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  • T78828AChE/BChE-IN-15；化合物 AChE/BChE-IN-15AChE/BChE-IN-15

    AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (IC50) of 20 nM for AChE and 220 nM for BChE. It interacts with the catalytic anionic site (CAS) and the peripheral anionic site (PAS) within the enzymes´ active sites. AChE/BChE-IN-15 is applicable in Alzheimer’s disease research [1].

    价 格：￥电议型 号：T78828产 地：中国大陆

  • T78799BChE/HDAC6-IN-1；化合物 BChE/HDAC6-IN-1BChE/HDAC6-IN-1

    BChE/HDAC6-IN-1 is a dual BChE/HDAC6 inhibitor that exhibits potent and selective inhibition with IC50 values of 4 nM for BChE and 8.9 nM for HDAC6. It demonstrates efficacy in alleviating cognitive deficits in an Aβ1–42-induced mouse model, indicating its potential utility in Alzheimer´s disease research [1].

    价 格：￥电议型 号：T78799产 地：中国大陆

  • T78695BChE-IN-16；化合物 BChE-IN-16BChE-IN-16

    BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM. It demonstrates low cytotoxicity and potential for central nervous system (CNS) permeability, along with unique adaptability, rendering it a valuable tool for research into Alzheimer´s disease (AD).

    价 格：￥电议型 号：T78695产 地：中国大陆

  • T76830Teneliximab；化合物TeneliximabChi220|||Anti-Human CD40 Recombinant Antibody|||BMS 224819；Chi220|||Anti-H

    Teneliximab (Chi220) is a chimeric monoclonal antibody and a tumor necrosis factor receptor superfamily member 5 (CD40) inhibitor that blocks CD40-CD40L interactions.Teneliximab exerts partial agonist activity through CD40 and peripheral B-cell depletion, and may be used to study organ transplant rejection and rheumatoid arthritis.

    价 格：￥电议型 号：T76830产 地：中国大陆

  • T75561Chloranthalactone B；化合物 Chloranthalactone BChloranthalactone B

    Chloranthalactone B, a lindenane-type sesquiterpenoid derived from the Chinese medicinal herb Sarcandra glabra, acts as an inhibitor of inflammatory mediator production through the suppression of the AP-1 and p38 MAPK pathways [1].

    价 格：￥电议型 号：T75561产 地：中国大陆

  • T75544AChE/BChE-IN-11；化合物 AChE/BChE-IN-11AChE/BChE-IN-11

    AChE/BChE-IN-11 (compound 1), a natural product derived from artichoke leaves, is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 70 μM for AChE and 71 μM for BChE, respectively. This compound is utilized in the research of Alzheimer’s disease (AD) [1].

    价 格：￥电议型 号：T75544产 地：中国大陆

  • T75513BChE-IN-12；化合物 BChE-IN-12BChE-IN-12

    BChE-IN-12, also known as compound 12, is a potent non-competitive inhibitor of butyrylcholinesterase (BChE) with an IC50 value of 2.3 μM. Derived from Bletilla striata, it is utilised in research related to Alzheimer´s disease (AD) [1].

    价 格：￥电议型 号：T75513产 地：中国大陆

  • T75511BChE-IN-10；化合物 BChE-IN-10BChE-IN-10

    BChE-IN-10 (compound 6), isolated from Bletilla striata, is a potent mixed-type butyrylcholinesterase (BChE) inhibitor exhibiting an IC50 value of 6.4 μM. It is utilized in Alzheimer´s disease (AD) research [1].

    价 格：￥电议型 号：T75511产 地：中国大陆

  • T75471Chetoseminudin B；化合物 Chetoseminudin BChetoseminudin B

    Chetoseminudin B exhibits inhibitory activity against mushroom tyrosinase, with an IC 50 value of 31.7 μM [1].

    价 格：￥电议型 号：T75471产 地：中国大陆

  • T74812hBChE-IN-1；化合物 hBChE-IN-1hBChE-IN-1

    hBChE-IN-1 (compound 4), a quinolizidinyl derivative, effectively inhibits human Butyrylcholinesterase (hBChE) with an IC50 value of 7 nM, demonstrating high selectivity against human Acetylcholinesterase (hAChE). It also possesses inhibitory properties against tau and Aβ 40 protein aggregation, exhibiting IC50 values of 20 and 4.3 μM, respectively, making it a valuable asset for Alzheimer´s disease research [1].

    价 格：￥电议型 号：T74812产 地：中国大陆

  • T73202BChE-IN-11；化合物 BChE-IN-11BChE-IN-11

    BChE-IN-11, a selective and non-competitive inhibitor of butyrylcholinesterase (BChE), demonstrates potent activity with an inhibitory concentration (IC50) of 2.1 μM. This compound is applicable in Alzheimer´s disease (AD) research.

    价 格：￥电议型 号：T73202产 地：中国大陆

  • T73184BChE-IN-15；化合物 BChE-IN-15BChE-IN-15

    BChE-IN-15 is a compound characterized as a pseudo-irreversible, covalent inhibitor of butyrylcholinesterase (BChE), demonstrating potent activity with an inhibitory concentration (IC50) of 1.76 nM against human BChE (hBChE).

    价 格：￥电议型 号：T73184产 地：中国大陆

  • T72454AChE/BChE/MAO-B-IN-4；化合物 AChE/BChE/MAO-B-IN-4AChE/BChE/MAO-B-IN-4

    AChE/BChE/MAO-B-IN-4, an indan-1-one derivative, serves as a potent inhibitor for both monoamine oxidase B (MAO-B) and acetylcholinesterase/butyrylcholinesterase (AChE/BChE) enzymes. It exhibits a strong inhibitory effect on human MAO-B with an IC50 of 0.0393 μM, and demonstrates significant potency against human AChE and BChE enzymes with IC50 values of 0.0458 μM and 0.075 μM, respectively. Additionally, this compound displays notable antioxidant properties and the ability to prevent β-amyloid

    价 格：￥电议型 号：T72454产 地：中国大陆

  • T72453AChE/BChE/MAO-B-IN-3；化合物 AChE/BChE/MAO-B-IN-3AChE/BChE/MAO-B-IN-3

    AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, serves as a potent inhibitor of human monoamine oxidase B (MAO-B) with an IC50 of 0.0359 μM, demonstrating significant inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 0.0473 μM and 0.0782 μM, respectively. Exhibiting notable antioxidant activity, AChE/BChE/MAO-B-IN-3 holds considerable promise for Alzheimer´s disease (AD) research.

    价 格：￥电议型 号：T72453产 地：中国大陆

  • T72452AChE/BChE/MAO-B-IN-2；化合物 AChE/BChE/MAO-B-IN-2AChE/BChE/MAO-B-IN-2

    AChE/BChE/MAO-B-IN-2 is a potent inhibitor of the enzymes AChE, BChE, and MAO-B, with IC50 values of 48.2 nM, 83.9 nM, and 31.2 nM, respectively. It exhibits significant antioxidant activity and is applicable in Parkinson’s disease research.

    价 格：￥电议型 号：T72452产 地：中国大陆

  • T64156AChE/BChE-IN-1；化合物 AChE/BChE-IN-1AChE/BChE-IN-1

    AChE/BChE-IN-1 is a potent dual inhibitor of acetylcholinesterase and butyrylcholinesterase with blood-brain barrier permeability, exhibiting an IC50 value of 1.06 and 7.3 nM for hAChE and hBChE, respectively, and showing antioxidant effects. AChE/BChE-IN-1 can be used in Alzheimer´s disease research.

    价 格：￥电议型 号：T64156产 地：中国大陆

  • T63091BChE-IN-5；化合物 BChE-IN-5BChE-IN-5

    BChE-IN-5 is a potent and selective inhibitor of BChE (IC50: 2.8 nM) and has a higher inhibitory effect on hBChE than hAChE. BChE-IN-5 has potential for use in Alzheimer´s disease research.

    价 格：￥电议型 号：T63091产 地：中国大陆

  • T62565BChE-IN-9；化合物 BChE-IN-9BChE-IN-9

    BChE-IN-9 (Azepano-11-deoxo-glycyrrhetol) is a hybrid BChE inhibitor (Ki: 0.21 μM).

    价 格：￥电议型 号：T62565产 地：中国大陆

  • T62504BChE-IN-8；化合物 BChE-IN-8BChE-IN-8

    BChE-IN-8 (compound 20) is an orally active BChE (butyrylcholinesterase) inhibitor that crosses the blood-brain barrier and acts on eqBChE (IC50: 0.15 nM), hBChE (IC50: 45.2 nM). BChE-IN-8 can be used in the study of Alzheimer´s disease (AD), where it can exert neuroprotective and cognitive improvement effects through a variety of regulatory mechanisms, including the cholinergic system, Aβ aggregation and neuropeptide levels.

    价 格：￥电议型 号：T62504产 地：中国大陆

  • T62336BChE-IN-3；化合物 BChE-IN-3BChE-IN-3

    BChE-IN-3 is a selective, selective, time-dependent, pseudo-irreversible inhibitor of BChE butyrylcholinesterase (IC50: 56.9 nM).BChE-IN-3 exhibits borderline reversible (time-independent) inhibition of AChE acetylcholinesterase.

    价 格：￥电议型 号：T62336产 地：中国大陆

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