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T74852PROTAC CDK9 degrader-6；化合物 PROTAC CDK9 degrader-6PROTAC CDK9 degrader-6
PROTAC CDK9 degrader-6 is a specific PROTAC targeting CDK9 that mediates its degradation through the proteasome pathway. This compound effectively degrades CDK9 with DC50 values of 0.10 μM and 0.14 μM for the CDK9 42 and CDK9 55 isoforms, respectively [1].
价 格：￥电议型 号：T74852产 地：中国大陆
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T74851PROTAC CDK9 degrader-5；化合物 PROTAC CDK9 degrader-5PROTAC CDK9 degrader-5
PROTAC CDK9 degrader-5 is a selective PROTAC that mediates degradation of CDK9 via the proteasome pathway. It efficiently degrades the CDK9 42 and CDK9 55 isoforms with DC50 values of 0.10 μM and 0.14 μM, respectively [1].
价 格：￥电议型 号：T74851产 地：中国大陆
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T74707PROTAC FLT3/CDK9 degrader-1；化合物 PROTAC FLT3/CDK9 degrader-1PROTAC FLT3/CDK9 degrader-1
PROTAC FLT3/CDK9 degrader-1, a potent dual degrader of FLT3 and CDK9, effectively induces apoptosis and targets protein degradation of FLT3 and CDK9. This compound holds research potential for FLT3-ITD mutated AML [1].
价 格：￥电议型 号：T74707产 地：中国大陆
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T70400CDK9/CycT1-IN-93；化合物 CDK9/CycT1-IN-93CDK9/CycT1-IN-93
CDK9/CycT1-IN-93 is a highly specific, ATP-competitive inhibitor of CDK9/CycT1 with antiviral activity.
价 格：￥电议型 号：T70400产 地：中国大陆
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T63851CDK9/10/GSK3β-IN-1；化合物 CDK9/10/GSK3β-IN-1CDK9/10/GSK3β-IN-1
CDK9/10/GSK3β-IN-1 is a kinase inhibitor (Flavopiridol analogue) that effectively inhibits HsGSK3β, HsCDK9/CyclinT, HsCDK5/p25 and HsCDK2/CyclinA with IC50 values of 59 nM, 64 nM, 1.093 μM and 1.725 μM, respectively. CDK9/10/GSK3β-IN-1 exhibited comparable or higher anti-cancer cell activity than Flavopiridol and showed high anti-proliferative activity against up to seven cancer cell lines in vitro.
价 格：￥电议型 号：T63851产 地：中国大陆
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T63490CDK9-IN-19；化合物 CDK9-IN-19CDK9-IN-19
CDK9-IN-19 is a selective and potent CDK9 inhibitor (IC50: 2.0 nM). CDK9-IN-19 exhibits good anti-proliferative activity in cancer cells, moderate pharmacokinetic properties and low hERG inhibition. CDK9-IN-19 significantly inhibited tumor growth in the MV4-11 xenograft mouse model. CDK9-IN-19 can be used in studies of acute myeloid leukemia (AML).
价 格：￥电议型 号：T63490产 地：中国大陆
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T63357EGFR/HER2/CDK9-IN-2；化合物 EGFR/HER2/CDK9-IN-2EGFR/HER2/CDK9-IN-2
EGFR/HER2/CDK9-IN-2 are potent inhibitors of EGFR/HER2/CDK9, and they exhibited significant antitumor effects with IC50s of 145.35, 129.07 and 117.13 nM, respectively.
价 格：￥电议型 号：T63357产 地：中国大陆
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T63161EGFR/HER2/CDK9-IN-3；化合物 EGFR/HER2/CDK9-IN-3EGFR/HER2/CDK9-IN-3
EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR (IC50:191.08 nM), HER2 (IC50:132.65 nM), and CDK9 (IC50:113.98 nM). EGFR/HER2/CDK9-IN-3 showed significant anti-tumor effects.
价 格：￥电议型 号：T63161产 地：中国大陆
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T63054CDK9-IN-18；化合物 CDK9-IN-18CDK9-IN-18
CDK9-IN-18 is a potent inhibitor of CDK9 that blocks the phosphorylation of the kinase CDK9. CDK9-IN-18 exhibits good anticancer activity and low cellular activity and is able to induce apoptosis.
价 格：￥电议型 号：T63054产 地：中国大陆
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T62919CDK9-IN-13；化合物 CDK9-IN-13CDK9-IN-13
CDK9-IN-13 is a potent and selective CDK inhibitor (IC50<3 nM). CDK9-IN-13 has a very short half-life in rodents.
价 格：￥电议型 号：T62919产 地：中国大陆
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T62746EGFR/HER2/CDK9-IN-1；化合物 EGFR/HER2/CDK9-IN-1EGFR/HER2/CDK9-IN-1
EGFR/HER2/CDK9-IN-1 (Compound 4) is a potent EGFR/HER2/CDK9 inhibitor with IC50 values of 90.17, 131.39 and 67.04 nM. EGFR/HER2/CDK9-IN-1 exhibits significant anti-tumour effects.
价 格：￥电议型 号：T62746产 地：中国大陆
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T62203CDK9-IN-14；化合物 CDK9-IN-14CDK9-IN-14
CDK9-IN-14 is a potent, high and low selective CDK9 inhibitor (IC50: 6.92 nM). CDK9-IN-14 is a strong inhibitor of MV-4-11 cells and in vivo tumour models with low toxicity and few side effects.
价 格：￥电议型 号：T62203产 地：中国大陆
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T60619CDK9-IN-15；化合物CDK9-IN-15CDK9-IN-15
CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CDK9, inhibit transcription, and rapidly reduce the level of intracellular mRNA, thereby causing apoptosis of tumor cells.
价 格：￥电议型 号：T60619产 地：中国大陆
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T5438PROTAC CDK9 Degrader-1；化合物PROTAC CDK9 Degrader-1PROTAC CDK9 Degrader-1
PROTAC CDK9 Degrader-1 is a selective CDK9 degrader.
价 格：￥电议型 号：T5438产 地：中国大陆
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T39997PROTAC CDK9 ligand-1；PROTAC CDK9 ligand-1PROTAC CDK9 ligand-1；PROTAC CDK9 ligand-1
PROTAC CDK9 ligand-1 is a CDK9 ligand that can be used in the synthesis of PROTACs.
价 格：￥电议型 号：T39997产 地：中国大陆
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T39996PROTAC CDK9 degrader-4；PROTAC CDK9 degrader-4PROTAC CDK9 degrader-4；PROTAC CDK9 degrader-4
PROTAC CDK9 degrader-4 is a potent and efficacious chemical compound designed specifically to degrade CDK9, a protein involved in transcription regulation. This compound effectively targets and reduces the levels of CDK9, thereby modulating transcriptional activity.
价 格：￥电议型 号：T39996产 地：中国大陆
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T39354CDK9-IN-12CDK9-IN-12CDK9-IN-12
CDK9-IN-12 displays the optimal CDK9 inhibitory activity with an IC 50 value of 5.41 nM.
价 格：￥电议型 号：T39354产 地：中国大陆
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T36744CDK9 Antagonist-1；CDK9 Antagonist-1CDK9 Antagonist-1；CDK9 Antagonist-1
CDK9 Antagonist-1 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1].
价 格：￥电议型 号：T36744产 地：中国大陆
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T17728PROTAC CDK9 degrader-2；化合物 T17728PROTAC CDK9 degrader-2
PROTAC CDK9 degrader-2 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1].
价 格：￥电议型 号：T17728产 地：中国大陆
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T118066CDK9 inhibitor HH1；化合物CDK9 inhibitor HH18019-9719；8019-9719
CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.
价 格：￥电议型 号：T118066产 地：中国大陆
