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T0455Clozapine氯氮平;LX 100-129;HF 1854
Clozapine is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to
价 格:¥电议型 号:T0455产 地:中国大陆
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T0455ClozapineClozapine,HF 1854,LX 100-129
Clozapine is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to
价 格:¥电议型 号:T0455产 地:美洲
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T11138LLHF-535LHF-535
LHF-535 is an antiviral compound. It has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively.
价 格:¥电议型 号:T11138L产 地:美洲
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T135165-Methyltetrahydrofolic acid5-Methyltetrahydrofolic acid,5-Methyl THF,
5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivate of tetrahydrofolate. It is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.
价 格:¥电议型 号:T13516产 地:美洲
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T15479HFI-142HFI-142
HFI-142 is an inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 2.01 μM).
价 格:¥电议型 号:T15479产 地:美洲
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T15826LometrexolLometrexol,DDATHF,
Lometrexol has anticancer activity. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol is an antipurine antifolate, can inhibit the activity of glycinamide ribonuc
价 格:¥电议型 号:T15826产 地:美洲
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T19324Fmoc-N-Me-Ile-OHFmoc-N-Me-Ile-OH
Fmoc-N-Me-Ile-OH is a used in peptide synthesis.?
价 格:¥电议型 号:T19324产 地:美洲
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T19325Fmoc-N-Me-Val-OHFmoc-N-Me-Val-OH
Fmoc-N-Me-Val-OH is a modified peptide.
价 格:¥电议型 号:T19325产 地:美洲
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T2262CHF5074CHF5074,CSP-1103,Itanapraced
CHF5074, a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).
价 格:¥电议型 号:T2262产 地:美洲
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T5916Fmoc-N-Me-Phe-OHFmoc-N-Me-Phe-OH,Fmoc-N-methyl-L-phenylalanine,
Fmoc-N-Me-Phe-OH is a peptide inhibitor of Malaria Parasite
价 格:¥电议型 号:T5916产 地:美洲
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T82571DHFR-IN-10;化合物 DHFR-IN-10DHFR-IN-10
DHFR-IN-10 (compound 4c) is a potent inhibitor of dihydrofolate reductase (DHFR), displaying an inhibition concentration half-maximum (IC50) of 4.21 μM against Mycobacterium tuberculosis DHFR enzyme and demonstrates strong antituberculosis efficacy [1].
价 格:¥电议型 号:T82571产 地:中国大陆
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T82570DHFR-IN-11;化合物 DHFR-IN-11DHFR-IN-11
DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M. tuberculosis DHFR enzyme, reflected in an IC50 value of 5.70 μM [1].
价 格:¥电议型 号:T82570产 地:中国大陆
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T82493EGFR/HER2/DHFR-IN-2;化合物 EGFR/HER2/DHFR-IN-2EGFR/HER2/DHFR-IN-2
EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively. It exhibits anticancer activity, displaying IC50 values of 9.14, 7.33, 14.18, 24.87, 20.07, and 6.16 μM in Hep G2, HeLa, HEp-2, HCT 116, PC-3, and MCF7 cancer cell lines, respectively. Additionally, EGFR/HER2/DHFR-IN-2 has been shown to reduce the growth of breast cancer tumors [1].
价 格:¥电议型 号:T82493产 地:中国大陆
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T82492EGFR/HER2/DHFR-IN-3;化合物 EGFR/HER2/DHFR-IN-3EGFR/HER2/DHFR-IN-3
EGFR/HER2/DHFR-IN-3 (compound 4c) serves as an efficacious dual inhibitor specifically targeting EGFR/HER2, exhibiting IC50 values of 0.138 μM for EGFR and 0.092 μM for HER2, respectively. Moreover, it demonstrates inhibition of DHFR with an IC50 of 0.193 μM. Notably, this compound induces cell cycle arrest in the S phase and triggers apoptosis in MCF7 breast cancer cells [1].
价 格:¥电议型 号:T82492产 地:中国大陆
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T82383Fmoc-Lys(5-FITC)-OH;化合物 Fmoc-Lys(5-FITC)-OHFmoc-Lys(5-FITC)-OH
Fmoc-Lys(5-FITC)-OH serves as a fluorescent marker for polypeptides and proteins, utilizing FITC—a pH and Cu^2+-sensitive dye—as its fluorescence probe for amine labeling [1] [2] [3].
价 格:¥电议型 号:T82383产 地:中国大陆
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T82381Fmoc-Thr(GalNAc(Ac)3-β-D)-OH;化合物 Fmoc-Thr(GalNAc(Ac)3-β-D)-OHFmoc-Thr(GalNAc(Ac)3-β-D)-OH
Fmoc-Thr(GalNAc(Ac)3-β-D)-OH impedes the proliferation of cancer cells by selectively interacting with complex oncogenic pathways and enhancing the immune response [1].
价 格:¥电议型 号:T82381产 地:中国大陆
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T81381PROTAC eDHFR Degrader-1;化合物 PROTAC eDHFR Degrader-1PROTAC eDHFR Degrader-1
PROTAC eDHFR Degrader-1 is a potent degrader targeting eDHFR-YFP and various proteins of interest (POIs), such as YFP and Luciferase [1].
价 格:¥电议型 号:T81381产 地:中国大陆
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T79735DHFR-IN-9;化合物 DHFR-IN-9DHFR-IN-9
DHFR-IN-9 (compound 8A), a dihydrofolate reductase (DHFR) inhibitor, impedes purine and thymidylate biosynthesis, pivotal in cell proliferation and growth. It demonstrates potency against methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 with an IC50 of 0.25 μg/mL and exhibits anti-infective properties in mouse systemic and thigh infection models at doses of 2.5 mg/kg and 5 mg/kg administered intraperitoneally (ip). Furthermore, DHFR-IN-9 shows greater anticancer efficacy in a mouse
价 格:¥电议型 号:T79735产 地:中国大陆
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T79734DHFR-IN-8;化合物 DHFR-IN-8DHFR-IN-8
DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth. This compound effectively suppresses methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 with an IC50 of 15.6 ng/mL in mouse models of systemic and thigh infections [1].
价 格:¥电议型 号:T79734产 地:中国大陆
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T77904Fomc-Gly-Gly-Phe-Gly-OH;化合物 Fomc-Gly-Gly-Phe-Gly-OHFomc-Gly-Gly-Phe-Gly-OH
Compound D5 (Fomc-Gly-Gly-Phe-Gly-OH) serves as a synthetic intermediate in the construction of an ADC dual-drug-linker, and it is a crucial component for the assembly of this ADC dual-drug linking unit [1].
价 格:¥电议型 号:T77904产 地:中国大陆