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TN4660NiranthinNiranthin,inhibit,anti-leishmanial agent,leishmaniasis,Topoisomerase,Parasite,drug-resistan
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. Niranthin also exhibits anti-hepatitis B virus, antiinflammatory and antiallodynic actions.
价 格:¥电议型 号:TN4660产 地:中国大陆
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T0794Mepenzolate BromideHCAR2,PUMA-G,inhibit,Muscarinic acetylcholine receptor,Inhibitor,hM3R,gastrointes
Mepenzolate Bromide is a muscarinic antagonist used to treat gastrointestinal conditions.
价 格:¥电议型 号:T0794产 地:中国大陆
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T8426EncequidarMDR1,P-gp,Cluster of differentiation 243,inhibit,HM 30181,Encequidar,P-glycoprotein,Multid
Encequidar is a potent and selective P-glycoprotein inhibitor.
价 格:¥电议型 号:T8426产 地:中国大陆
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T17232VidupiprantProstaglandin Receptor,AMG-853,Inhibitor,orally,acid,cAMP,phenylacetic,asthma,PGD2,AMG 00
Vidupiprant is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in studies about the treatment of asthma.
价 格:¥电议型 号:T17232产 地:中国大陆
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T8548MetoprineInhibitor,histamine,HMT,Antifolate,barrier,Metoprine,Histone Methyltransferase,antitumor,N-
Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.
价 格:¥电议型 号:T8548产 地:中国大陆
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T8239Cromoglicic acidallergic rhinitis,Cromolyn,bronchial asthma,Cromoglicic acid,cell stabilizer,inhibit
Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.
价 格:¥电议型 号:T8239产 地:中国大陆
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T67747CB2R/FAAH modulator-3CB2R/FAAHmodulator3
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 has research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格:¥电议型 号:T67747产 地:中国大陆
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T41291MS-PPOHMS PPOH,MSPPOH
MS-PPOH is a potent and selective inhibitor of cytochrome P450 (CYP) epoxygenase. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 ?M, respectively
价 格:¥电议型 号:T41291产 地:中国大陆
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T10800CHMFL-ABL-121CHMFLABL121,CHMFL ABL 121
CHMFL-ABL-121 is a highly potent inhibitor of type II ABL kinase (IC50s: 2 nM and 0.2 nM against purified inactive ABL wt and T315I kinase protein).
价 格:¥电议型 号:T10800产 地:中国大陆
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T9018JHU37160Inhibitor,hM4Di,Clozapine,hM3Dq,DREADD,inhibit,Muscarinic acetylcholine receptor,JHU-37160,J
JHU 37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
价 格:¥电议型 号:T9018产 地:中国大陆
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T10799CHMFL-ABL-039CHMFLABL039,CHMFL ABL 039
CHMFL-ABL-039 is a type II native ABL kinase and drug-resistant V299L mutant BCR-ABL inhibitor (IC50s: 7.9 nM and 27.9 nM) used in the research of chronic myeloid leukemia.
价 格:¥电议型 号:T10799产 地:中国大陆
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T7811Pilsicainide HClatrial tachyarrhythmias,SUN-1165,Pilsicainide HCl,antiarrhythmic,inhibit,orally acti
Pilsicainide HCl is a pure sodium channel blocker
价 格:¥电议型 号:T7811产 地:中国大陆
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TQ0250CWHM-12CWHM 12,Inhibitor,Integrin,CWHM-12,CWHM12,inhibit
CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).
价 格:¥电议型 号:TQ0250产 地:中国大陆
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T7198E-4031Inhibitor,anti-arrhythmic,Potassium Channel,E4031,E 4031,KcsA,inhibit,E-4031,hERG
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)
价 格:¥电议型 号:T7198产 地:中国大陆
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T6547Ipratropium BromideIpratropium,asthma,chronic obstructive pulmonary disease,Ipratropium Bromide,inhi
Ipratropium is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema.
价 格:¥电议型 号:T6547产 地:中国大陆
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T6837FlavopiridolHMR1275,inhibit,L86-8275,CDK,Cyclin dependent kinase,Inhibitor,Autophagy,HMR 1275,Human
Flavopiridol (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1, 2, 4, 6 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1/2.
价 格:¥电议型 号:T6837产 地:中国大陆
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T10803CHMFL-KIT-033CHMFL KIT 033,CHMFLKIT033
CHMFL-KIT-033 is an effective and selective c-KIT inhibitor with an IC50 value of 45 nM for c-KIT T670I mutant in gastrointestinal stromal tumors.
价 格:¥电议型 号:T10803产 地:中国大陆
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T7322TheliatinibATP-competitive,inhibit,EGFR,ERK,cancer,esophageal,Epidermal growth factor receptor,HMPL-
Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR T790M/L858R mutant, respectively.
价 格:¥电议型 号:T7322产 地:中国大陆
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T8768MM-102 TFAMM102,HMTase Inhibitor IX,MM-102,MM 102 TFA,MM 102,inhibit,MM102 TFA,Histone Methyltransfe
MM-102 TFA is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM. MM-102 compound prevents the interaction between mixed lineage leukemia 1 (MLL1) and WD Trp-Asp repeat domain 5 (WDR5) and results in the inhibition of MLL1 H3K4 histone methyltransferase (HMT) activity. Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embry
价 格:¥电议型 号:T8768产 地:中国大陆
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T9926Omalizumabhumanized,asthma,IgE,CD40,allergic,IL-4,IL-6,FcγRIIb,Olizumab,Inhibitor,immunoglobulin,Fcε
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE)
价 格:¥电议型 号:T9926产 地:中国大陆