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  • T63531HDAC6/HSP90-IN-1；化合物 HDAC6/HSP90-IN-1HDAC6/HSP90-IN-1

    HDAC6/HSP90-IN-1 is a potent and selective dual inhibitor of HDAC6 (IC50: 4.3 nM) and HSP90 (IC50: 46.8 nM).HDAC6/HSP90-IN-1 downregulates PD-L1 expression in INF-γ-treated H1975 lung cancer cells.HDAC6/HSP90-IN-1 exhibits tumor growth inhibition in H1975 xenograft mice.HDAC6/HSP90-IN-1 is a potent and selective dual inhibitor of HDAC6 (IC50: 4.3 nM) and HSP90 (IC50: 46.8 nM). 1 exhibited tumor growth inhibition in H1975 xenograft mice.

    价 格：￥电议型 号：T63531产 地：中国大陆

  • T63472HDAC6-IN-4；化合物 HDAC6-IN-4HDAC6-IN-4

    HDAC6-IN-4 (C10) is an orally active, highly selective, potent and non-significantly toxic HDAC6 inhibitor (IC50: 23 nM). HDAC6-IN-4 induces apoptosis and exhibits potent anti-tumor effects.

    价 格：￥电议型 号：T63472产 地：中国大陆

  • T6327Tubacin；HDAC6 抑制剂Tubacin

    Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.

    价 格：￥电议型 号：T6327产 地：中国大陆

  • T63247HDAC6-IN-12；化合物 HDAC6-IN-12HDAC6-IN-12

    HDAC6-IN-12 is a potent inhibitor of HDAC6 that binds in the DNA chain, causing DNA damage and exhibiting anticancer effects that can be used in cancer research.

    价 格：￥电议型 号：T63247产 地：中国大陆

  • T62046HDAC6-IN-5；化合物 HDAC6-IN-5HDAC6-IN-5

    HDAC6-IN-5 (compound 11b) is a potent and BBB-penetrated inhibitor of HDAC6 (IC50= 0.025 μM). HDAC6-IN-5 inhibits Aβ 1-42 self-aggregation and AChE, with IC 50s of 3.0 and 0.72 μM. HDAC6-IN-5 can enhance neurite outgrowth without significant neurotoxicity.

    价 格：￥电议型 号：T62046产 地：中国大陆

  • T61888mTOR/HDAC6-IN-1；化合物 mTOR/HDAC6-IN-1mTOR/HDAC6-IN-1

    mTOR/HDAC6-IN-1 is an effective dual inhibitor of histone deacetylase (HDAC6) and mammalian rapamycin (mTOR). The IC50 values for HDAC6 and mTOR are 56 nM and 133.7 nM respectively. MTOR/HDAC6-IN-1 can significantly induce autophagy and apoptosis and inhibit migration. MTOR/HDAC6-IN-1 has potential in the study of triple negative breast cancer (TNBC).

    价 格：￥电议型 号：T61888产 地：中国大陆

  • T61792HDAC6-IN-10；化合物 HDAC6-IN-10HDAC6-IN-10

    HDAC6-IN-10 is a potent and specific HDAC6 inhibitor, exhibiting an IC50 value of 0.73 nM. It demonstrates remarkable selectivity towards HDAC6, with a selectivity range of 144 to 10,941-fold over other HDAC isoforms. Furthermore, HDAC6-IN-10 exhibits notable anti-proliferative effects on multiple myeloma cells [1].

    价 格：￥电议型 号：T61792产 地：中国大陆

  • T61727HDAC6/8/BRPF1-IN-1；化合物 HDAC6/8/BRPF1-IN-1HDAC6/8/BRPF1-IN-1

    HDAC6/8/BRPF1-IN-1 is a dual inhibitor that targets HDAC6, HDAC8, and the bromodomain and PHD finger containing protein 1 (BRPF1). It exhibits inhibitory activity against HDAC1, HDAC6, and HDAC8 with IC50 values of 797 nM, 344 nM, and 908 nM, respectively. In addition, it inhibits BRPF1 with a Kd value of 175.2 nM. This compound is utilized in cancer research [1].

    价 格：￥电议型 号：T61727产 地：中国大陆

  • T61474HDAC6-IN-13；化合物 HDAC6-IN-13HDAC6-IN-13

    HDAC6-IN-13 (Compound 35m) is a potent and highly selective orally active inhibitor of HDAC6, with an IC50 of 0.019 μM. It also demonstrates inhibitory activity against HDAC1, HDAC2, and HDAC3, with IC50 values of 1.53 μM, 2.06 μM, and 1.03 μM, respectively. HDAC6-IN-13 exhibits substantial blood-brain barrier permeability and displays anti-inflammatory properties [1].

    价 格：￥电议型 号：T61474产 地：中国大陆

  • T61315HDAC6/HSP90-IN-2；化合物 HDAC6/HSP90-IN-2HDAC6/HSP90-IN-2

    HDAC6/HSP90-IN-2 (compound 6e) is a dual inhibitor targeting HDAC6 and Hsp90, exhibiting IC50 values of 105.7 nM and 61 nM, respectively. It is primarily utilized in cancer research [1].

    价 格：￥电议型 号：T61315产 地：中国大陆

  • T61139HDAC6-IN-3；化合物 HDAC6-IN-3HDAC6-IN-3

    HDAC6-IN-3 (Compound 14) is a potent anti-prostate cancer agent that acts as an orally active inhibitor of HDAC6. It has IC50 values ranging from 0.02-1.54 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10. Additionally, HDAC6-IN-3 also demonstrates effective inhibition of MAO-A (IC50 = 0.79 μM) and LSD1 [1].

    价 格：￥电议型 号：T61139产 地：中国大陆

  • T61044HDAC6-IN-11；化合物 HDAC6-IN-11HDAC6-IN-11

    HDAC6-IN-11 (Compound 9) has anti-proliferative activities against cancer cells. HDAC6-IN-11 is a selective inhibitor of HDAC6 with the IC50 value of 20.7 nM. The selectivity of HDAC6-IN-11 is more than 300-fold over HDAC other isoforms [1].

    价 格：￥电议型 号：T61044产 地：中国大陆

  • T60954HDAC6-IN-6；化合物 HDAC6-IN-6HDAC6-IN-6

    HDAC6-IN-6 (compound 6a) is a potent inhibitor of HDAC6 that can penetrate BBB with an IC50 value of 0.025 μM. HDAC6-IN-6 has potent inhibitory activity against AChE and Aβ 1-42 self-aggregation with IC50 values of 0.72 and 3.0 μM. HDAC6-IN-6 can enhance the outgrowth of neurite without significant neurotoxicity [1].

    价 格：￥电议型 号：T60954产 地：中国大陆

  • T60856HDAC6-IN-9；化合物 HDAC6-IN-9HDAC6-IN-9

    HDAC6-IN-9 (compound 12c) is a potent and selective inhibitor of HDAC6 with anti-proliferative activities. The IC 50 values of HDAC6-IN-9 for HDAC6, HDAC1,HDAC3, HDAC8, and HDAC10 is 4.2, 11.8, 15.2, 139.6, and 21.3 nM, respectively [1].

    价 格：￥电议型 号：T60856产 地：中国大陆

  • T36625LSD1/HDAC6-IN-1；LSD1/HDAC6-IN-1LSD1/HDAC6-IN-1；LSD1/HDAC6-IN-1

    LSD1/HDAC6-IN-1 is an orally active compound that functions as a dual inhibitor, targeting lysine specific demethylase 1 (LSD1) and histone deacetylase 6 (HDAC6). This compound demonstrates promising anti-tumor activity and is particularly valuable for research focused on multiple myeloma (MM) [1].

    价 格：￥电议型 号：T36625产 地：中国大陆

  • T22159TCS HDAC6 20b；化合物 T22159TCS HDAC6 20b

    TCS HDAC6 20b is a HDAC6 -selective inhibitor that blocks the growth of estrogen receptor α-positive breast cancer MCF-7 cells [1].

    价 格：￥电议型 号：T22159产 地：中国大陆

  • T1983CAY10603；化合物CAY10603HDAC6 Inhibitor|||BML-281；HDAC6 Inhibitor|||BML-281

    CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6.

    价 格：￥电议型 号：T1983产 地：中国大陆

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