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T31115CV-1674;化合物 T31115NSC 310669|||CV 1674;NSC 310669|||CV 1674
CV-1674 induced selective coronary vasodilation and had little effect on cardiac hemodynamics.
价 格:¥电议型 号:T31115产 地:中国大陆
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T2S1115Albaspidin AA;白绵马素AAAlbaspidin AA
Albaspidin AA displays strong antibacterial activity against the vegetative form of P. larvae (MIC ranging from 0.168-220 uM). It may have in vitro nematocidal activity against L4 stage larvae.
价 格:¥电议型 号:T2S1115产 地:中国大陆
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T27248Egis-11150;化合物 Egis-11150Egis-11150
Egis-11150 is an anti-neuropathy compound with pro-cognitive effects.
价 格:¥电议型 号:T27248产 地:中国大陆
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T26955Cavosonstat;卡伏索司他N91115|||N 91115|||N-91115;N91115|||N 91115|||N-91115
Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor that promotes cystic fibrosis transmembrane conductance regulator (CFTR) maturation and plasma membrane stabilization.Cavosonstat is a CFTR stabilizer and can be used to study cystic fibrosis.
价 格:¥电议型 号:T26955产 地:中国大陆
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T263822-Mc-1,4-NHQ;化合物 T26382NSC 111552|||NSC-111552|||NSC111552;NSC 111552|||NSC-111552|||NSC111552
2-Mc-1,4-NHQ, an inhibitor of the Cdc42-PBD interaction, blocks the association of Cdc42 with the PBD.
价 格:¥电议型 号:T26382产 地:中国大陆
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T24688PV-1115;化合物 T24688PV1115;PV1115
PV-1115 is an effective and highly selective inhibitor of the Chk2.
价 格:¥电议型 号:T24688产 地:中国大陆
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T23201PSB 1115;化合物PSB 1115PSB 1115
PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.
价 格:¥电议型 号:T23201产 地:中国大陆
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T21115Timonacic, (S)-;化合物 T21115Timonacic, (S)-
Timonacic, (S)- is a cyclic sulfur amino acid derivative with potential antioxidant and antineoplastic activities. Timonacic may induce malignant cells to revert back to an untransformed state by acting on cellular membranes of malignant cells through an unknown mechanism. Timonacic may also produce antioxidant effects secondary to its release of cysteine and restoration of glutathione concentrations.
价 格:¥电议型 号:T21115产 地:中国大陆
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T11159EGFR-IN-2;化合物 T11159EGFR-IN-2
EGFR-IN-2 is a non-covalent, mutation-selective and irreversible second-generation EGFR inhibitor.
价 格:¥电议型 号:T11159产 地:中国大陆
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T11158EGFR-IN-11;化合物EGFR-IN-11EGFR-IN-11
EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1.
价 格:¥电议型 号:T11158产 地:中国大陆
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T11157LEGFR-IN-1 hydrochloride;EGFR-IN-1盐酸盐EGFR-IN-1 hydrochloride
EGFR-IN-1 hydrochloride is an irreversible and specific inhibitor of L858R/T790M mutant EGFR with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 hydrochloride exhibits potent antitumor and antiproliferative activity in H1975 cells and the mutant HCC827 cells with IC50s of 4 and 28 nM, respectively.
价 格:¥电议型 号:T11157L产 地:中国大陆
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T11157EGFR-IN-1;化合物 T11157EGFR-IN-1
EGFR-IN-1, an orally active and irreversible selective inhibitor targeting L858R/T790M mutant EGFR, exhibits strong antiproliferative and antitumor activity, particularly against H1975 cells and first line mutant HCC827 cells. This compound potently inhibits Gefitinib-resistant EGFR L858R/T790M mutations with a 100-fold selectivity over the wild-type EGFR.
价 格:¥电议型 号:T11157产 地:中国大陆
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T11156LNazartinib mesylate;化合物 T11156LEGF816 (mesylate);EGF816 (mesylate)
Nazartinib mesylate is a novel, covalent mutant-selective inhibitor of EGFR (Ki and Kinact: 31 nM and 0.222/min on EGFR(L858R/790M) mutant).
价 格:¥电议型 号:T11156L产 地:中国大陆
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T11156Nazartinib S-enantiomer;化合物 T11156EGF816 (S-enantiomer);EGF816 (S-enantiomer)
Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.
价 格:¥电议型 号:T11156产 地:中国大陆
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T11155Eg5 Inhibitor V, trans-24;化合物Eg5 Inhibitor V, trans-24Eg5 Inhibitor V, trans-24
Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.
价 格:¥电议型 号:T11155产 地:中国大陆
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T11154LEG01377 2HCl;EG01377二盐酸盐EG01377 2HCl(2227996-00-9 Free base);EG01377 2HCl(2227996-00-9 Free base)
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.
价 格:¥电议型 号:T11154L产 地:中国大陆
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T11154EG01377;化合物 T11154EG01377
EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 μM for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP2.
价 格:¥电议型 号:T11154产 地:中国大陆
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T11153EG00229;化合物 T11153EG00229
EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain, achieving this inhibition with an IC50 value of 3 μM. It does not affect the binding of VEGF-A to other receptors, such as VEGFR-1 and VEGFR-2.
价 格:¥电议型 号:T11153产 地:中国大陆
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T11152Edaravone-d5;化合物 T11152MCI-186 D5;MCI-186 D5
Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the original compound´s attributes while offering isotopic labeling benefits.
价 格:¥电议型 号:T11152产 地:中国大陆
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T11151Ecteinascidin-Analog-1;化合物 T11151Ecteinascidin-Analog-1
Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities. Ecteinascidin-Analog-1 is a useful intermediate for chemical sythesis of Ecteinascidin analogues.
价 格:¥电议型 号:T11151产 地:中国大陆