您好，欢迎来到易推广！ 请登录 免费注册

上海陶术生物科技有限公司 主营产品：生物试剂,实验服务等

当前位置：易推广 > 上海陶术生物科技有限公司 > 产品展示

企业档案

会员类型：会员

已获得易推广信誉   等级评定
139成长值

(0 -40)基础信誉积累，可浏览访问

(41-90)良好信誉积累，可接洽商谈

(91+  )优质信誉积累，可持续信赖

易推广会员：5年

工商认证 【已认证】

最后认证时间：

注册号： 【已认证】

法人代表： 【已认证】

企业类型：生产商 【已认证】

注册资金：人民币万 【已认证】

产品数：86101

参观次数：3862734

手机网站：http://m.yituig.com/c135739/

旗舰版地址：http://tsbiochem.app17.com

自主品牌

自主品牌

已选条件

  • T79296JNK-IN-12；化合物 JNK-IN-12JNK-IN-12

    JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor with an IC50 value of 66.3 nM, comprising a mitochondrial-specific cell-penetrating peptide linked to SP600125, a selective JNK inhibitor. It selectively impedes mitochondrial JNK phosphorylation without inhibiting nuclear JNK signaling and has been shown to ameliorate Parkinson´s disease (PD) symptoms in both in vitro and in vivo studies [1].

    价 格：￥电议型 号：T79296产 地：中国大陆

  • T78829JNK2-IN-1；化合物 JNK2-IN-1JNK2-IN-1

    JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 ?M, exhibits anti-inflammatory effects by attenuating TNF-α and IL-6 secretion via inhibition of the NF-κB/MAPK pathway. It effectively mitigates symptoms associated with LPS-induced acute lung injury (ALI) and sepsis [1].

    价 格：￥电议型 号：T78829产 地：中国大陆

  • T7677JNK Inhibitor VIII；化合物JNK Inhibitor VIIITCS JNK 6o；TCS JNK 6o

    JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).

    价 格：￥电议型 号：T7677产 地：中国大陆

  • T74818JNK3 inhibitor-8；化合物 JNK3 inhibitor-8JNK3 inhibitor-8

    JNK3 Inhibitor-8 is a potent, selective, and orally active inhibitor that can cross the blood-brain barrier, targeting JNK3 with IC50 values of 21 nM for JNK3, 2203 nM for JNK2, and >10000 nM for JNK1. This compound demonstrates significant neuroprotective effects and holds promise for Alzheimer’s disease (AD) research [1].

    价 格：￥电议型 号：T74818产 地：中国大陆

  • T74817JNK3 inhibitor-7；化合物 JNK3 inhibitor-7JNK3 inhibitor-7

    JNK3 inhibitor-7, a potent and orally active compound that can cross the blood-brain barrier, acts as a JNK3 inhibitor with IC50 values of 53 nM for JNK3, 973 nM for JNK2, and 1039 nM for JNK1. Demonstrating significant neuroprotective effects, JNK3 inhibitor-7 holds potential for Alzheimer’s disease (AD) research [1].

    价 格：￥电议型 号：T74817产 地：中国大陆

  • T73109JNK-1-IN-1；化合物 JNK-1-IN-1JNK-1-IN-1

    JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM. It binds to MKK7cp, further reinforcing its role as a JNK-1 inhibitor.

    价 格：￥电议型 号：T73109产 地：中国大陆

  • T72715JNK3 inhibitor-4；化合物 JNK3 inhibitor-4JNK3 inhibitor-4

    JNK3 Inhibitor-4, a potent 2-aryl-1-pyrimidinyl-1H-imidazole-5-yl acetonitrile derivative, demonstrates a strong inhibitory effect on JNK3 with an IC 50 value of 1.0 nM. It exhibits exceptional selectivity against JNK3 when compared to other protein kinases, including isoforms JNK1 (IC 50 = 143.9 nM) and JNK2 (IC 50 = 298.2 nM). Additionally, JNK3 Inhibitor-4 benefits from neuroprotective properties and is predicted to permeate the blood-brain barrier effectively.

    价 格：￥电议型 号：T72715产 地：中国大陆

  • T72714JNK3 inhibitor-3；化合物 JNK3 inhibitor-3JNK3 inhibitor-3

    JNK3 Inhibitor-3 (compound 15g) is a selective, blood-brain barrier permeable, and orally active inhibitor of c-Jun N-terminal kinase 3 (JNK3) with IC50 values of 147.8 nM, 44.0 nM, and 4.1 nM against JNK1, JNK2, and JNK3, respectively. This compound has been shown to significantly enhance memory in mouse models of dementia and is utilized in Alzheimer’s disease research [1].

    价 格：￥电议型 号：T72714产 地：中国大陆

  • T62078Akt/NF-κB/JNK-IN-1；化合物 Akt/NF-κB/JNK-IN-1Akt/NF-κB/JNK-IN-1

    Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signalling pathways.Akt/NF-κB/JNK-IN-1 exhibits an inhibitory effect on nitric oxide production (IC50: 3.15 μM) and shows anti-inflammatory effects.

    价 格：￥电议型 号：T62078产 地：中国大陆

  • T61440TOPK-p38/JNK-IN-1；化合物 TOPK-p38/JNK-IN-1TOPK-p38/JNK-IN-1

    TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NO production. It demonstrates anti-inflammatory properties by inhibiting downstream phosphorylation of related proteins and preventing the degradation of TOPK [1].

    价 格：￥电议型 号：T61440产 地：中国大陆

  • T60805JNK3 inhibitor-2；化合物 JNK3 inhibitor-2JNK3 inhibitor-2

    JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor. The IC50 values of JNK3 inhibitor-2 for JNK1, JNK2, JNK3 are >100, >100, 0.25 μM, respectively. JNK3 inhibitor-2 also inhibits DDR1 and EGFR (T790M, L858R) [1].

    价 格：￥电议型 号：T60805产 地：中国大陆

  • T60534JNK-IN-11；JNK 抑制剂 11JNK-IN-11

    JNK-IN-11 is a potent JNK inhibitor that inhibits JNK1, JNK2, and JNK3 with IC50 values of 1.8, 21.4, and 2.2 ?M, respectively.JNK-IN-11 can be used to study abnormalities in immune function.

    价 格：￥电议型 号：T60534产 地：中国大陆

  • T40248JNK3 inhibitor-1JNK3 inhibitor-1JNK3 inhibitor-1

    JNK3 inhibitor-1 is a highly potent and selective compound that specifically inhibits JNK3 with an impressive IC50 value of 0.005 μM. In addition to its remarkable inhibitory effects, JNK3 inhibitor-1 possesses excellent oral bioavailability and the ability to efficiently penetrate the brain.

    价 格：￥电议型 号：T40248产 地：中国大陆

  • T38260SP 600125, negative control；SP 600125阴性对照JNK Inhibitor II, negative control；JNK Inhibitor II, negati

    SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125. SP 600125, negative control inhibits DTP3 and GADD45β/MKK7 (growth arrest and DNA damage-inducible β/mediator-activated protein kinase kinase kinase 7) and is capable of restoring activation.The IC50s of SP 600125, negative control against JNK2 and JNK3 were 18 and 24 μM, respectively.

    价 格：￥电议型 号：T38260产 地：中国大陆

  • T3598JNK-IN-7；化合物JNK-IN-7JNK inhibitor；JNK inhibitor

    JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM). It can also inhibit phosphorylation of c-Jun, which is a substrate of JNK kinase.

    价 格：￥电议型 号：T3598产 地：中国大陆

  • T3109SP600125；化合物Pyrazolanthrone1PMV|||JNK Inhibitor II|||Nsc75890|||Pyrazolanthrone；1PMV|||JNK Inhibitor

    SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.

    价 格：￥电议型 号：T3109产 地：中国大陆

  • T2668JNK-IN-8；化合物JNK-IN-8JNK Inhibitor XVI；JNK Inhibitor XVI

    JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.

    价 格：￥电议型 号：T2668产 地：中国大陆

  • T2234TCS JNK 5a；化合物SC202671SC202671|||SC 202671|||N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-na

    TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).

    价 格：￥电议型 号：T2234产 地：中国大陆

  • T10937LD-JNKI-1 acetate；化合物D-JNKI-1 acetateD-JNKI-1 acetate(1445179-97-4 Free base)|||AM-111 acetate；D-JNKI

    D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.

    价 格：￥电议型 号：T10937L产 地：中国大陆

  • T10937D-JNKI-1；化合物 T10937XG-102|||AM-111；XG-102|||AM-111

    D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor.

    价 格：￥电议型 号：T10937产 地：中国大陆

12共2页

展台首页| 公司简介| 供应产品| 产品目录| 公司动态| 荣誉证书| 招聘信息| 技术中心| 联系我们| 会员管理

易推广  设计制作，未经允许翻录必究.Copyright(C) 2009 http://www.yituig.com, All rights reserved.

以上信息由企业自行提供，信息内容的真实性、准确性和合法性由相关企业负责，易推广对此不承担任何责任.   总访问量：3862734

中国彩虹热线

快速导航

返回顶部
在线咨询

提交