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T75938Z-VRPR-FMK TFA;化合物 Z-VRPR-FMK TFAZ-VRPR-FMK TFA
Z-VRPR-FMK (TFA), a selective and irreversible inhibitor of Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), is a tetrapeptide shown to provide protection against influenza A virus (IAV) infection [1].
价 格:¥电议型 号:T75938产 地:中国大陆
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T73096Z-LEVD-FMK;化合物 Z-LEVD-FMKZ-LEVD-FMK
Z-LEVD-FMK, a cell-permeable caspase-4 inhibitor, effectively blocks endoplasmic reticulum (ER) stress-induced apoptosis in cancer cells.
价 格:¥电议型 号:T73096产 地:中国大陆
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T73093Z-VRPR-FMK;化合物 Z-VRPR-FMKZ-VRPR-FMK
Z-VRPR-FMK, an irreversible inhibitor of the MALT1 protein, effectively suppresses the proliferation and invasion of diffuse large B-cell lymphoma. This is achieved through the inhibition of MALT1-induced NF-κB activation and MMP (matrix metalloproteinase) expression.
价 格:¥电议型 号:T73093产 地:中国大陆
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T72435Z-LE(OMe)TD(OMe)-FMK;化合物 Z-LE(OMe)TD(OMe)-FMKZ-LE(OMe)TD(OMe)-FMK
Z-LE(OMe)TD(OMe)-FMK is a selective inhibitor of caspase-8, effectively inhibiting cellular apoptosis.
价 格:¥电议型 号:T72435产 地:中国大陆
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T71586Z-VAE(OMe)-fmk;化合物 Z-VAE(OMe)-fmkZ-VAE(OMe)-fmk
Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin´s C-terminal tail, thereby occupying the P1´ (leaving group) site, a binding site perhaps used by the unknown C-terminal extension of ubiquitin in the actual in vivo substrate(s) of UCHL1.
价 格:¥电议型 号:T71586产 地:中国大陆
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T7020Z-VAD-FMK;化合物Z-VAD(OH)-FMKZ-VAD(OH)-FMK|||Caspase Inhibitor VI|||Z-VAD;Z-VAD(OH)-FMK|||Caspase Inhib
Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not inhibit UCHL1 activity, even at concentrations up to 440 μM.
价 格:¥电议型 号:T7020产 地:中国大陆
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T7019Z-IETD-FMK;化合物Z-IETD-FMKZ-IE(OMe)TD(OMe)-FMK|||Caspase-8 Inhibitor;Z-IE(OMe)TD(OMe)-FMK|||Caspase-8
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.
价 格:¥电议型 号:T7019产 地:中国大陆
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T6738Z-FA-FMK;化合物Z-FA-FMKZ-FA-FMK
Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.
价 格:¥电议型 号:T6738产 地:中国大陆
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T6013Z-VAD(OMe)-FMK;化合物Z-VAD(OMe)-FMKZ-VAD-FMK|||Z-Val-Ala-Asp(OMe)-FMK;Z-VAD-FMK|||Z-Val-Ala-Asp(OMe)-FM
Z-VAD(OMe)-FMK is a pan-caspase inhibitor with irreversible properties; Z-VAD(OMe)-FMK is also an inhibitor of ubiquitin C terminal hydrolase L1 (UCHL1), which is irreversibly modified by targeting the UCHL1 active site.
价 格:¥电议型 号:T6013产 地:中国大陆
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T6005Z-DEVD-FMK;化合物Z-DEVD-FMKCaspase-3 Inhibitor;Caspase-3 Inhibitor
Z-DEVD-FMK (Caspase-3 Inhibitor) is a Caspase-3 inhibitor (IC50=18 μM) that is selective, irreversible, and cell-permeable. Z-DEVD-FMK inhibits apoptosis induced by caspase activation.
价 格:¥电议型 号:T6005产 地:中国大陆
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T41345AFMK;化合物AFMKFormyl-N-acetyl-5-methoxykynurenamine|||Acetyl-N-formyl-5-methoxykynurenamine;Formyl-N-a
AFMK (Formyl-N-acetyl-5-methoxykynurenamine) is an active metabolite of Melatonin with antioxidant and free radical scavenging activity. AFMK is a modulator of apoptosis and improves the anti-tumor effect of Gemcitabine in PANC-1 cells.
价 格:¥电议型 号:T41345产 地:中国大陆
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T40602Z-LEHD-FMK TFA;Z-LEHD-FMK TFAZ-LEHD-FMK TFA
Z-LEHD-FMK TFA is a specific and irreversible inhibitor of caspase-9, offering protection against detrimental reperfusion injury and moderating apoptosis. Additionally, Z-LEHD-FMK TFA demonstrates its neuroprotective potential in a rat model of spinal cord trauma.
价 格:¥电议型 号:T40602产 地:中国大陆
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T39344Z-VDVA-(DL-Asp)-FMK;Z-VDVA-(DL-Asp)-FMKZ-VDVA-(DL-Asp)-FMK
Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.
价 格:¥电议型 号:T39344产 地:中国大陆
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T38469(Rac)-Z-Phe-Phe-FMK;化合物(Rac)-Z-Phe-Phe-FMKCathepsin L-IN-2;Cathepsin L-IN-2
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .
价 格:¥电议型 号:T38469产 地:中国大陆
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T36331Z-AEVD-FMK;Z-AEVD-FMKZ-AEVD-FMK|||Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone;Z-AEVD-FMK|||Z-Ala-Glu-Val-A
Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.[2]
价 格:¥电议型 号:T36331产 地:中国大陆
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T23555Z-VEID-FMK;化合物 T23555Z-VEID-FMK
When compared to other caspase inhibitors, Z-DRHD-FMK inhibited caspase 6 activity more effectively than the general caspase inhibitor of Z-Val-Ala-Asp (OMe)-fluoromethy ketone (Z-VAD-FMK) or the caspase 6 inhibitor Z-Val-Glu(Ome)-Ile-Asp(OMe)-fluoromethyl ketone.However, it was less effective in inhibiting TNFα-induced apoptosis than Z-VAD-FMK or Z-VEID-FMK, presumably.
价 格:¥电议型 号:T23555产 地:中国大陆
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T21835Z-LEHD-fmk;多肽Z-LEHD-fmkZ-LEHD-fmk
Z-LEHD-FMK is a selective and potent caspase-9 inhibitor that protects against reperfusion injury and slows apoptosis.Z-LEHD-FMK exhibits antitumor and neuroprotective activity, increases the yield of in vitro-produced preimplantation embryos of Bubalus bubalis and alters the cellular stress response.
价 格:¥电议型 号:T21835产 地:中国大陆
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T15303FMK 9a;化合物FMK 9aFMK 9a
FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.
价 格:¥电议型 号:T15303产 地:中国大陆
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T11310FMK-MEA;化合物 T11310FMK-MEA
FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.
价 格:¥电议型 号:T11310产 地:中国大陆
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T10580BOC-D-FMK;3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯BOC-D-FMK
Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).
价 格:¥电议型 号:T10580产 地:中国大陆