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T27650JAK3i;化合物JAK3iJAK-3i|||JAK 3i;JAK-3i|||JAK 3i
JAK3i is a selective covalent inhibitor of JAK3 kinase. JAK3i reveals two distinct temporal waves of STAT5 phosphorylation and more potently targets the second wave, which is required for cell cycle progression and T cell proliferation.
价 格:¥电议型 号:T27650产 地:中国大陆
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T2460JAK 3 inhibitor IV;化合物JAK 3 inhibitor IVZM 39923 hydrochloride|||Jak3 inhibitor IV;ZM 39923 hydrochl
JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
价 格:¥电议型 号:T2460产 地:中国大陆
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T2045JANEX-1;化合物WHI-P131Jak3 inhibitor I|||WHI-P131;Jak3 inhibitor I|||WHI-P131
JANEX-1 (Jak3 inhibitor I) is a cell-permeable, reversible, effective, ATP-competitive, and selective inhibitor of JAK3 (IC50: 78 μM); little inhibitory against JAK1/2, or Zap/Syk or SRC tyrosine kinases.
价 格:¥电议型 号:T2045产 地:中国大陆
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T1985WHI-P154;化合物WHI-P154Jak3 inhibitor ii;Jak3 inhibitor ii
WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.
价 格:¥电议型 号:T1985产 地:中国大陆
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T15607JAK3-IN-1;化合物 T15607JAK3-IN-1
JAK3-IN-1 is a selective and orally active JAK3 inhibitor (IC50: 4.8 nM). JAK3-IN-1 displays over 180-fold more selective for JAK3 than JAK1 (IC50: 896 nM) and JAK2 (IC50: 1050 nM).
价 格:¥电议型 号:T15607产 地:中国大陆
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T11709JAK3 covalent inhibitor-1;化合物 T11709JAK3 covalent inhibitor-1
JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus kinase 3 (JAK3), possessing an IC50 of 11 nM and demonstrating a 246-fold selectivity compared to other JAKs.
价 格:¥电议型 号:T11709产 地:中国大陆
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T10009JAK3-IN-7;JAK3抑制剂7JAK3-IN-7
JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction after organ transplantation, autoimmune disorders, allergic diseases, and chronic myeloproliferative disorders.
价 格:¥电议型 号:T10009产 地:中国大陆