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  • T79677SARS-CoV-2-IN-58；化合物 SARS-CoV-2-IN-58SARS-CoV-2-IN-58

    SARS-CoV-2-IN-58 (Compound 21H) serves as an antiviral agent targeting SARS-CoV-2, demonstrating efficacy with an EC50 of 18 μM. It specifically inhibits the SARS-CoV-2 main protease (Mpro) with an IC50 value of 0.35 μM [1].

    价 格：￥电议型 号：T79677产 地：中国大陆

  • T79661SARS-CoV-2 3CLpro-IN-18；化合物 SARS-CoV-2 3CLpro-IN-18SARS-CoV-2 3CLpro-IN-18

    SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.478 μM. It demonstrates inhibition of SARS-CoV-2 in Vero E6 cells, with an EC50 of 2.499 μM, and exhibits low cytotoxicity (CC50 > 200 μM) [1].

    价 格：￥电议型 号：T79661产 地：中国大陆

  • T79609STAT3-IN-18；化合物 STAT3-IN-18STAT3-IN-18

    STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and exhibits anti-proliferative properties. It promotes apoptosis by activating caspase-3 and elevating levels of cleaved polyADP-ribose polymerase, in addition to enhancing maturation and antigen presentation in dendritic cells. Moreover, STAT3-IN-18 has demonstrated in vivo safety.

    价 格：￥电议型 号：T79609产 地：中国大陆

  • T79604SHR5428；化合物 SHR5428SHR5428

    SHR5428 is an orally active, selective, noncovalent inhibitor of CDK7, displaying potent enzymatic inhibition (IC50 = 2.3 nM) and effectively suppressing cellular activity in triple-negative breast cancer MDA-MB-468 cells (IC50 = 6.6 nM) [1].

    价 格：￥电议型 号：T79604产 地：中国大陆

  • T79443Syk-IN-8；化合物 Syk-IN-8Syk-IN-8

    Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells. It specifically inhibits PLCγ2 phosphorylation and is applicable for blood cancer research [1].

    价 格：￥电议型 号：T79443产 地：中国大陆

  • T79279SARS-CoV-2 Mpro-IN-8；化合物 SARS-CoV-2 Mpro-IN-8SARS-CoV-2 Mpro-IN-8

    SARS-CoV-2 Mpro-IN-8 (compound 6b) is an antiviral agent effective against SARS-CoV-2 [1].

    价 格：￥电议型 号：T79279产 地：中国大陆

  • T79124JGK-068S；化合物 JGK-068SJGK-068S

    Compound I (JGK-068S) is a potent inhibitor of the epidermal growth factor receptor (EGFR) [1].

    价 格：￥电议型 号：T79124产 地：中国大陆

  • T78961SARS-CoV-2-IN-38；化合物 SARS-CoV-2-IN-38SARS-CoV-2-IN-38

    SARS-CoV-2-IN-38, also known as compound 24, is an inhibitor of SARS-CoV-2 that demonstrates favorable oral bioavailability in mice, with an absorption fraction of 39.75% [1].

    价 格：￥电议型 号：T78961产 地：中国大陆

  • T78891SDH-IN-8；化合物 SDH-IN-8SDH-IN-8

    SDH-IN-8 (compound G40) is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 value of 27 nM against porcine SDH and exhibits fungicidal properties [1].

    价 格：￥电议型 号：T78891产 地：中国大陆

  • T78856SIRT5 inhibitor 8；化合物 SIRT5 inhibitor 8SIRT5 inhibitor 8

    SIRT5 inhibitor 8 (compound 10) serves as a competitive inhibitor of sirtuin SIRT5, exhibiting an IC50 of 5.38 μM, and possesses anticancer potential [1].

    价 格：￥电议型 号：T78856产 地：中国大陆

  • T78720SARS-CoV-2-IN-48；化合物 SARS-CoV-2-IN-48SARS-CoV-2-IN-48

    SARS-CoV-2-IN-48 (compound 19) is an inhibitor of SARS-CoV-2, exhibiting an IC50 of 2.7 μM against the Omicron BA.1 variant and demonstrating antiviral activities [1].

    价 格：￥电议型 号：T78720产 地：中国大陆

  • T7837SR8278；化合物SR8278SR8278

    SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM), blocking activation of the receptor by the synthetic agonist GSK 4112

    价 格：￥电议型 号：T7837产 地：中国大陆

  • T78211STX-478；化合物 STX-478STX-478

    STX-478 (compound 80), an orally administered, CNS-penetrant allosteric mutant-selective PI3Kα inhibitor, demonstrates significant and sustained tumor regression, making it a valuable agent in cancer research [1].

    价 格：￥电议型 号：T78211产 地：中国大陆

  • T75096STING agonist-28；化合物 STING agonist-28STING agonist-28

    STING agonist-23 (CF510) is a non-nucleotide, small-molecule activator of the STING pathway. It initiates the phosphorylation of STING, TBK1, and IRF3, enhancing the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. Notably, it demonstrates activity against SARS-CoV series strains [1].

    价 格：￥电议型 号：T75096产 地：中国大陆

  • T74946SARS-CoV-2-IN-28；化合物 SARS-CoV-2-IN-28SARS-CoV-2-IN-28

    SARS-CoV-2-IN-28, a two-armed diphosphate ester featuring a C7 alkyl chain and molecular tweezers of extended length, demonstrates antiviral properties by exhibiting IC 50 values of 0.4 μM against SARS-CoV-2 activity and 1.0 μM against spike pseudoparticle transduction. Additionally, it disrupts liposomal membranes, evidenced by an EC 50 value of 4.4 μM [1].

    价 格：￥电议型 号：T74946产 地：中国大陆

  • T74570SIAIS164018；化合物 SIAIS164018SIAIS164018

    SIAIS164018, a PROTAC-based ALK and EGFR degrader derived from Brigatinib, exhibits IC50 values of 2.5 nM for ALK and 6.6 nM for ALK G1202R. It significantly hampers cancer cell migration and invasion, induces G1 cell cycle arrest, and triggers apoptosis, demonstrating superior properties compared to Brigatinib [1].

    价 格：￥电议型 号：T74570产 地：中国大陆

  • T73554SPR38；化合物 SPR38SPR38

    SPR38, a potent inhibitor of the SARS-CoV-2 main protease, exhibits a Ki value of 0.260 μM. Additionally, it effectively inhibits human cathepsin L (hCatL) and human cathepsin B (hCatB), displaying Ki values of 1.92 μM and 11.1 μM, respectively.

    价 格：￥电议型 号：T73554产 地：中国大陆

  • T71711ST029248；化合物 ST029248ST029248

    ST029248 is a potent mast cell (MC) activator, promoting de novo synthesis of cytokines and inducing the release of eicosanoids from human and mouse MCs.

    价 格：￥电议型 号：T71711产 地：中国大陆

  • T71280S 8308；化合物 S 8308S 8308

    S 8308 is a weak, but specific and competitive, non-peptide antagonist of AII exerting its inhibitory action at the receptor level.

    价 格：￥电议型 号：T71280产 地：中国大陆

  • T71210S7958；化合物 S7958S7958

    S7958 is a is a TAS2R8 antagonist. It was found to be non-mutagenic in vitro.

    价 格：￥电议型 号：T71210产 地：中国大陆

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