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T8161VicineInhibitor,Vicine,inhibit
Vicine, an alkaloid found in fava beans, is toxic in individuals and may cause haemolytic anaemia.
价 格:¥电议型 号:T8161产 地:中国大陆
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TN2108ProtohypericinProtohypericin,naphthodianthrone,Inhibitor,NSCLC,inhibit
Protohypericin is a naturally occurring naphthodianthrone derived from plant Hypericum perforatum.Radioiodinated protohypericin is used in Tumor necrosis targeted radiotherapy. Protohypericin exhibits photocytotoxicity.
价 格:¥电议型 号:TN2108产 地:中国大陆
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T6S1369Vitexinneurodegeneration,Vitexin,anti-cancer,anti-nociceptive,inhibit,Medicinal,anti-hypertensive,an
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can either inhibit or induce activities of CYP2C11 and CYP3A1. 5. Vitexin induces the novel p53-dependent metastatic and apoptotic pathway. 6. Vitexin protects brain against cerebral I/R injury, and this effect may be regulated by mitogen-activated protein kinase (MAPK) and apoptosis si
价 格:¥电议型 号:T6S1369产 地:中国大陆
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T8849PF-9601Nexcitotoxicity,neurodegenerative diseases,MAO,PF9601N,Monoamine Oxidase,MAO-B inhibitor,neur
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
价 格:¥电议型 号:T8849产 地:中国大陆
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T7846Aegelineαsyn,Aegeline,yeast,Inhibitor,protein,Sec22p,inhibit,toxicity,Fungal,SNARE
Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.
价 格:¥电议型 号:T7846产 地:中国大陆
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TN2347Methylsticinkava,Methylsticin,Inhibitor,inhibit,osteoclast
Methysticin is a kavalactone isolated from the kava roots. Methylsticin exhibit osteoclast formation inhibitory activity. It inhibits activation of NF-χB in lung adenocarcinoma tissue, activates Nrf2 in neurons and astroglia, decreases peak amplitude of voltage-gated Na+ channels in hippocampal neurons, and suppresses growth of Fusarium, Trichoderma, and Colletotrichum.
价 格:¥电议型 号:TN2347产 地:中国大陆
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T6566Levobupivacaine hydrochlorideCNS toxicity,gastric cancer,Na channels,Erastin,Inhibitor,analgesic,ana
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic.
价 格:¥电议型 号:T6566产 地:中国大陆
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T7779Nelfinavirproduction,Human immunodeficiency virus,protease,myeloma,inhibit,AG-1341,phosphorylation,c
Nelfinavir is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.
价 格:¥电议型 号:T7779产 地:中国大陆
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T7867FlutriafolDMI,fungicide,Inhibitor,Flutriafol,inhibit,dopamine,Fungal,triazole
Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonist
价 格:¥电议型 号:T7867产 地:中国大陆
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TQ0217Gomisin GHuman immunodeficiency virus,inhibit,HIV,Gomisin G,Inhibitor
Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9.
价 格:¥电议型 号:TQ0217产 地:中国大陆
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T9113MyristicinMyristicin,Serotonin Receptor,Inhibitor,5-hydroxytryptamine Receptor,5-HT Receptor,inhibit
Myristicin is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway. Myristicin may antagonize the anxiolytic effects of midazolam, increase anxiety, and affect motor movements. Myristicin can induce apoptosis as characterised by alterations i
价 格:¥电议型 号:T9113产 地:中国大陆
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T6386Ampicillin sodiumAmpicillin sodium,Antibiotic,inhibit,Inhibitor,Bacterial,Ampicillin
Ampicillin Sodium is the sodium salt form of ampicillin, a broad-spectrum semisynthetic derivative of aminopenicillin. Ampicillin sodium inhibits bacterial cell wall synthesis by binding to penicillin binding proteins, thereby inhibiting peptidoglycan synthesis, a critical component of the bacterial cell wall.
价 格:¥电议型 号:T6386产 地:中国大陆
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TN2283Tripterifordininhibit,HIV,Human immunodeficiency virus,replication,Tripterifordin,anti-HIV,Inhibitor
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.
价 格:¥电议型 号:TN2283产 地:中国大陆
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T8233BRD3308β-cells,glucolipotoxicity,inflammatory,BRD-3308,Human immunodeficiency virus,BRD3308,Histone
BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.
价 格:¥电议型 号:T8233产 地:中国大陆
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TN1853Lariciresinolinhibit,Inhibitor,Lariciresinol
Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel antifungal agent for the treatment of fungal infectious diseases in humans. Dietary lariciresinol can attenuate mammary tumor growth and reduce blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats.
价 格:¥电议型 号:TN1853产 地:中国大陆
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T41277PACMA 31bond,tumor,ovarian,athymic,PACMA31,inhibit,toxicity,colony,PACMA-31,mice,PACMA 31,oral,Inhib
PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.
价 格:¥电议型 号:T41277产 地:中国大陆
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T6S0119DauricineNuclear factor-κB,Inhibitor,inhibit,Dauricine,Nuclear factor-kappaB,Apoptosis,NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profil
价 格:¥电议型 号:T6S0119产 地:中国大陆
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T8238Fosamprenavir Calcium SaltHuman immunodeficiency virus,HIV,Fosamprenavir Calcium Salt,Inhibitor,inhi
Fosamprenavir Calcium Salt (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Fosamprenavir Calcium Salt has Anti-HIV infection.
价 格:¥电议型 号:T8238产 地:中国大陆
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TN7064CandicineCandicine
Candicine is a natural product from Stapelia gigantea.
价 格:¥电议型 号:TN7064产 地:中国大陆
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T6S0923HypericinHypericin,Dopamine β-monooxygenase,antitumor activity,Antibiotic,antiviral activity,telomer
1. Hypericin has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo.
价 格:¥电议型 号:T6S0923产 地:中国大陆