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T1803GNF-5GNF-5,GNF5,GNF 5
GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic properties.
价 格:¥电议型 号:T1803产 地:美洲
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T2262CHF5074CHF5074,CSP-1103,Itanapraced
CHF5074, a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).
价 格:¥电议型 号:T2262产 地:美洲
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T2465PF-562271PF-562271,PF562271,PF 562271
PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
价 格:¥电议型 号:T2465产 地:美洲
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T6085PF-543PF-543,PF543,PF 543
PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
价 格:¥电议型 号:T6085产 地:美洲
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T6097GNF-5837GNF-5837,GNF5837,GNF 5837
GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).
价 格:¥电议型 号:T6097产 地:美洲
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T8499eCF506;化合物eCF506eCF506
eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)
价 格:¥电议型 号:T8499产 地:中国大陆
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T82016Janelia Fluor? 526, SE;化合物 Janelia Fluor? 526, SEJF526, SE|||JF526, NHS;JF526, SE|||JF526, NHS
Janelia Fluor 526, SE (JF526, SE) is a fluorogenic yellow fluorescent dye featuring an NHS ester group. It serves as a versatile scaffold for creating fluorogenic ligands, suitable for labeling genetically encoded self-labeling protein tags and staining endogenous structures [1].
价 格:¥电议型 号:T82016产 地:中国大陆
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T82015Janelia Fluor? 549, Azide;化合物 Janelia Fluor? 549, AzideJF549, Azide;JF549, Azide
Janelia Fluor? 549, Azide (JF549, Azide) is a fluorescent dye characterized by an absorption maximum (λab (max)) of 549 nm and an emission maximum (λem (max)) of 571 nm.
价 格:¥电议型 号:T82015产 地:中国大陆
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T82014Janelia Fluor? 549, Maleimide TFA;化合物 Janelia Fluor? 549, Maleimide TFAJF549, Maleimide TFA;JF549, M
Janelia Fluor? 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye featuring an absorption maximum (λab (max)) at 549 nm and an emission maximum (λem (max)) at 571 nm [1].
价 格:¥电议型 号:T82014产 地:中国大陆
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T82013Janelia Fluor? 549, Tetrazine;化合物 Janelia Fluor? 549, TetrazineJF549, Tetrazine;JF549, Tetrazine
Janelia Fluor? 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye characterized by an absorption maximum (λab (max)) at 549 nm and an emission maximum (λem (max)) at 571 nm [1].
价 格:¥电议型 号:T82013产 地:中国大陆
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T81849MAT-POS-e194df51-1;化合物 MAT-POS-e194df51-1MAT-POS-e194df51-1
MAT-POS-e194df51-1 is an orally active, non-covalent, non-peptide inhibitor of the SARS-CoV-2 main protease (M^pro) with an IC_50 of 37nM. It exhibits cytotoxicity, with EC_50 values of 64nM in A549-ACE2-TMPRSS2 cells and 126nM in HeLa-ACE2 cells [1].
价 格:¥电议型 号:T81849产 地:中国大陆
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T78394Janelia Fluor? 525, SE;化合物 Janelia Fluor? 525, SEJF525, NHS|||JF525, SE;JF525, NHS|||JF525, SE
Janelia Fluor 525, SE (JF525, SE) is a yellow fluorescent dye with an excitation wavelength of 525 nm and an emission wavelength of 549 nm [1].
价 格:¥电议型 号:T78394产 地:中国大陆
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T78079NF546 hydrate;化合物 NF546 hydrateNF546 hydrate
NF546 (hydrate), a selective non-nucleotide P2Y11 agonist, exhibits a pEC50 value of 6.27 and induces interleukin-8 secretion from human monocyte-derived dendritic cells [1].
价 格:¥电议型 号:T78079产 地:中国大陆
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T77727Feeblin;IRF5抑制剂5IRF5-IN-1;IRF5-IN-1
Feeblin(IRF5-IN-1) is a protein degradation inducer that specifically blocks pro-inflammatory signaling pathways associated with autoimmune diseases and can be used to study immune system disorders in the class of systemic lupus erythematosus.
价 格:¥电议型 号:T77727产 地:中国大陆
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T76659Acetyl-PHF5 amide;化合物 Acetyl-PHF5 amideAcetyl-PHF5 amide
Acetyl-PHF5 amide is a tau peptide with amyloidogenic properties. It can undergo polymerization to form filamentous structures [1].
价 格:¥电议型 号:T76659产 地:中国大陆
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T765132F5 epitope;化合物 2F5 epitope2F5 epitope
The 2F5 epitope, a peptide gp41 (659-671), encompasses the complete sequential epitope recognized by one of the three broadly neutralizing antibodies against a wide range of primary HIV-1 isolates. This epitope is uniquely sequential and is identified by the 2F5 antibodies [1] [2].
价 格:¥电议型 号:T76513产 地:中国大陆
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T75383Anti-α-Tubulin Antibody, AF555 conjugate;化合物 Anti-α-Tubulin Antibody, AF555 conjugateAnti-α-Tubulin
Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for the specific detection of tubulin (Ex/Em: 554/567 nm) [1].
价 格:¥电议型 号:T75383产 地:中国大陆
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T71890F5446;化合物 F5446F5446
F5446 is a SUV39H1 inhibitor. F5446 has an EC50 of 0.496 μmol/L for SUV39H1 enzymatic activity. H3K9me3 was enriched in the promoters of GZMB, PRF1, FASLG, and IFNG in quiescent T cells. F5446 inhibited H3K9me3, thereby upregulating expression of these effectors in tumor-infiltrating CTLs and suppressing colon carcinoma growth in a CD8+ CTL-dependent manner in vivo. Our data indicate that SUV39H1 represses CTL effector gene expression and, in doing so, confers colon cancer immune escape.
价 格:¥电议型 号:T71890产 地:中国大陆
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T70719MLAF50;化合物 MLAF50MLAF50
MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.
价 格:¥电议型 号:T70719产 地:中国大陆
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T70338Lu AF58786;化合物 Lu AF58786Lu AF58786
Lu AF58786 is a novel potent and selective inhibitor of LRRK2, inhibiting LRRK2 WT, the overactive variant G2019S, and the resistant mutant A2016T56 at 12 nM, 19 nM and 93 nM, respectively.
价 格:¥电议型 号:T70338产 地:中国大陆