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  • T2098A77-01A77-01

    A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.

    价 格：￥电议型 号：T2098产 地：美洲

  • T2113PHA-793887PHA-793887,PHA793887,PHA 793887

    PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.

    价 格：￥电议型 号：T2113产 地：美洲

  • T5101BW-A78UBW-A78U

    BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.

    价 格：￥电议型 号：T5101产 地：美洲

  • T5536SJA710-6SJA710-6

    SJA710-6 is a small molecule able to selectively differentiate MSCs toward hepatocyte-like cells.

    价 格：￥电议型 号：T5536产 地：美洲

  • T6206PHA-767491PHA-767491,PHA767491,PHA 767491

    PHA-767491 is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.

    价 格：￥电议型 号：T6206产 地：美洲

  • T838944A7C-301-Nurr1 Agonist；化合物 4A7C-301-Nurr1 Agonist4A7C-301-Nuclear Receptor-Related 1；4A7C-301-Nuclea

    The compound 4A7C-301-Nurr1 agonist is a specific agonist for the nuclear receptor-related 1 (Nurr1). By binding to the Nurr1 ligand-binding domain with an IC50 value of 48.22 nM, it enhances the transcriptional activity of both Nurr1-LBD and the full-length Nurr1, as demonstrated in reporter assays using SK-N-BE(2)C human neuroblastoma cells, with EC50 values of 6.53 and 50-70 ?M, respectively. Additionally, administration of 4A7C-301-Nurr1 agonist at a dosage of 5 mg/kg per day has been shown

    价 格：￥电议型 号：T83894产 地：中国大陆

  • T833284A7C-301；化合物 4A7C-3014A7C-301

    4A7C-301, a Nurr1 agonist, exhibits potent neuroprotective effects in vitro and markedly mitigates neuropathological abnormalities while enhancing motor and olfactory functions in male mouse models with AAV2-mediated α-synuclein overexpression. This compound is applicable in Parkinson’s disease research [1].

    价 格：￥电议型 号：T83328产 地：中国大陆

  • T832587(18)-Dehydroschisandro A；化合物 7(18)-Dehydroschisandro A7(18)-Dehydroschisandro A

    7(18)-Dehydroschisandro A (Compound 2), a lignan isolated from Schizandra chinensis Baill, exhibits inhibitory effects on stress-induced gastric ulcers [1].

    价 格：￥电议型 号：T83258产 地：中国大陆

  • T832577(8)-Dehydroschisandrol A；化合物 7(8)-Dehydroschisandrol A7(8)-Dehydroschisandrol A

    7(8)-Dehydroschisandrol A (Compound 4a), a lignan extracted from Schizandra chinensis Baill, exhibits a mild inhibitory activity against stress-induced gastric ulcers [1].

    价 格：￥电议型 号：T83257产 地：中国大陆

  • T832517-51A；化合物 7-51A7-51A

    7-51A is an effective inhibitor of the PB2 subunit of the influenza RNA-dependent RNA polymerase (RdRP), with a dissociation constant (K_D) of 1.64 nM as determined by isothermal titration calorimetry (ITC).

    价 格：￥电议型 号：T83251产 地：中国大陆

  • T81445PKRA83 hydrochloride hydrate；化合物 PKRA83 hydrochloride hydratePKRA7 hydrochloride hydrate；PKRA7 hydro

    PKRA83 hydrochloride hydrate, also known as PKRA7, is a potent prokineticin (PK2) antagonist that competes with PK2 for binding to its receptors, PKR1 and PKR2. It exhibits high inhibitory affinity with IC50 values of 5.0 nM for PKR1 and 8.2 nM for PKR2, displaying anticancer, anti-arthritis, and anti-angiogenic properties. Additionally, this compound is capable of crossing the blood-brain barrier [1] [2] [3].

    价 格：￥电议型 号：T81445产 地：中国大陆

  • T78435Mca-(ala7,lys(dnp)9)-bradykinin；化合物 Mca-(ala7,lys(dnp)9)-bradykininMca-(ala7,lys(dnp)9)-bradykinin

    Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1). It features a (7-methoxycoumarin-4-yl)acetyl (Mca) group for fluorescence and a 2,4-dinitrophenyl (Dnp) group for quenching, yielding a significant increase in fluorescence when the substrate is cleaved [1].

    价 格：￥电议型 号：T78435产 地：中国大陆

  • T78134AA74-1；化合物 AA74-1AA74-1

    AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].

    价 格：￥电议型 号：T78134产 地：中国大陆

  • T75723740 Y-P TFA；化合物 740 Y-P TFA740 Y-P TFA

    740 Y-P TFA, a potent, cell-permeable PI3K activator, exhibits selective binding affinity for GST fusion proteins encompassing the N- and C-terminal SH2 domains of p85, yet does not interact with GST in isolation [1].

    价 格：￥电议型 号：T75723产 地：中国大陆

  • T754877-Hydroxyneolamellarin A；化合物 7-Hydroxyneolamellarin A7-Hydroxyneolamellarin A

    7-Hydroxyneolamellarin A, a natural product from the sponge Dendrilla nigra, serves as a potent inhibitor of hypoxia-inducible factor-1α (HIF-1α). It effectively reduces the accumulation of HIF-1α protein and suppresses vascular epidermal growth factor (VEGF) transcriptional activity, making it valuable in cancer research [1].

    价 格：￥电议型 号：T75487产 地：中国大陆

  • T73217Crisnatol；化合物 CrisnatolBWA770U；BWA770U

    Crisnatol (BWA770U), an arylmethylaminopropanediol class DNA intercalator, serves as an orally active anticancer agent. It demonstrates in vitro cytotoxicity specifically against human breast cancer cells, while sparing normal human skin fibroblasts.

    价 格：￥电议型 号：T73217产 地：中国大陆

  • T7080CCT245737；化合物CCT245737SRA737；SRA737

    CCT245737 (SRA737) is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50: 2440 nM).

    价 格：￥电议型 号：T7080产 地：中国大陆

  • T6940PHA-767491 hydrochloride；化合物PHA767491 HClCAY10572|||PHA-767491|||PHA767491 HCl|||CAY-10572 hydrochlo

    PHA-767491 hydrochloride (CAY-10572 hydrochloride) is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.

    价 格：￥电议型 号：T6940产 地：中国大陆

  • T64689EX-A7140；化合物 EX-A7140EX-A7140

    (3S,7S,14R,23S,27S)-5,13,17,25-Tetraoxo-14-(2-oxo-1-(4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)-6,9,12,15-tetraoxa-3-azaoctadecanamido)-4,6,12,18,24,26-hexaazanonacosane-1,3,7,23,27,29-hexacarboxylic acid is a useful organic compound for research related to life sciences and the catalog number is T64689.

    价 格：￥电议型 号：T64689产 地：中国大陆

  • T6206PHA-767491；化合物PHA767491CAY10572|||PHA767491|||PHA 767491；CAY10572|||PHA767491|||PHA 767491

    PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.

    价 格：￥电议型 号：T6206产 地：中国大陆

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