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  • T21644LAF 12198 Acetate；化合物AF 12198 AcetateAF 12198 Acetate (185413-30-3 Free base)；AF 12198 Acetate (18541

    AF 12198 Acetate is a novel low molecular weight antagonist of IL-1

    价 格：￥电议型 号：T21644L产 地：中国大陆

  • T18549(+)-Biotin-PEG2-hydrazide；化合物 T18549(+)-Biotin-PEG2-hydrazide

    (+)-Biotin-PEG2-hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T18549产 地：中国大陆

  • T18548(+)-Biotin-PEG12-OH；化合物 T18548(+)-Biotin-PEG12-OH

    (+)-Biotin-PEG12-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T18548产 地：中国大陆

  • T18547(+)-Biotin-PEG10-OH；化合物 T18547(+)-Biotin-PEG10-alcohol；(+)-Biotin-PEG10-alcohol

    (+)-Biotin-PEG10-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T18547产 地：中国大陆

  • T18546(+)-Biotin-ONP(+)-生物素对硝基苯酯(+)-生物素对硝基苯酯|||(+)-Biotin 4-nitrophenyl ester

    (+)-Biotin-ONP ((+)-Biotin 4-nitrophenyl ester) is an alkyl chain-based PROTAC linker. (+)-Biotin-ONP can be used in the synthesis of PROTACs.

    价 格：￥电议型 号：T18546产 地：中国大陆

  • T18545Pip-alkyne-Ph-COOCH3；化合物 T18545Pip-alkyne-Ph-COOCH3

    Pip-alkyne-Ph-COOCH3 is an alkyl-chain based PROTAC linker utilized for the synthesis of PROTAC ARD-266[1].

    价 格：￥电议型 号：T18545产 地：中国大陆

  • T18544Phthalimide-PEG4-PDM-OTBS；化合物 T18544Phthalimide-PEG4-PDM-OTBS

    Phthalimide-PEG4-PDM-OTBS is a PROTAC linker comprised of polyethylene glycols (PEGs). This compound is utilized in the synthesis of a range of PROTACs, which consists of two distinct ligands connected by a linker. One ligand binds to an E3 ubiquitin ligase, while the other ligand binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1].

    价 格：￥电议型 号：T18544产 地：中国大陆

  • T18543Phthalimide-PEG4-MPDM-OH；化合物 T18543Phthalimide-PEG4-MPDM-OH

    Phthalimide-PEG4-MPDM-OH, a PROTAC linker with a PEGs composition, has applications in the synthesis of various PROTACs. These PROTACs consist of a linker connecting two distinct ligands: one binds to an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively induce the degradation of target proteins [1].

    价 格：￥电议型 号：T18543产 地：中国大陆

  • T18542Phthalimide-PEG3-C2-OTs；化合物 T18542Phthalimide-PEG3-C2-OTs

    Phthalimide-PEG3-C2-OTs (Compound 5) is a PROTAC linker composed of PEGs. It is utilized in the synthesis of various PROTACs, which involve the connection of two distinct ligands through a linker. One ligand is specific for an E3 ubiquitin ligase, while the other ligand is designed for targeting the specific protein of interest. Through leveraging the intracellular ubiquitin-proteasome system, PROTACs are capable of selectively degrading target proteins [1].

    价 格：￥电议型 号：T18542产 地：中国大陆

  • T18541Phthalamide-PEG3-azide；化合物 T18541Phthalamide-PEG3-azide

    Phthalamide-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T18541产 地：中国大陆

  • T18540Phe-Lys(Trt)-PAB；化合物Phe-Lys(Trt)-PABPhe-Lys(Trt)-PAB

    Phe-Lys(Trt)-PAB is a cathepsin-cleavable linker utilized in the development of antibody-drug conjugates (ADCs)[1], serving as a crucial component for facilitating the release of therapeutic agents within targeted cells.

    价 格：￥电议型 号：T18540产 地：中国大陆

  • T1854MS436；化合物MS436MS436

    MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.

    价 格：￥电议型 号：T1854产 地：中国大陆

  • T11854Lipofermata；化合物LipofermataLipofermata

    Lipofermata is a fatty acid transport protein (FATP) inhibitor that prevents lipid transport to melanoma cells and reduces melanoma growth and invasion.

    价 格：￥电议型 号：T11854产 地：中国大陆

  • T0455Clozapine；氯氮平HF 1854|||LX 100-129；氯氮平|||HF 1854|||LX 100-129

    Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity.

    价 格：￥电议型 号：T0455产 地：中国大陆

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