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T82349GAGGVGKSA;化合物 GAGGVGKSAGAGGVGKSA
GAGGVGKSA, a wild-type KRAS G12D 9mer peptide, serves as an immunogenic neoantigen pivotal for cancer immunotherapy research [1].
价 格:¥电议型 号:T82349产 地:中国大陆
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T82348GAGGVGKSAL;化合物 GAGGVGKSALGAGGVGKSAL
GAGGVGKSAL, a wild-type KRAS G12D 10mer peptide, serves as an immunogenic neoantigen in cancer immunotherapy research [1].
价 格:¥电议型 号:T82348产 地:中国大陆
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T81466PI5P4Ks-IN-3;化合物 PI5P4Ks-IN-3PI5P4Ks-IN-3
PI5P4Ks-IN-3 (compound 30) is a covalent inhibitor of PI5P4K, exhibiting inhibition constants (IC50s) of 1.34 μM for PI5P4Kα and 9.9 μM for PI5P4Kβ. Notably, the compound demonstrates weak cellular activity [1].
价 格:¥电议型 号:T81466产 地:中国大陆
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T81157SIGSLAK;化合物 SIGSLAKSIGSLAK
SIGSLAK comprises the active site analogous to that of Escherichia coli (E. coli) penicillin-binding protein 1b (PBP 1b) [1].
价 格:¥电议型 号:T81157产 地:中国大陆
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T80196Garvicin KS, GakC;化合物 Garvicin KS, GakCGarvicin KS, GakC
Garvicin KS is a 32-amino-acid peptide that, in collaboration with two other peptides, GakA and GakB, constitutes the bacteriocin GarKS. This compound impairs fibroblast viability and proliferation and exhibits antimicrobial activity against MSSA, demonstrating minimum inhibitory concentration (MIC) values ranked as GakB > GakC > GakA [1].
价 格:¥电议型 号:T80196产 地:中国大陆
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T80195Garvicin KS, GakB;化合物 Garvicin KS, GakBGarvicin KS, GakB
Garvicin KS (GarKS) is a bacteriocin comprising a 34-amino-acid peptide, GakB, along with two additional peptides, GakA and GakC. GakB specifically impairs fibroblast viability and proliferation. When combined with GakA, GarKS demonstrates enhanced peptide stability, antimicrobial activity, and notable impacts on fibroblast viability and proliferation. Regarding methicillin-sensitive Staphylococcus aureus (MSSA) inhibition, minimum inhibitory concentration (MIC) values rank the peptides in desce
价 格:¥电议型 号:T80195产 地:中国大陆
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T80194Garvicin KS, GakA;化合物 Garvicin KS, GakAGarvicin KS, GakA
Garvicin KS (GarKS) is a bacteriocin composed of a 34 amino acid peptide, GakA, and two additional peptides, GakB and GakC. GakA alone has been found to reduce fibroblast viability and proliferation. When combined with GakB, GakA forms an effective duo that exhibits notable peptide stability, antimicrobial potency, and an influence on fibroblast viability and proliferation. Among the Garvicin KS peptides, GakB is the most effective against MSSA, with minimum inhibitory concentration (MIC) values
价 格:¥电议型 号:T80194产 地:中国大陆
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T79500LKSK94 FA;KSK94 甲酸盐KSK94 FA(2566716-07-0 Free base);KSK94 FA(2566716-07-0 Free base)
KSK94 FA is a potent histamine H3 receptor antagonist that inhibits H3 receptors and is used in the study of neuropathic pain and obesity.
价 格:¥电议型 号:T79500L产 地:中国大陆
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T79500KSK94;化合物 KSK94KSK94
KSK94 is a specific H3 receptor antagonist that inhibits H3, sigma-1, and sigma-2 receptors , with Ki values of 7.9, 2958, and 75.2 nM, respectively, and can be used to study injurious pain and neuropathic pain.
价 格:¥电议型 号:T79500产 地:中国大陆
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T79499KSK68;化合物KSK68KSK68
KSK68 is a potent dual sigma-1 and histamine H3 receptor antagonist with potential analgesic activity and high affinity for H3 receptors, sigma-1, sigma-2 receptors.KSK68 can be used in the study of pain related diseases.
价 格:¥电议型 号:T79499产 地:中国大陆
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T78762SIKs-IN-1;化合物 SIKs-IN-1SIKs-IN-1
SIKs-IN-1 (compound 8h), a pyrimidine-5-carboxamide derivative, functions as an inhibitor of Salt-inducible kinases (SIKs), which play a role in the M1/M2 macrophage polarization linked to inflammation. By inhibiting SIK activity, this compound increases the anti-inflammatory cytokine IL-10 and decreases the pro-inflammatory cytokine IL-12, demonstrating significant anti-inflammatory efficacy in a DSS-induced colitis model [1].
价 格:¥电议型 号:T78762产 地:中国大陆
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T77733TNKS-2-IN-2;TNKS-2 抑制剂 2TNKS-2-IN-2
TNKS-2-IN-2 is a novel and potent TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for the study of colon cancer lung cancer and breast cancer.
价 格:¥电议型 号:T77733产 地:中国大陆
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T77675TNKS-2-IN-1;TNKS抑制剂1TNKS-2-IN-1
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the release of IL-1β from the NLRP3 inflammasome (IC50: 5 μM) by inhibiting IL-1β release from ATP-stimulated J1A.774 cells.
价 格:¥电议型 号:T77675产 地:中国大陆
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T77593KSK67;化合物KSK67KSK67
KSK67 is a selective dual antagonist of sigma-2 and histamine H3 receptors with inhibitory effects on H3 receptors, sigma-1, and sigma-2 receptors, with Ki values of 3.2, 1531, and 101 nM, respectively.KSK67 can be used to study injury pain and neuropathic pain.
价 格:¥电议型 号:T77593产 地:中国大陆
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T76398FKKSFKL-NH2;化合物 FKKSFKL-NH2FKKSFKL-NH2
FKKSFKL-NH2 is a selective peptide for protein kinase C, employed in biochemical research [1].
价 格:¥电议型 号:T76398产 地:中国大陆
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T75345HKSOX-1m (5/6-mixture) (hydrobromide);化合物 HKSOX-1m (5/6-mixture) (hydrobromide)HKSOX-1m (5/6-mixture
HKSOX-1m hydrobromide (5/6-mixture), a mitochondria-targeted O2?? fluorescent probe (Ex/Em=509/534nm; green), demonstrates exceptional selectivity and sensitivity for O2?? across a wide pH spectrum, robustly distinguishing it from strong oxidants and prevalent cellular reductants [1].
价 格:¥电议型 号:T75345产 地:中国大陆
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T73937HKSOX-1r (5/6-mixture);化合物 HKSOX-1r (5/6-mixture)HKSOX-1r (5/6-mixture)
HKSOX-1r (5/6-mixture) serves as a fluorescent probe designed for the imaging and detection of endogenous superoxide in live cells and in vivo applications. It demonstrates superior selectivity and sensitivity to the superoxide anion radical [1]. For storage, it is essential to protect this compound from light.
价 格:¥电议型 号:T73937产 地:中国大陆
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T73936HKSOX-1 (5/6-mixture);化合物 HKSOX-1 (5/6-mixture)HKSOX-1 (5/6-mixture)
HKSOX-1, a fluorescent probe designed for the imaging and detection of endogenous superoxide in live cells and in vivo, demonstrates outstanding selectivity and sensitivity towards the superoxide anion radical [1]. For storage, it is important to protect HKSOX-1 from light.
价 格:¥电议型 号:T73936产 地:中国大陆
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T73206Wikstrol A;化合物 Wikstrol AWikstrol A
Wikstrol A, a potent antifungal, antimitotic, and anti-HIV-1 agent, demonstrates significant effects across various biological targets. It induces morphological deformation in P. oryzae mycelia, with a minimum morphological deformation concentration (MMDC) of 70.1 ?M and inhibits microtubule polymerization, evidenced by an IC50 value of 131 ?M. Additionally, Wikstrol A exhibits anti-HIV-1 activity with an IC50 value of 67.8 ?M.
价 格:¥电议型 号:T73206产 地:中国大陆
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T72922TNKS1/2-IN-1;化合物 TNKS1/2-IN-1TNKS1/2-IN-1
TNKS1/2-IN-1 is a potent inhibitor of tankyrase (TNKS1/2), exhibiting pIC50 values between 7.1-8.2. It is utilized in research targeting cancer, fibrosis, and other hyperproliferative diseases.
价 格:¥电议型 号:T72922产 地:中国大陆