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T7016VR23Apoptosis,VR-23,VR23,Proteasome,inhibit,Inhibitor,VR 23
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.
价 格：￥电议型 号：T7016产 地：中国大陆
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T7535RGX-202cancer,apoptosis,inhibit,creatine import,RGX 202,RGX-202,Inhibitor,oral,RGX202,mice,Endogenou
3-Guanidinopropionic acid is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARγ coactivator 1α (PGC-1α).
价 格：￥电议型 号：T7535产 地：中国大陆
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T6630Quercetin DihydrateInhibitor,PI3K,Phosphoinositide 3-kinase,Quercetin Dihydrate,Apoptosis,inhibit
Quercetin is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effects.
价 格：￥电议型 号：T6630产 地：中国大陆
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T6855HA15HA-15,HSP,HA 15,Inhibitor,HA15,Apoptosis,inhibit,Autophagy,Heat shock proteins
HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
价 格：￥电议型 号：T6855产 地：中国大陆
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T6800CCF642calcium,Inhibitor,PDI,CCF642,apoptosis,isomerases,disulfide,myeloma,CCF-642,protein,multiple,r
CCF642 is a novel PDI-inhibiting compound with antimyeloma activity.
价 格：￥电议型 号：T6800产 地：中国大陆
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T9014SKI-178resistant,SphK,cytotoxic,myeloid,Inhibitor,Apoptosis,leukemia,multi-drug,inhibit,SKI-178,canc
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during prolonged mitosis, mediated by SKI-178 leads to the simultaneous phosphorylation of the prosurvival Bcl-2 family members, Bcl-2 and Bcl-xl, as well as the phosphorylation and subsequent degradation of Mcl-1.
价 格：￥电议型 号：T9014产 地：中国大陆
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T7398ONC212ONC212,ONC-212,Inhibitor,ONC 212,inhibit,Apoptosis
ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.
价 格：￥电议型 号：T7398产 地：中国大陆
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T6432CalpeptinCathepsin,Apoptosis,inhibit,Calpeptin,Inhibitor,Proteasome
Calpeptin is a potent, cell-permeable calpain inhibitor.
价 格：￥电议型 号：T6432产 地：中国大陆
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T6584MG 149HAT,Inhibitor,MG 149,Epigenetic Reader Domain,Apoptosis,HATs,inhibit,Histone Acetyltransferase
MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).
价 格：￥电议型 号：T6584产 地：中国大陆
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TL0006Cichoric Acidp-Akt,inhibit,ROS,anti-inflammatory,Apoptosis,glucose uptake,insulin resistance,glucosa
Chicoric Acid is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and independent.
价 格：￥电议型 号：TL0006产 地：中国大陆
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T79792-Hydroxychalconeinhibit,Inhibitor,Apoptosis,Nuclear factor-κB,Nuclear factor-kappaB,NF-κB,TNBC,2 Hy
2-Hydroxychalcone can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breast cancer cells.
价 格：￥电议型 号：T7979产 地：中国大陆
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T8461SKI VPI3K,SKI V,Inhibitor,Apoptosis,GST-hSK,sphingosine,second,mitogenic,Phosphoinositide 3-kinase,S
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces apoptosis and has antitumor activity
价 格：￥电议型 号：T8461产 地：中国大陆
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TWS2045Bruceine DParasite,Notch,Apoptosis,Bruceine D,Inhibitor,inhibit
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW199 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
价 格：￥电议型 号：TWS2045产 地：中国大陆
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T8478SC-43antiproliferative,Inhibitor,SC-43,SHP-1,PTPN6,Phosphatase,Apoptosis,caspase-3,SC 43,anti-fibrot
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
价 格：￥电议型 号：T8478产 地：中国大陆
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T8678NaphthazarinNaturally,Apoptosis,Naphthazarin,stress,microtubules,mitochondrial,AIF,Inhibitor,p21,lys
Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. It triggers apoptosis and has anti-tumor effects
价 格：￥电议型 号：T8678产 地：中国大陆
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T6S0139Neobavaisoflavoneflavonoid,corylifolia,Neobavaisoflavone,anti-oxidation,polymerase,Apoptosis,anti-ca
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can significantly inhibit the production of reactive oxygen species (ROS), reactive nitrogen species (RNS) and cytokines: IL-1β, IL-6, IL-12p4, IL-12p7, TNF-α in LPS+IFN-γ- or PMA- stimulated RAW264.7 macrophages.
价 格：￥电议型 号：T6S0139产 地：中国大陆
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TN1153Polyporenic acid Ccell,Apoptosis,inhibit,Inhibitor,lung,cancer,NSCLC,Polyporenic acid C
Polyporenic acid C shows inhibitory activity against human collagenase.
价 格：￥电议型 号：TN1153产 地：中国大陆
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T8206Cycleaninecalcium,Calcium Channel,ICaL,anti-ovarian,Apoptosis,Ca2+ channels,Cycleanine,Ca channels,V
Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.
价 格：￥电议型 号：T8206产 地：中国大陆
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T6967RHPS4HT29,RHPS 4,Telomerase,RHPS-4,breast,Apoptosis,cancer,Inhibitor,inhibit,M14,RHPS4,PC3,H460,H2AX
RHPS4 is a potent inhibitor of Telomerase at submicromolar.
价 格：￥电议型 号：T6967产 地：中国大陆
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T6S1141Ganoderic acid AInhibitor,Autophagy,Ganoderic acid A,Apoptosis,inhibit,Endogenous Metabolite
1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly su
价 格：￥电议型 号：T6S1141产 地：中国大陆
