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T9030SU4984inhibit,growth,Fibroblast growth factor receptor,Insulin Receptor,fibroblast,insulin,SU4984,SU
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
价 格：￥电议型 号：T9030产 地：中国大陆
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T6920ON123300Platelet-derived growth factor receptor,AMP-activated protein kinase,ON-123300,ON 123300,FGF
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
价 格：￥电议型 号：T6920产 地：中国大陆
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T9072TuxobertinibTuxobertinib,inhibit,ErbB-1,EGFR,BDTX 189,BDTX189,mutants,Epidermal growth factor recept
BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity.
价 格：￥电议型 号：T9072产 地：中国大陆
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TN1410Asperulosidic acidERK,Inhibitor,Nuclear factor-κB,Extracellular signal regulated kinases,NF-κB,Nucle
Asperulosidic acid has anti-tumor, anti-oxidant, and anti-inflammatory activities.ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways.
价 格：￥电议型 号：TN1410产 地：中国大陆
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TP1021Urocortin, humanCorticotropin-releasing Factor Receptor,Urocortin, human,Human urocortin1,inhibit,Hu
Urocortin (Ucn) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).
价 格：￥电议型 号：TP1021产 地：中国大陆
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TQ0059Ilorasertibanti-tumor,H1299,Platelet-derived growth factor receptor,Inhibitor,ABT 348,antiproliferat
Ilorasertib (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).
价 格：￥电议型 号：TQ0059产 地：中国大陆
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TQ0228DerazantinibARQ 087,Derazantinib,Fibroblast growth factor receptor,inhibit,FGFR,ARQ087,Inhibitor
Derazantinib (ARQ-087) is an ATP competitive tyrosine kinase inhibitor. It exhibits potent activity against FGFR1/FGFR2/FGFR3 chondrocytes (IC50s: 4.5 nM/1.8 nM/4.5 nM).
价 格：￥电议型 号：TQ0228产 地：中国大陆
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T91492BActpermeable,primary,inhibit,Eukaryotic Initiation Factor (eIF),2BAct,stress,defects,response,fibr
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response
价 格：￥电议型 号：T9149产 地：中国大陆
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T8330BIO-013077-01inhibit,Alkylation,Transforming growth factor beta receptors,BIO 013077 01,autophosphor
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
价 格：￥电议型 号：T8330产 地：中国大陆
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TL0016SulforapheneInhibitor,Sulforaphene,ERK,NF-κB,Nuclear factor-κB,Nuclear factor-kappaB,Extracellular s
Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.
价 格：￥电议型 号：TL0016产 地：中国大陆
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T7101Tyrphostin AG30HER1,ErbB-1,Inhibitor,EGFR,Tyrphostin AG30,Epidermal growth factor receptor,Tyrphosti
Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.
价 格：￥电议型 号：T7101产 地：中国大陆
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T6836FIIN-2inhibit,FGFR,FIIN2,FIIN 2,Fibroblast growth factor receptor,Inhibitor,FIIN-2
FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.
价 格：￥电议型 号：T6836产 地：中国大陆
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T6561Laquinimodinhibit,multiple sclerosis,relapsing remitting,carboxamide,Nuclear factor-kappaB,Apoptosis
Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
价 格：￥电议型 号：T6561产 地：中国大陆
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T6S0840EngeletinNuclear factor-kappaB,Engeletin,inhibit,NF-κB,Inhibitor,Nuclear factor-κB
1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
价 格：￥电议型 号：T6S0840产 地：中国大陆
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T6S1597Mulberroside AMulberroside A,Tumor Necrosis Factor Receptor,inhibit,TNF Receptor,Tyrosinase,TNFR,Inh
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of melanogenesis. 3. Mulberroside A has anti-inflammatory antiapoptotic effects. by decreasing the expressions of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6 and inhibiting the activation of NALP3, caspase-1, and nuclear factor-κB and the phosphorylation of extra
价 格：￥电议型 号：T6S1597产 地：中国大陆
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T6S0119DauricineNuclear factor-κB,Inhibitor,inhibit,Dauricine,Nuclear factor-kappaB,Apoptosis,NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profil
价 格：￥电议型 号：T6S0119产 地：中国大陆
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T6S1371Isovitexininhibit,Isovitexin,Nuclear factor-kappaB,Inhibitor,Nuclear factor-κB,NF-κB,JNK
1. Isovitexin exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.
价 格：￥电议型 号：T6S1371产 地：中国大陆
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T6S0781PhellodendrineNuclear factor-kappaB,inhibit,Akt,Nuclear factor-κB,Inhibitor,PKB,Protein kinase B,NF-
1. Phellodendrine has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.
价 格：￥电议型 号：T6S0781产 地：中国大陆
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T9921InfliximabTNFR1,Infliximab,anti-inflammatory,Avakine,Tumor Necrosis Factor Receptor,autoimmune,diabe
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn´s disease and rheumatoid arthritis.
价 格：￥电议型 号：T9921产 地：中国大陆
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T9010IMM-H007JNK,Nuclear factor-κB,WS 070117,IMM H007,AP-1,inflammatory,WS070117,inhibit,AMPK,atheroscler
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
价 格：￥电议型 号：T9010产 地：中国大陆
