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T83065Antifungal agent 85;化合物 Antifungal agent 85Antifungal agent 85
Compound 24f, an antifungal agent also known as ´Antifungal agent 85,´ demonstrates potent antibacterial properties, exhibiting minimum inhibitory concentration (MIC) values ranging from 2.5 to 10 μM against diverse Gram-positive bacteria [1].
价 格:¥电议型 号:T83065产 地:中国大陆
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T79759Antifungal agent 74;化合物 Antifungal agent 74Antifungal agent 74
Antifungal agent 74 (compound 3c), is a potent substance that exhibits excellent fungicidal activity against C. arachidicola and R. solani, functioning by disrupting steroid biosynthesis and ribosome biogenesis in eukaryotes [1].
价 格:¥电议型 号:T79759产 地:中国大陆
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T79589Antifungal agent 71;化合物 Antifungal agent 71Antifungal agent 71
Antifungal agent 71 (compound 6r), a trifluoromethyl pyrimidine derivative, displays potent in vitro activity against F. oxysporum, evidenced by an EC 50 value of 3.61 μg/mL [1].
价 格:¥电议型 号:T79589产 地:中国大陆
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T79552Antifungal agent 70;化合物 Antifungal agent 70Antifungal agent 70
Antifungal Agent 70 (Compound 13), a dihydroeugenol-imidazole, exhibits efficacy against multi-resistant Candida auris with a minimum inhibitory concentration (MIC) of 36.4 μM, demonstrating notable antifungal activity [1].
价 格:¥电议型 号:T79552产 地:中国大陆
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T79551Antifungal agent 69;化合物 Antifungal agent 69Antifungal agent 69
Antifungal agent 69 (compound 13), a eugenol-imidazole derivative, demonstrates targeted activity against Candida albicans with a minimum inhibitory concentration (MIC) of 4.6 μM, while exhibiting negligible cytotoxicity. This compound disrupts ergosterol biosynthesis, contributing to its antifungal efficacy [1].
价 格:¥电议型 号:T79551产 地:中国大陆
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T79550Antifungal agent 68;化合物 Antifungal agent 68Antifungal agent 68
Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterol biosynthesis, likely via interaction with lanosterol 14α-demethylase (CYP51). It is proposed that the imidazole ring of antifungal agent 68 interacts with the heme group of CYP51 [1].
价 格:¥电议型 号:T79550产 地:中国大陆
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T79549Antifungal agent 67;化合物 Antifungal agent 67Antifungal agent 67
Compound 9 (Antifungal agent 67), an imidazole class antifungal, exhibits efficacy against Candida and possesses a CC50 value of 33.6 μM in neonatal rat cardiomyoblasts [1].
价 格:¥电议型 号:T79549产 地:中国大陆
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T79545Antifungal agent 66;化合物 Antifungal agent 66Antifungal agent 66
Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects on the spores of B. cinerea, with an IC50 value of 47.7 μg/mL [1].
价 格:¥电议型 号:T79545产 地:中国大陆
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T79522Antifungal agent 65;化合物 Antifungal agent 65Antifungal agent 65
Compound 5d (Antifungal Agent 65) exhibits potent fungicidal activity against Fusarium oxysporum f.sp. cucumerinum and is utilized in antiviral and fungicidal research [1].
价 格:¥电议型 号:T79522产 地:中国大陆
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T79521Antifungal agent 64;化合物 Antifungal agent 64Antifungal agent 64
Compound 5c (Antifungal agent 64) exhibits potent fungicidal activity against Fusarium oxysporum f.sp. cucumerinum and is applicable for research in antiviral and fungicidal domains [1].
价 格:¥电议型 号:T79521产 地:中国大陆
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T79467Antifungal agent 60;化合物 Antifungal agent 60Antifungal agent 60
Antifungal agent 60 (compound 16), a broad-spectrum ergosterol biosynthesis inhibitor, demonstrates potent activity against seven human pathogenic fungal species, including two fluconazole-resistant C. albicans isolates and two multi-drug resistant Candida auris isolates.
价 格:¥电议型 号:T79467产 地:中国大陆
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T79413Antifungal agent 73;化合物 Antifungal agent 73Antifungal agent 73
Antifungal agent 73 (compound A32) effectively combats azole-resistant candidiasis by disrupting the fungal cell wall and membrane. It demonstrates potent in vivo activity against pathogenic fungi, including fluconazole-resistant strains [1].
价 格:¥电议型 号:T79413产 地:中国大陆
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T79384Antifungal agent 72;化合物 Antifungal agent 72Antifungal agent 72
Antifungal agent 72 (Compound B8) demonstrates potent activity by inhibiting the efflux pump function and downregulating resistance-associated genes via disruption of the Pdr1-KIX interaction (K i : 11.7 μM). It exhibits efficacy against Fluconazole-resistant strains, evidenced by a MIC of 63 ng/mL, and displays synergistic effects when combined with Fluconazole. This compound is particularly useful for researching C. glabrata infections [1].
价 格:¥电议型 号:T79384产 地:中国大陆
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T79298Antifungal agent 61;化合物 Antifungal agent 61Antifungal agent 61
Antifungal Agent 61 (Compound 38) is an antifungal agent that inhibits V. mali, with an EC50 value of 0.50 mg/L. This compound impedes V. mali´s growth by inducing cell deformation and contraction, diminishing intracellular mitochondrial count, thickening the cell wall, and enhancing cell membrane permeability [1].
价 格:¥电议型 号:T79298产 地:中国大陆
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T79087Antifungal agent 59;化合物 Antifungal agent 59Antifungal agent 59
Antifungal agent 59 exhibits potent activity, reflected by MIC values ranging from 0.01 to 1 μg/mL, and inhibits the formation of fungal biofilms, while maintaining safety [1].
价 格:¥电议型 号:T79087产 地:中国大陆
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T78908Antifungal agent 50;化合物 Antifungal agent 50Antifungal agent 50
Antifungal agent 50 exhibits minimum inhibitory concentrations (MICs) ranging from less than 0.063 to 1 μg/mL [1].
价 格:¥电议型 号:T78908产 地:中国大陆
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T78893Antifungal agent 78;化合物 Antifungal agent 78Antifungal agent 78
Antifungal agent 78 (compound 25am) exhibits potent activity, with an EC50 of 13.46 μM against Fusarium graminearum [1].
价 格:¥电议型 号:T78893产 地:中国大陆
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T78116Antifungal agent 49;化合物 Antifungal agent 49Antifungal agent 49
Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].
价 格:¥电议型 号:T78116产 地:中国大陆
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T78115Antifungal agent 48;化合物 Antifungal agent 48Antifungal agent 48
Antifungal agent 48 (Example 308), active against Cryptococcus neoformans, exhibits a minimum inhibitory concentration (MIC) value of 11 μM [1].
价 格:¥电议型 号:T78115产 地:中国大陆
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T75181Antifungal agent 58;化合物 Antifungal agent 58Antifungal agent 58
Antifungal agent 58 (compound A21) exhibits high potency against Fluconazole-resistant strains and outperforms Miconazole in effectiveness. It inhibits Candida albicans strains with minimum inhibitory concentration (MIC) values ranging from 0.06 to 8 μg/mL [1].
价 格:¥电议型 号:T75181产 地:中国大陆