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  • T2002PF-4708671PF-4708671,PF4708671,PF 4708671

    PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays,PF-4708671 is potent for S6K1(Ki50=20 nM,IC50=160 nM).

    价 格：￥电议型 号：T2002产 地：美洲

  • T5056PF-4800567PF-4800567,PF4800567,PF 4800567

    PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.

    价 格：￥电议型 号：T5056产 地：美洲

  • T6028PF-477736PF-477736,PF477736,PF 477736

    PF-477736 is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.

    价 格：￥电议型 号：T6028产 地：美洲

  • T83935eIF4A i28；化合物 eIF4A i28eIF4A i28

    eIF4A i28, an inhibitor of the eukaryotic initiation factor-4A (eIF4A) with an IC50 of 8.60 μM in an eIF4A ATPase assay, effectively reduces the viability of BJAB Burkitt lymphoma cells, as indicated by an EC50 of 0.46 μM in a CellTiter-Glo (CTG) luminescence cell viability assay. This compound functions as an RNA-competitive, ATP-uncompetitive eIF4A inhibitor.

    价 格：￥电议型 号：T83935产 地：中国大陆

  • T82489eIF4E-IN-6；化合物 eIF4E-IN-6eIF4E-IN-6

    eIF4E-IN-6 (Compound 4b), a GMP analog, is designed to inhibit the eIF4E protein´s ability to bind to cap mRNA. It demonstrates cytotoxic effects on Caco-2, HepG-2, and MCF-7 cell lines with IC50 values of 31, 27, and 21 μM, respectively [1].

    价 格：￥电议型 号：T82489产 地：中国大陆

  • T79525eIF4E-IN-5；化合物 eIF4E-IN-5eIF4E-IN-5

    eIF4E-IN-5 (Compound 6n) is a cell-permeable eIF4E inhibitor that binds to capped mRNA, thereby inhibiting cap-dependent translation [1].

    价 格：￥电议型 号：T79525产 地：中国大陆

  • T78341Human IgG1 (F405L) kappa, Isotype Control；化合物 Human IgG1 (F405L) kappa, Isotype ControlHuman IgG1 (F

    Human IgG1 (F405L) kappa Isotype Control is a chimeric human-mouse monoclonal antibody serving as an isotype control for the human IgG1 (F405L)κ antibody.

    价 格：￥电议型 号：T78341产 地：中国大陆

  • T75380Rf470DL；化合物 Rf470DLRf470DL

    Rf470DL, a rotor-fluorogenic D-amino acid (RfDAA), serves as a bacterial labeling agent, exhibiting an excitation wavelength (Ex) of 470 nm and an emission wavelength (Em) of 640 nm [1].

    价 格：￥电议型 号：T75380产 地：中国大陆

  • T73001eIF4A3-IN-9；化合物 eIF4A3-IN-9eIF4A3-IN-9

    eIF4A3-IN-9, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 29, 450, and 80 nM for myc-LUC, tub-LUC, and growth inhibition in MBA-MB-231 cells, respectively. It is utilized in researching human cancer pathogenesis [1].

    价 格：￥电议型 号：T73001产 地：中国大陆

  • T72944eIF4A3-IN-18；化合物 eIF4A3-IN-18eIF4A3-IN-18

    eIF4A3-IN-18, a silvestrol analogue, disrupts the formation of the eIF4F translation complex, exhibiting EC 50 values of 0.8, 35, and 2 nM for myc-LUC, tub-LUC, and the growth inhibition of MBA-MB-231 cells, respectively. Additionally, it demonstrates cytotoxicity towards RMPI-8226 cells with an LC 50 of 0.06 nM. This compound is utilized in researching human cancer pathogenesis [1].

    价 格：￥电议型 号：T72944产 地：中国大陆

  • T72943eIF4A3-IN-17；化合物 eIF4A3-IN-17eIF4A3-IN-17

    eIF4A3-IN-17, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 0.9, 15, and 1.8 nM for myc-LUC, tub-LUC, and growth inhibition of MBA-MB-231 cells, respectively. This compound holds potential for research in human cancer pathogenesis [1].

    价 格：￥电议型 号：T72943产 地：中国大陆

  • T72746(R)-eIF4A3-IN-2；化合物 (R)-eIF4A3-IN-2(R)-eIF4A3-IN-2

    (R)-eIF4A3-IN-2, a less active enantiomer of eIF4A3-IN-2, is a highly selective and noncompetitive inhibitor of the eukaryotic initiation factor 4A-3 (eIF4A3) with an IC50 of 110 nM.

    价 格：￥电议型 号：T72746产 地：中国大陆

  • T68042CHF-4227；化合物Chf4227Chf4227|||Chf 4227；Chf4227|||Chf 4227

    CHF-4227 is a novel, potent and selective estrogen receptor modulator that reduces cholesterol and LDL cholesterol concentrations.

    价 格：￥电议型 号：T68042产 地：中国大陆

  • T64337PF-04745637；化合物PF-04745637PF4745637|||PF 4745637|||PF 04745637|||PF-4745637；PF4745637|||PF 4745637||

    PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].

    价 格：￥电议型 号：T64337产 地：中国大陆

  • T62884eIF4A3-IN-6；化合物 eIF4A3-IN-6eIF4A3-IN-6

    eIF4A3-IN-6 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A) (e.g. eIF4AI and eIF4AII). eIF4A3-IN-6 has the potential to be investigated in eIF4A-dependent diseases, including cancer.

    价 格：￥电议型 号：T62884产 地：中国大陆

  • T6251PF-04691502；化合物PF04691502PF4691502；PF4691502

    PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.

    价 格：￥电议型 号：T6251产 地：中国大陆

  • T62161eIF4A3-IN-4；化合物 eIF4A3-IN-4eIF4A3-IN-4

    eIF4A3-IN-4 is a novel inhibitor of eIF4A (IC50: 8.6 μM).

    价 格：￥电议型 号：T62161产 地：中国大陆

  • T6028PF 477736；化合物PF477736PF 00477736|||PF-477736|||PF-736,PF-00477736|||PF477736；PF 00477736|||PF-477736

    PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.

    价 格：￥电议型 号：T6028产 地：中国大陆

  • T4385PF-4840154；化合物PF4840154PF-4840154

    PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel and elicited TrpA1-mediated nocifensive behaviour in mouse, with EC50 of 97 nM and 23 nM for rTrpA1 and hTrpA1, respectively.

    价 格：￥电议型 号：T4385产 地：中国大陆

  • T40214eIF4E-IN-2eIF4E-IN-2eIF4E-IN-2

    eIF4E-IN-2 is a highly effective inhibitor of eukaryotic initiation factor 4e (eIF4e). This compound exhibits significant potential in the investigation of eIF4e dependent diseases, particularly in the context of cancer research.

    价 格：￥电议型 号：T40214产 地：中国大陆

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