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T61929PD-1/PD-L1-IN-14;化合物 PD-1/PD-L1-IN-14PD-1/PD-L1-IN-14
PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM). By inhibiting the interaction of PD-1/PD-L1, PD-1/PD-L1-IN-14 promotes dimerization, endocytosis and degradation of PD-L1.
价 格:¥电议型 号:T61929产 地:中国大陆
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T37579GW 1929 hydrochlorideGW 1929 hydrochlorideGW 1929 hydrochloride
Highly selective orally active peroxisome proliferator-activated receptor (PPAR)γ agonist (pEC50 values are 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors respectively). Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo.
价 格:¥电议型 号:T37579产 地:中国大陆
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T31929Giripladib;吉立拉地PLA 695|||PLA-695|||PLA695;PLA 695|||PLA-695|||PLA695
Giripladib (PLA695)(PLX-695) is a cPLA2-specific inhibitor that inhibits the radiation-induced increase of phosphorylated ERK and phosphorylated Akt in endothelial cells.
价 格:¥电议型 号:T31929产 地:中国大陆
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T19299DTE化合物 T19299Cleland’s reagent|||Dithioerythritol
Dithioerythritol (DTE), a sulfur-containing sugar derivative of the 4-carbon monosaccharide erythrose, is an epimer of dithiothreitol (DTT).
价 格:¥电议型 号:T19299产 地:中国大陆
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T19297Doxazosin D8;化合物 T19297UK 33274 D8;UK 33274 D8
Doxazosin D8 (UK 33274 D8) is a deuterium labeled Doxazosin (UK 33274).Doxazosin, a quinazoline derivative, selectively antagonizes postsynaptic AP1 adrenergic receptor.
价 格:¥电议型 号:T19297产 地:中国大陆
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T19296DOTA derivative;化合物 T19296DOTA derivative
DOTA derivatives are phenoxy derivatives of cyclic Tosamide;Direct nitrification;It is more convenient to add nitro group after removing the protection of lithium aluminium hydride.
价 格:¥电议型 号:T19296产 地:中国大陆
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T19295Docosapentaenoic acid 22n-3;二十二碳五烯酸Docosapentaenoic acid 22n-3
Docosapentaenoic acid 22n-3 is present in the cell membranes of all animals and is a component of phospholipids.
价 格:¥电议型 号:T19295产 地:中国大陆
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T19294Docosahexaenoic Acid methyl ester;二十二六烯酸甲酯Methyl docosahexaenoate|||all cis-DHA methyl ester;二十二六烯酸甲
Docosahexaenoic Acid methyl ester (all cis-DHA methyl ester) is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed.
价 格:¥电议型 号:T19294产 地:中国大陆
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T19293DO3A tert-Butyl ester;化合物 T19293DO3A-t-Bu-ester|||DO3A tert-butyl;DO3A-t-Bu-ester|||DO3A tert-butyl
DOTA tert-butyl ester is a phenyl derivative of cycloteramide; it can be directly nitrated; it is more convenient to add nitro after deprotection of lithium aluminum hydride.
价 格:¥电议型 号:T19293产 地:中国大陆
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T19292DL-threo-2-methylisocitrate;化合物 T19292DL-threo-2-methylisocitrate
dl-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1). IC50 value: target: using michael-menten nonlinear least squares fitting to determine the purified recombinant ICL1´s Km for threo-D(s)L(s)-isocitrate (ICA) is 188°M and kcat is 5.24 s- 1. The Km of DL-threo-2-methylisocitrate (MICA) is about 4 times that of 718, and the kcat is 1.25 s-1.
价 格:¥电议型 号:T19292产 地:中国大陆
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T19291DL-threo-2-methylisocitrate sodium;化合物 T19291DL-threo-2-methylisocitrate sodium
DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1). Using Michaelis-Menten nonlinear least squares fitting, kcat value was 5.24 s-1, the Km of the purified recombinant ICL1 of threonine-D(s)L(s)-isocitrate (ICA) was 188 μM. The Km of DL-threo-2-methylisocitrate (MICA) is approximately four times higher at 718 μM, and the kcat is 1.25 s-1.
价 格:¥电议型 号:T19291产 地:中国大陆
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T19290DL-Lysine;化合物 T19290(±)-2,6-Diaminocaproic acid;(±)-2,6-Diaminocaproic acid
DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
价 格:¥电议型 号:T19290产 地:中国大陆
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T1929Filgotinib;化合物FilgotinibGLPG0634;GLPG0634
Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.
价 格:¥电议型 号:T1929产 地:中国大陆
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T11929M2N12;化合物M2N12M2N12
M2N12 is a potent and highly selective inhibitor of cell division cycle 25C protein phosphatase (Cdc25C, IC50 = 0.09 μM). M2N12 has anti-tumor activity. M2N12 also has promising activity against Cdc25A(IC50 = 0.53? μM) and Cdc25B(IC50 = 1.39 μM).
价 格:¥电议型 号:T11929产 地:中国大陆
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T11830LDN-192960 hydrochloride化合物 T11830LDN192960 hydrochloride|||LDN 192960 hydrochloride
LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.
价 格:¥电议型 号:T11830产 地:中国大陆