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  • T73142FLT3-IN-18；化合物 FLT3-IN-18FLT3-IN-18

    FLT3-IN-18, a potent and selective FLT3 inhibitor, exhibits an IC50 value of 0.003 μM. It effectively induces apoptosis and G1 phase cell cycle arrest, while inhibiting FLT3 and STAT5 phosphorylation. This compound holds potential for acute myeloid leukemia (AML) research.

    价 格：￥电议型 号：T73142产 地：中国大陆

  • T64104JAK2/FLT3-IN-1 TFA；化合物 JAK2/FLT3-IN-1 TFAJAK2/FLT3-IN-1 TFA

    JAK2/FLT3-IN-1 (TFA) is an orally active dual inhibitor of JAK2/FLT3 that exhibits anticancer effects, acting on JAK2 (IC50: 0.7 nM), FLT3 (IC50: 4 nM), JAK1 (IC50: 26 nM) and JAK3 (IC50: 39 nM).

    价 格：￥电议型 号：T64104产 地：中国大陆

  • T63629PDGFRα/FLT3-ITD-IN-2；化合物 PDGFRα/FLT3-ITD-IN-2PDGFRα/FLT3-ITD-IN-2

    PDGFRα/FLT3-ITD-IN-2 is a potent inhibitor of PDGFRα (IC50>20 μM) and FLT3 (IC50: 0.004 μM). PDGFRα/FLT3-ITD-IN-2 has shown investigational potential in acute myeloid leukemia or chronic eosinophilic leukemia.

    价 格：￥电议型 号：T63629产 地：中国大陆

  • T63454PDGFRα/FLT3-ITD-IN-1；化合物 PDGFRα/FLT3-ITD-IN-1PDGFRα/FLT3-ITD-IN-1

    PDGFRα/FLT3-ITD-IN-1 are potent inhibitors of PDGFRα/FLT3, and their IC50 values are greater than 0.036 and 0.003 μM, respectively. PDGFRα/FLT3-ITD-IN-1 exhibits investigational potential in acute myeloid leukemia or chronic eosinophilic leukemia.

    价 格：￥电议型 号：T63454产 地：中国大陆

  • T63274FLT3/ITD-IN-2；化合物 FLT3/ITD-IN-2FLT3/ITD-IN-2

    FLT3/ITD-IN-2 is a potent inhibitor of FLT3-ITD and is able to act on FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM) and FLT3-ITD (IC50: 1.0 nM).FLT3/ITD-IN-2 effectively inhibits the phosphorylation of FLT3 and is able to effectively inhibit the proliferation of acute myeloid leukemia cells.

    价 格：￥电议型 号：T63274产 地：中国大陆

  • T63174FLT3-IN-17；化合物 FLT3-IN-17FLT3-IN-17

    FLT3-IN-17 is an FAK inhibitor (IC50: 12 nM). FLT3-IN-17 inhibits the activity of CYPs and FLT3 mutants and has an IC50 of <0.5 nM for D835Y. FLT3-IN-17 can be used in cancer research.

    价 格：￥电议型 号：T63174产 地：中国大陆

  • T63135FLT3/CDK4-IN-1；化合物 FLT3/CDK4-IN-1FLT3/CDK4-IN-1

    FLT3/CDK4-IN-1 is a highly selective, potent, orally active dual inhibitor of FLT3/CDK4, acting on FLT3 (IC50: 7 nM) and CDK4 (IC50: 11 nM).FLT3/CDK4-IN-1 has good anti-tumour effects in vivo, showing anti-proliferative effects on some cancer cells.

    价 格：￥电议型 号：T63135产 地：中国大陆

  • T63127PDGFRα/FLT3-ITD-IN-3；化合物 PDGFRα/FLT3-ITD-IN-3PDGFRα/FLT3-ITD-IN-3

    PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα (IC50: 0.153 μM), FLT3 (IC50: 0.004 μM) and PDGFRα/FLT3-ITD-IN-3 has the potential to be studied in acute myeloid leukaemia or chronic eosinophilic leukaemia. .

    价 格：￥电议型 号：T63127产 地：中国大陆

  • T63058FLT3-IN-14；化合物 FLT3-IN-14FLT3-IN-14

    FLT3-IN-14 is a potent inhibitor of FLT3, acting on FLT3-WT (IC50: 5.6 nM) and FLT3-ITD (IC50: 1.4 nM). FLT3-IN-14 inhibits FLT3 (Y591) phosphorylation, arrests the cell cycle in G1 phase and induces apoptosis.

    价 格：￥电议型 号：T63058产 地：中国大陆

  • T62863FLT3/ITD-IN-4；化合物 FLT3/ITD-IN-4FLT3/ITD-IN-4

    FLT3/ITD-IN-4 (Compound 16) is a selective inhibitor of FLT3 internal tandem repeat mutations (FLT3-ITD) (IC50: 2.3 nM). FLT3/ITD-IN-4 can be used to study acute myeloid leukaemia.

    价 格：￥电议型 号：T62863产 地：中国大陆

  • T62824FLT3/ITD-IN-3；化合物 FLT3/ITD-IN-3FLT3/ITD-IN-3

    FLT3/ITD-IN-3 (Compound 19) is a potent inhibitor of FLT3-ITD, acting on FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM) and FLT3-ITD (IC50: 0.9 nM). FLT3/ITD-IN-3 showed potent inhibition of FLT3 phosphorylation and was effective against the proliferation of AML cells.

    价 格：￥电议型 号：T62824产 地：中国大陆

  • T62801FLT3/TrKA-IN-1；化合物 FLT3/TrKA-IN-1FLT3/TrKA-IN-1

    FLT3/TrKA-IN-1 is a potent FLT3/TrKA dual kinase inhibitor, capable of acting on FLT3 (IC50: 43.8 nM), FLT3-ITD (IC50: 97.2 nM), FLT3-TKD (IC50: 92.5 nM) and TrKA (IC50: 23.6 nM). -FLT3/TrKA-IN-1 has potential for acute myeloid leukaemia (AML) studies.

    价 格：￥电议型 号：T62801产 地：中国大陆

  • T62607FLT3-IN-15；化合物 FLT3-IN-15FLT3-IN-15

    FLT3-IN-15 is an orally active and potent FLT3 inhibitor, capable of acting on FLT3 (IC50: 0.87 nM) and FLT3/D835Y (IC50: 0.32 nM).

    价 格：￥电议型 号：T62607产 地：中国大陆

  • T62412FLT3-IN-12；化合物 FLT3-IN-12FLT3-IN-12

    FLT3-IN-12 is a selective, potent, orally active FLT3 kinase inhibitor that acts on FLT3-WT (IC50: 1.48 nM) and FLT3-D835Y (IC50: 2.87 nM). FLT3-IN-12 is more selective than c-KIT (>1000-fold). FLT3-IN-12 showed significant anti-AML effects, with an IC50 value of 0.75 nM for MV4-11 cells.

    价 格：￥电议型 号：T62412产 地：中国大陆

  • T62260FLT3-IN-11；化合物 FLT3-IN-11FLT3-IN-11

    FLT3-IN-11 (compound 30) is an orally active, potent and selective inhibitor of FLT3 kinase, acting on wild-type FLT3 (IC50: 7.22 nM) and FLT3-D835Y (IC50: 4.95 nM). FLT3-IN-11 exhibited significant anti-AML effects with an IC50 value of 3.2 nM for MV4-11 cells.

    价 格：￥电议型 号：T62260产 地：中国大陆

  • T61977FLT3/D835Y-IN-1；化合物 FLT3/D835Y-IN-1FLT3/D835Y-IN-1

    FLT3/D835Y-IN-1 (compound 13a) is a orally active, and selective inhibitor of FLT3 and FLT3/D835Y, with IC50s of 0.26 nM and 0.18 nM, respectively. FLT3/D835Y-IN-1 has anticancer efficacy, and has research value in AML (acute myeloid leukemia).

    价 格：￥电议型 号：T61977产 地：中国大陆

  • T61415FLT3/ITD-IN-1；化合物 FLT3/ITD-IN-1FLT3/ITD-IN-1

    FLT3/ITD-IN-1 (Compound 1) is a highly potent inhibitor of FLT3 internal tandem duplications (FLT3-ITD). It exhibits remarkable inhibitory effects against FLT3 and FLT3-ITD, with impressive IC50 values of 38.2 nM and 144.1 nM, respectively. Moreover, FLT3/ITD-IN-1 shows exceptional antiproliferative activities against several acute myeloid leukemia cell lines [1].

    价 格：￥电议型 号：T61415产 地：中国大陆

  • T6138TCS 359化合物TCS 359FLT3 Inhibitor

    TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.

    价 格：￥电议型 号：T6138产 地：中国大陆

  • T61101FLT3-IN-13；化合物 FLT3-IN-13FLT3-IN-13

    FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic cells. It exhibits potent activity against these targets, with IC50 values of 2.26 μM for both. Moreover, FLT3-IN-13 induces cell cycle arrest at the G2/M phase and promotes apoptosis. Notably, it displays considerable anticytotoxic activity, specifically against leukemia [1].

    价 格：￥电议型 号：T61101产 地：中国大陆

  • T50072FLT3 kinase inhibitor 2HCl；FLT3 kinase inhibitor 盐酸盐FLT3 kinase inhibitor 2HCl

    3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds.

    价 格：￥电议型 号：T50072产 地：中国大陆

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