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T9611PF-04802367PF367,PF 367,protein,disease,Alzheimer,PF-04802367,PF-367,Glycogen synthase kinase-3,kina
PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and potency. It is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3α and GSK-3β) with IC50 values of 10.0 and 9.0 nM in mobility shift assays, respectively.
价 格：￥电议型 号：T9611产 地：中国大陆
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TN2030P-Hydroxyphenethyl trans-ferulateGlucosidase,inhibit,P Hydroxyphenethyl trans ferulate,Inhibitor,PHy
P-Hydroxyphenethyl trans-ferulate exhibits affinity toward 5-HT(7) receptors in a competitive binding assay. P-Hydroxyphenethyl trans-ferulate can double quinone reductase specific activity in Hepa 1c1c7 cells at a level of 2.1 microg/mL (6.6 microM).
价 格：￥电议型 号：TN2030产 地：中国大陆
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T25310Dersimelagon
Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation.
价 格：￥电议型 号：T25310产 地：中国大陆
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T7149S29434cell-permeable,inhibit,selective,S 29434,HepG2,mice,NMDPEF,S-29434,ROS,Autophagy,S29434,Inhibi
S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
价 格：￥电议型 号：T7149产 地：中国大陆
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TN13458-Hydroxybergapten8-Hydroxybergapten,inhibit,8Hydroxybergapten,8 Hydroxybergapten,Inhibitor
8-Hydroxybergapten may have anti-wrinkle activity.
价 格：￥电议型 号：TN1345产 地：中国大陆
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TQ0021NingetinibVascular endothelial growth factor receptor,inhibit,c-Met/HGFR,TAM Receptor,Mer,Tyro3,VEGF
Ningetinib (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
价 格：￥电议型 号：TQ0021产 地：中国大陆
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TP1427LReACp53 acetateReACp53 acetate
ReACp53 acetate could inhibit p53 amyloid formation and rescue p53 function in cancer cell lines.
价 格：￥电议型 号：TP1427L产 地：中国大陆
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T9356(E/Z)-GO289Inhibitor,cancer,(E/Z)GO289,circadian,(E/Z)-GO-289,cell,clock,rhythms,growth,(E/Z) GO289,
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E/Z)-GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity.
价 格：￥电议型 号：T9356产 地：中国大陆
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T7821DG172 dihydrochlorideDG-172,DG172,DG172 dihydrochloride,PPAR,inhibit,DG 172,Inhibitor,Peroxisome pro
DG172 (dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).
价 格：￥电议型 号：T7821产 地：中国大陆
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T6376Allopurinol Sodiumanti-nociception,HIF-2α,inhibit,anti-leishmanial,gout,hyperuricemia,HIF-1α,HUVEC c
Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
价 格：￥电议型 号：T6376产 地：中国大陆
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TQ0232UNC0646H3K9me2,KMT1D,chromatin,EHMT1,Histone Methyltransferase,UNC-0646,SAR,inhibit,G9a,GLP,PKMT,UNC
UNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646 potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells); exhibits low cellular toxicity (EC50: 4.7 μM in MCF7 cells).
价 格：￥电议型 号：TQ0232产 地：中国大陆
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T7041DonepezilE 2020,AChE,Donepezil,Cholinesterase (ChE),Inhibitor,E-2020,inhibit,hAChE,bAChE
Donepezil is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate dementia of the Alzheimer´s type.
价 格：￥电议型 号：T7041产 地：中国大陆
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TQ0096Scabertopininhibit,Scabertopin,Inhibitor
Scabertopin has a significant antitumor effect in vitro in a concentration-dependent manner. It isolated from the whole plant of Elephantopus scaber.
价 格：￥电议型 号：TQ0096产 地：中国大陆
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T9215ELOVL6-IN-2ELOVL6IN2,ELOVL6 IN 2,plasma,inhibit,selective,ELOVL-6-IN-2,liver,dose-proportionally,Inh
ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
价 格：￥电议型 号：T9215产 地：中国大陆
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TQ0113Iclapriminhibit,AR 100,Bacterial,Iclaprim,Inhibitor,Antibiotic,AR100
Iclaprim is a novel specific bacterial Dihydrofolate inhibitor. It can inhibit the growth of S. aureus (MIC90: 0.06 μg/mL).
价 格：￥电议型 号：TQ0113产 地：中国大陆
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T7733CefotaximeHR-756,Bacterial,Cefotaxim,Antibiotic,Inhibitor,Cefotaxime,HR 756,inhibit,HR756
Cefotaxime is an inhibitor of penicillin binding protein.
价 格：￥电议型 号：T7733产 地：中国大陆
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T7361VerucerfontGSK 561679,Verucerfont,Corticotropin-releasing Factor Receptor,Inhibitor,GSK-561679,CRFR,
Verucerfont is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .
价 格：￥电议型 号：T7361产 地：中国大陆
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T7329C-178MITA,inhibit,Inhibitor,STING,MPYS,C178,ERIS,C-178,C 178,Stimulator of Interferon Genes,TMEM173
C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.
价 格：￥电议型 号：T7329产 地：中国大陆
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TP1344LuciferaseInhibitor,Luciferase,inhibit,Reactive Oxygen Species
Luciferase is a flavin-dependent monooxygenase found in bioluminescent bacteria. Luciferase is an invaluable tool for identifying and characterizing functional variants, allowing investigations of gene expression, intracellular signaling, transcription factors, receptor activity, and protein folding.
价 格：￥电议型 号：TP1344产 地：中国大陆
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TN2011OmbuosideGynostemma pentaphyllum,antimicrobial,Parkinson?s disease,Bacterial,inhibit,Ombuoside,bacte
Ombuoside has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.
价 格：￥电议型 号：TN2011产 地：中国大陆
