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T23331SC 51089；化合物 SC 51089SC 51089 free base；SC 51089 free base
SC 51089 is a selective prostaglandin receptor PGE2 antagonist with selectivity for prostaglandin receptor subtypes and antinociceptive activity that improves motor deficits and rescues memory decline in the Huntington´s disease R6/1 mouse model .
价 格：￥电议型 号：T23331产 地：中国大陆
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T19559Seocalcitol；化合物 T19559EB 1089；EB 1089
Seocalcitol is an analog of vitamin D, binds vitamin D receptor protein from human osteosarcoma MG-63 cells(Kd : 0.27 nM).
价 格：￥电议型 号：T19559产 地：中国大陆
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T11089Doxercalciferol-D3；化合物 T11089Doxercalciferol-D3
Doxercalciferol-d3 is the deuterated form of Doxercalciferol and ACTS as vitamin D receptor activator (VDRA), which is a vitamin D2 analogue.
价 格：￥电议型 号：T11089产 地：中国大陆
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T10899CU-CPT17e；化合物CU-CPT17eCU-CPT17e
CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).
价 格：￥电议型 号：T10899产 地：中国大陆
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T10898Samuraciclib hydrochloride；化合物Samuraciclib hydrochlorideICEC0942 hydrochloride|||CT7001 hydrochlorid
Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold higher than CDK1, CDK2 (IC50 is 578 nM), CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 μM. Samuraciclib hydrochloride has anti-tumor effects.
价 格：￥电议型 号：T10898产 地：中国大陆
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T10897CT-721；化合物 T10897CT-721
CT-721 is a potent and time-dependent Bcr-Abl kinase inhibitor with an IC50 of 21.3 nM against wild-type Bcr-Abl kinase and has anti-chronic myeloid leukemia (CML) activity.
价 格：￥电议型 号：T10897产 地：中国大陆
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T10896LCSRM617 hydrochloride；盐酸CSRM617CSRM617 hydrochloride(787504-88-5 Free base)；CSRM617 hydrochloride(78
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the mouse model of prostate cancer [1]
价 格：￥电议型 号：T10896L产 地：中国大陆
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T10896CSRM617；化合物 T10896CSRM617
CSRM617 is a selective small molecule inhibitor of the transcription factor ONECUT2 (OC2, the main regulator of androgen receptor). The Kd in SPR analysis is 7.43 uM, which can directly bind to the OC2-HOX domain. CSRM617 induces apoptosis by cleaving the presence of Caspase-3 and PARP. CSRM617 is well tolerated in a mouse model of prostate cancer.
价 格：￥电议型 号：T10896产 地：中国大陆
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T10895CSN5i-3；化合物CSN5i-3CSN5i-3
CSN5i-3 is a novel potent oral and selective CSN5/Jab1 inhibitor that inhibits CSN-catalyzed Cul1 deneddylation with an IC50 value of 5.8 nM.CSN5i-3 exhibits anticancer activity, inhibits cell proliferation and induces apoptosis in human breast cancer cells.
价 格：￥电议型 号：T10895产 地：中国大陆
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T10894CSF1R-IN-1；化合物CSF1R-IN-1CSF1R-IN-1
CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.
价 格：￥电议型 号：T10894产 地：中国大陆
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T10893CS-722 Free base；化合物CS-722 Free baseCS-722 Free base
CS-722 Free base is a synthetic central muscle relaxant with muscle relaxant activity and inhibitory effect on spinal reflex. CS-722 Free base may inhibit spontaneous inhibitory post-synaptic current and excitatory post-synaptic current in hippocampal culture by inhibiting sodium current and calcium current.
价 格：￥电议型 号：T10893产 地：中国大陆
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T10892CS-003 Free base；化合物 T10892CS-003 Free base
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 nM and 0.54 nM, respectively And 0.74 nM. CS-003 free base (CS-003) has therapeutic effects on neurokinin-related respiratory diseases.
价 格：￥电议型 号：T10892产 地：中国大陆
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T10891CRTH2-IN-1；化合物 T10891Ramatroban analog；Ramatroban analog
CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.
价 格：￥电议型 号：T10891产 地：中国大陆
