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T61719DC-CPin711;化合物 DC-CPin711DC-CPin711
DC-CPin711, a potent and selective inhibitor of the bromodomain of CREB-binding protein (CBP) with an IC50 of 0.0626 μM, effectively halts the cell cycle at the G1 phase and promotes apoptosis [1].
价 格:¥电议型 号:T61719产 地:中国大陆
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T6157Devimistat;辛酸CPI-613|||CPI613|||CPI 613|||6,8-Bis(benzylthio)octanoic acid;CPI-613|||辛酸|||CPI613|||C
Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potential chemopreventive and antineoplastic activities, and has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Advanced Cancer, and Pancreatic Cancer, among others.
价 格:¥电议型 号:T6157产 地:中国大陆
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T61314DC-CPin7;化合物 DC-CPin7DC-CPin7
DC-CPin7, a powerful inhibitor of the bromodomain of CREB-binding protein (CBP), exhibits an IC50 value of 2.5 μM [1].
价 格:¥电议型 号:T61314产 地:中国大陆
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T6026CPI-203化合物CPI203CPI 203|||CPI203
CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).
价 格:¥电议型 号:T6026产 地:中国大陆
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T40199Tulmimetostat;化合物TulmimetostatCPI-0209;CPI-0209
Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advanced solid tumors.
价 格:¥电议型 号:T40199产 地:中国大陆
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T39971CPI-1328;CPI-1328CPI-1328
CPI-1328 is an EZH2 inhibitor with a K i value of 63 fM.
价 格:¥电议型 号:T39971产 地:中国大陆
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T39352Piperidine-GNE-049-N-Boc;Piperidine-GNE-049-N-BocPiperidine-GNE-049-N-Boc
Piperidine-GNE-049-N-Boc is a ligand that specifically binds to the target protein dCBP, enabling it to be degraded by a selective and potent heterobifunctional degrader, p300/CBP.
价 格:¥电议型 号:T39352产 地:中国大陆
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T38420GCPII-IN-1;GCPII-IN-1GCPII-IN-1
GCPII-IN-1 is a potent inhibitor scaffold targeting glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA). It exhibits a high affinity for GCPII, with a binding affinity (K i ) of 44.3 nanomolar (nM).
价 格:¥电议型 号:T38420产 地:中国大陆
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T37792A2A receptor antagonist 1;化合物A2A receptor antagonist 1CPI-444 analog|||A2A receptor antagonist 1;CPI
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.
价 格:¥电议型 号:T37792产 地:中国大陆
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T3576CPI-455 analogue;化合物 CPI-455 analogueCPI-455 analogue;CPI-455 analogue
CPI-455 analogue (CPI-455 analogue) is an analogue of CPI-455 which is a KDM5 inhibitor.
价 格:¥电议型 号:T3576产 地:中国大陆
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T3561CPI1189;化合物CPI1189CPI-1189|||REN-1189|||CPI 1189;CPI-1189|||REN-1189|||CPI 1189
CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
价 格:¥电议型 号:T3561产 地:中国大陆
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T3552CPI-455;化合物CPI455CPI-455 HCl;CPI-455 HCl
CPI-455 is a specific KDM5 inhibitor.
价 格:¥电议型 号:T3552产 地:中国大陆
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T32136ICT2700;化合物 T32136de OH CPI MI|||deOHCPIMI|||de-OH-CPI-MI|||ICT 2700|||ICT-2700;de OH CPI MI|||deOHC
ICT2700 is a potent cytotoxin selectively by CYP1A1 as a tumor-selective treatment for human bladder cancers.
价 格:¥电议型 号:T32136产 地:中国大陆
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T27074CPI-905;化合物 T27074CPI 905;CPI 905
CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.
价 格:¥电议型 号:T27074产 地:中国大陆
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T27073CPI-7c;化合物 T27073CPI 7c;CPI 7c
CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.
价 格:¥电议型 号:T27073产 地:中国大陆
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T27072CPI703;化合物 T27072CPI-703|||CPI 703;CPI-703|||CPI 703
CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.
价 格:¥电议型 号:T27072产 地:中国大陆
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T27071CPI571;化合物 T27071CPI571
CPI571 is a potent and selective inhibitor for the bromodomains of CREBBP/EP300.
价 格:¥电议型 号:T27071产 地:中国大陆
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T27070CPI-4203;化合物 T27070CPI4203|||CPI 4203;CPI4203|||CPI 4203
CPI-4203 is a selective inhibitor of KDM5 demethylases.
价 格:¥电议型 号:T27070产 地:中国大陆
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T27068CPI098;化合物 T27068CPI-098|||CPI 098;CPI-098|||CPI 098
CPI098 is a potent and selective inhibitors for the bromodomains of CREBBP/EP300. CREBBP/EP300 bromodomains play a critical role in regulatory T cell biology. T cell recruitment to tumors is a major mechanism of immune evasion by cancer cells.
价 格:¥电议型 号:T27068产 地:中国大陆
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T263884-CPI;化合物 T263884 CPI;4 CPI
4-CPI inhibits non-active site mutants of cytochrome P450 2B4.
价 格:¥电议型 号:T26388产 地:中国大陆