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T62950IRAK4-IN-18;化合物 IRAK4-IN-18IRAK4-IN-18
IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM). IRAK4-IN-18 inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats, a model of arthritis. IRAK4-IN-18 can be used to study arthritic diseases.
价 格:¥电议型 号:T62950产 地:中国大陆
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T62850IRAK4-IN-13;化合物 IRAK4-IN-13IRAK4-IN-13
IRAK4-IN-13 (compound 21) is a selective and potent IRAK4 inhibitor (IC50: 0.6 nM). iRAK4-IN-13 has a high metabolic clearance, with an intrinsic human liver microsomal (HLM) clearance of 96 μL/min/mg.
价 格:¥电议型 号:T62850产 地:中国大陆
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T61931IRAK4-IN-10;化合物 IRAK4-IN-10IRAK4-IN-10
IRAK4-IN-10 (compound 75) is an effective IRAK4 inhibitor (IC50 is 1.5 nM), which can block the MyD88-dependent signal pathway. IRAK4-IN-10 has research potential in inflammatory diseases, autoimmune diseases and cancer.
价 格:¥电议型 号:T61931产 地:中国大陆
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T61767IRAK4-IN-17;化合物 IRAK4-IN-17IRAK4-IN-17
IRAK4-IN-17 (Compound 5) is a highly potent inhibitor of IRAK4, exhibiting an impressive IC50 value of 1.3 nM [1]. This compound is particularly valuable for research focused on large B-cell lymphoma (DLBCL) [1].
价 格:¥电议型 号:T61767产 地:中国大陆
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T61734IRAK4-IN-9;化合物 IRAK4-IN-9IRAK4-IN-9
IRAK4-IN-9 (compound 73) is a highly potent inhibitor of IRAK4, displaying an impressive IC50 value of 1.5 nM. By blocking MyD88-dependent signaling, IRAK4-IN-9 exhibits promising potential for the investigation of inflammatory diseases, autoimmune diseases, and cancer [1].
价 格:¥电议型 号:T61734产 地:中国大陆
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T60899IRAK4-IN-11;化合物 IRAK4-IN-11IRAK4-IN-11
IRAK4-IN-11 (compound 6) is a potent inhibitor of IRAK4 with an IC 50 of 0.008 μM. IRAK4-IN-11 exhibits cell pIRAK4 potencies with an IC 50 of 0.19 μM [1].
价 格:¥电议型 号:T60899产 地:中国大陆
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T5354IRAK4-IN-7;化合物CA-4948CA-4948;CA-4948
IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.
价 格:¥电议型 号:T5354产 地:中国大陆
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T4140IRAK4-IN-1;化合物IRAK4-IN-1IRAK4-IN-1
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.
价 格:¥电议型 号:T4140产 地:中国大陆
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T39920PROTAC IRAK4 degrader-3;PROTAC IRAK4 degrader-3PROTAC IRAK4 degrader-3;PROTAC IRAK4 degrader-3
PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.
价 格:¥电议型 号:T39920产 地:中国大陆
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T39903PROTAC IRAK4 degrader-6;PROTAC IRAK4 degrader-6PROTAC IRAK4 degrader-6;PROTAC IRAK4 degrader-6
PROTAC IRAK4 degrader-6 is a potent Cereblon-based compound designed to degrade interleukin-1 receptor-associated kinase 4 (IRAK4).
价 格:¥电议型 号:T39903产 地:中国大陆
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T39902PROTAC IRAK4 degrader-5;PROTAC IRAK4 degrader-5PROTAC IRAK4 degrader-5;PROTAC IRAK4 degrader-5
PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.
价 格:¥电议型 号:T39902产 地:中国大陆
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T39901PROTAC IRAK4 degrader-4;PROTAC IRAK4 degrader-4PROTAC IRAK4 degrader-4;PROTAC IRAK4 degrader-4
PROTAC IRAK4 degrader-4 (US20190192668A1, compound I-127) is a Cereblon-based PROTAC specifically designed to target and degrade interleukin-1 receptor-associated kinase 4 (IRAK4).
价 格:¥电议型 号:T39901产 地:中国大陆
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T24174IRAK4-IN-16;化合物 T24174IRAK4-IN-16
IRAK4-IN-16 (compound 4) is a potent inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with an IC 50 of 2.5 nM. IRAK4-IN-16 exhibits cytotoxicity activity against OCI-LY10, TMD8, Ramos and HT cells, with IC 50 values of 0.2, 0.2, 0.6, and 2.7 μM, respectively [1].
价 格:¥电议型 号:T24174产 地:中国大陆
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T13843PROTAC IRAK4 ligand-1;化合物 T13843PROTAC IRAK4 ligand-1
PROTAC IRAK4 ligand-1 is a synthetic ligand for interleukin-1 receptor-associated kinase 4.
价 格:¥电议型 号:T13843产 地:中国大陆
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T13842PROTAC IRAK4 degrader-1;化合物 T13842PROTAC IRAK4 degrader-1
PROTAC IRAK4 degrader-1 is a degrader of PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4).
价 格:¥电议型 号:T13842产 地:中国大陆
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T11674IRAK4-IN-6;化合物 T11674IRAK4-IN-6
IRAK4-IN-6 is a selective and orally efficacious inhibitor of IRAK4, demonstrating an IC50 value of 4 nM. This compound specifically targets MyD88 L265P mutant diffuse large B-cell lymphoma [1].
价 格:¥电议型 号:T11674产 地:中国大陆
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T11673IRAK4-IN-4;化合物IRAK4-IN-4IRAK4-IN-4
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
价 格:¥电议型 号:T11673产 地:中国大陆