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T1927CCT007093CCT007093
CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).
价 格：￥电议型 号：T1927产 地：美洲
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T78177CCT374705；化合物 CCT374705CCT374705
CCT374705, an orally active BCL6 inhibitor, exhibits potent antiproliferative effects in vitro and effectively inhibits tumor growth in a lymphoma xenograft mouse model [1].
价 格：￥电议型 号：T78177产 地：中国大陆
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T77915CCT367766 formic；化合物 CCT367766 formicCCT367766 formic
CCT367766 formic is a potent third-generation heterobifunctional Cereblon-based protein degradation probe (PDP, or PROTAC) that selectively targets pirin for degradation, effectively diminishing its protein expression at low concentrations. This compound demonstrates moderate affinity towards the CRBN-DDB1 complex, as denoted by an IC50 value of 490 nM, while exhibiting strong binding to recombinant pirin and CRBN, with respective Kd values of 55 nM and 120 nM. As such, CCT367766 formic serves a
价 格：￥电议型 号：T77915产 地：中国大陆
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T71353CCT239065；化合物 CCT239065CCT239065
CCT239065 is a novel, selective, and efficacious nanomolar pyridopyrazinone V600EBRAF and LCK inhibitor.
价 格：￥电议型 号：T71353产 地：中国大陆
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T7080CCT245737；化合物CCT245737SRA737；SRA737
CCT245737 (SRA737) is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50: 2440 nM).
价 格：￥电议型 号：T7080产 地：中国大陆
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T70553CCT245737(S)；化合物 CCT245737(S)CCT245737(S)
CCT245737(S) is a highly selective oral checkpoint kinase 1 (CHK1) inhibitor.
价 格：￥电议型 号：T70553产 地：中国大陆
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T70387CCCTP；化合物 CCCTPCCCTP
CCCTP is a potent inhibitor of the 11β-HSD-1 enzyme with reduced pregnane-X receptor (PXR) transactivation activity.
价 格：￥电议型 号：T70387产 地：中国大陆
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T68913CCT068127；化合物 CCT068127CCT068127
CCT068127 is a potent CDK2 and CDK9 inhibitor.
价 格：￥电议型 号：T68913产 地：中国大陆
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T6435CCT129202化合物CCT1292022-[4-[6-氯-2-(4-二甲基氨基苯基)-3H-咪唑并[4,5-B]吡啶-7-基]哌嗪-1-基]-N-(噻唑-2-基)乙酰胺
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.
价 格：￥电议型 号：T6435产 地：中国大陆
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T63862CCT373567；化合物 CCT373567CCT373567
CCT373567 is a potent degrader of the transcriptional repressor BCL6 (IC50: 2.9 nM) and exhibits anti-proliferative effects.
价 格：￥电议型 号：T63862产 地：中国大陆
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T63861CCT373566；化合物 CCT373566CCT373566
CCT373566 is a potent, orally active degrader of the transcriptional repressor BCL6 (IC50: 2.2 nM). CCT373566 exhibits significant anti-proliferative effects in vitro and reduces tumour growth in vivo.
价 格：￥电议型 号：T63861产 地：中国大陆
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T63503CCT369260；化合物 CCT369260CCT369260
CCT369260 (compound 1), an orally active inhibitor targeting B-cell lymphoma 6 (BCL6), demonstrates anti-tumor efficacy with an IC50 value of 520 nM [1].
价 格：￥电议型 号：T63503产 地：中国大陆
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T6303LCCT128930 hydrochloride；化合物CCT128930 hydrochlorideCCT128930 hydrochloride(885499-61-6 Free base)；CCT
CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50: 168 nM) through the targeting of Met282 of AKT, as well as 20-fold selectivity over p70S6K (IC50: 120 nM).
价 格：￥电议型 号：T6303L产 地：中国大陆
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T6303CCT128930；化合物CCT128930CCT128930
CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.
价 格：￥电议型 号：T6303产 地：中国大陆
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T62775CCT245232；化合物 CCT245232CCT245232
CCT245232 is a potent inhibitor of heat-stimulated factor 1 (HSF1). CCT245232 has the potential to be used in studies of proliferative diseases such as cancer.
价 格：￥电议型 号：T62775产 地：中国大陆
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T4428CCT241736；化合物CCT241736CCT241736
CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3, CCT241736, an advanced analog of CCT137690, is a preclinical development candidate for the treatment of human malignancies, and in particular AML in adults and children.
价 格：￥电议型 号：T4428产 地：中国大陆
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T4133CCT196969；化合物CCT196969CCT196969
CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.
价 格：￥电议型 号：T4133产 地：中国大陆
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T36704CCT241533 dihydrochloride；CCT 241533 dihydrochlorideCCT 241533 dihydrochloride；CCT 241533 dihydrochl
Potent Chk2 inhibitor (IC50 = 3 nM). Shows >63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide-induced DNA damage in HT29 cells. Blocks ionizing radiation-induced apoptosis of mouse thymocytes.
价 格：￥电议型 号：T36704产 地：中国大陆
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T3454VER-49009；化合物VER-49009CCT 129397；CCT 129397
VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).
价 格：￥电议型 号：T3454产 地：中国大陆
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T28498Lrac-CCT-250863 HCl；化合物rac-CCT-250863盐酸盐rac-CCT-250863 HCl(1364269-06-6 Free base)；rac-CCT-250863 HCl
rac-CCT-250863 HCl is a selective and reversible inhibitor of NEK 2. rac-CCT-250863 HCl induces cell cycle arrest and has good anti-proliferative activity against cancer cells. rac-CCT-250863 HCl can be used in combination with Pomalidomide to induce apoptosis and can be used in combined anti-cancer studies.
价 格：￥电议型 号：T28498L产 地：中国大陆
