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Ʒ86101
ι۴3259929
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T86096-Bromo-3-methyl-1,4-dihydroquinazolin-2-one6-Bromo-3-methyl-1,4-dihydroquinazolin-2-one6-Bromo-3-m
CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).
ţT8609 أй½
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T8579Nav1.8-IN-1T85795-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-c
Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8
ţT8579 أй½
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T836622,3-dinor-8-iso Prostaglandin F1 2,3-dinor-8-iso Prostaglandin F12,3-dinor-8-iso PGF1|||2,3-d
2,3-Dinor-8-iso Prostaglandin F1 (2,3-dinor-8-iso PGF1), an isoprostane and active metabolite of arachidonic acid deriving its formation from non-enzymatic free radical peroxidation, acts as an active metabolite of the platelet aggregation inhibitor 8-iso PGF2. This compound exhibits vasoconstrictive properties in isolated porcine retinal and brain microvessels with EC50 values of 12.8 and 18.5 nM, respectively, yet it does not cause contraction in isolated rat aortic rings at a concentration
ţT83662 أй½
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T8356FPL 62064N-(4-)-1--1H--3-FPL 62064
FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 M and 3.1 M for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase, respectively).
ţT8356 أй½
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T80502-Methyltetrahydrofuran-3-one2--3-ͪ2-Methyltetrahydrofuran-3-one
2-Methyltetrahydrofuran-3-one, also known as fema 3373 or tetrahydro-2-methyl-3-furanone, belongs to the class of organic compounds known as furanones.
ţT8050 أй½
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T79013SLMP53-2 SLMP53-2SLMP53-2
SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with Hsp70, thereby reinstating p53´s transcriptional activity. This compound induces cell cycle arrest, apoptosis, and endoplasmic reticulum (ER) stress, displaying antitumor activity [1] [2].
ţT79013 أй½
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T77960Thalidomide-5-O-C13-NH2 hydrochloride Thalidomide-5-O-C13-NH2 hydrochlorideThalidomide-5-O-C13-N
Thalidomide-5-O-C13-NH2 hydrochloride, a cereblon ligand derived from Thalidomide, facilitates the recruitment of CRBN protein. It is designed to conjugate with a ligand for protein recruitment through a linker, enabling the formation of PROTACs [1].
ţT77960 أй½
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T77936-(4-Methoxyphenyl)-3-pyridazinamine6-(4-)-3-6-(4-Methoxyphenyl)-3-pyridazinamine
6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist
ţT7793 أй½
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T777002-Butyl-1,2-benzisothiazolin-3-one2--1,2--3-ͪ2-butylbenzo[d]isothiazol-3(2H)-one2-butylben
2-Butyl-1,2-benzisothiazolin-3-one is an orally available antimicrobial agent with antimicrobial activity commonly used in the pharmaceutical profession and food processing.
ţT77700 أй½
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T75441(8,9-Dihydroxy)-3-farnesylindole (8,9-Dihydroxy)-3-farnesylindole(8,9-Dihydroxy)-3-f
(8´,9´-Dihydroxy)-3-farnesylindole exhibits significant inhibitory effectiveness (EC 50 9.8 M) against B. subtilis.
ţT75441 أй½
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T75417alpha-1,3-Galactosyltransferase (a1,3GalT) alpha-1,3-Galactosyltransferase (a1,3GalT)alpha-1,3-G
Alpha-1,3-Galactosyltransferase (a1,3GalT) (GGTA1) catalyzes the synthesis of the -gal epitope by transferring a galactose (Gal) molecule in an 1-3 linkage from a uridyl-diphosphate (UDP) donor to the N-acetyllactosamine (Gal1,4GlcNAc-R) on glycoproteins. This enzyme is essential for the production of the -galactose (-Gal) epitope, a biomolecule prevalent in most mammalian species [1].
ţT75417 أй½
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T74554Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH Tazemetostat de(methylene morpholine)-O-C3-O
Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH (Compound 21b), an EZH2 degrader, is employed in lymphoma research [1].
ţT74554 أй½
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T71998673-A 673-A673-A
673-A is an aldehyde dehydrogenase (ALDH1A) inhibitor that depletes CD133+ cancer stem cells (CSC) in ovarian cancer cell lines. 673-A triggers necroptosis in ovarian CSCs and induces expression of mitochondrial uncoupling proteins (UCP). 673-A also overcomes chemotherapy resistance in vivo.
ţT71998 أй½
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T7138FB23-2FB23-2FB23-2
FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 M).
ţT7138 أй½
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T70470Lisomer-CM 352CM 352칹isomer-1542205-83-3isomer-1542205-83-3
isomer-CM 352 is a metalase inhibitor that can be used to slow brain damage.
ţT70470L أй½
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T69486BMD4503-2 BMD4503-2BMD4503-2
BMD4503-2 is an LRP5/6-sclerostin interaction inhibitor. BMD4503-2 recovers the downregulated activity of the Wnt/-catenin signaling pathway by competitively binding to the LRP5/6-sclerostin complex.
ţT69486 أй½
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T69316DA 3003-2 DA-3003-2NSC663285NSC663285
DA 3003-2, a selectively potent Cdc25 inhibitor, exhibits antiproliferative activity and holds potential for prostate cancer research. It induces cell cycle arrest at the G2/M phase and increases the expression of P-tyr 15 Cdc2.
ţT69316 أй½
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T67647(2R,3R)-2-Amino-3-hydroxybutanoic acid (2R,3R)-2-Amino-3-hydroxybutanoic acid(2R,3R)-2-Amino-3-h
(2R,3R)-2-Amino-3-hydroxybutanoic acid is a natural product for research related to life sciences. The catalog number is T67647 and the CAS number is 24830-94-2.
ţT67647 أй½
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T67603(S)-2-(Cbz-amino)-3-phenyl-1-propanol (S)-2-(Cbz-amino)-3-phenyl-1-propanol(S)-2-(Cbz-amino)-3-p
(S)-2-(Cbz-amino)-3-phenyl-1-propanol is a useful organic compound for research related to life sciences. The catalog number is T67603 and the CAS number is 6372-14-1.
ţT67603 أй½
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T67456Argatroban Related Compound A (2R,4R)-4-Methyl-1-((S)-2-(3-methylquinoline-8-sulfonamido)-5-(3-n
(2R,4R)-4-Methyl-1-((S)-2-(3-methylquinoline-8-sulfonamido)-5-(3-nitroguanidino)pentanoyl)piperidine-2-carboxylic acid is a useful organic compound for research related to life sciences and the catalog number is T67456.
ţT67456 أй½