格：￥电议型 号：T10459产 地：中国大陆
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T10458Banoxantrone (D12)；化合物 T10458Banoxantrone (D12)|||Banoxantrone D12|||Banoxantrone (D-12)|||Banoxantr
Banoxantrone D12 (AQ4N D12) is the deuterium-labeled Banoxantrone. Banoxantrone is a bioreductive agent that can be reduced to a stable, DNA-affinity compound AQ4, which is a topoisomerase II inhibitor.
价 格：￥电议型 号：T10458产 地：中国大陆
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T1045Trimipramine maleate；三甲丙咪嗪马来酸盐Surmontil maleate；Surmontil maleate|||马来酸三甲丙咪嗪|||三甲丙咪嗪马来酸盐
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Maleate is the maleate salt form of trimipramine, a tricyclic secondary amine of the dibenzazepine class, with an antidepressant property.
价 格：￥电议型 号：T1045产 地：中国大陆
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T10404ATP synthase inhibitor 1；化合物ATP synthase inhibitor 1ATP synthase inhibitor 1
ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) opening and does not affect ATP levels.
价 格：￥电议型 号：T10404产 地：中国大陆
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T10359AR antagonist 1；化合物AR antagonist 1AR antagonist 1
AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.
价 格：￥电议型 号：T10359产 地：中国大陆
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T10351Aprocitentan D4；化合物 T10351ACT-132577 D4；ACT-132577 D4
Aprocitentan D4 (ACT-132577 D4) is a deuterium-labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is a dual ETA/ETB antagonist (IC50s: 3.4 nM and 987 nM; pA2s: 6.7 and 5.5).
价 格：￥电议型 号：T10351产 地：中国大陆
