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T82482ELDKWA;化合物 ELDKWAELDKWA
ELDKWA, a highly conserved sequence of amino acids located on the ecto-domain of gp41, serves as the epitope for mAb 2F5, a neutralizing monoclonal antibody against human immunodeficiency virus type 1 [1] [2].
价 格:¥电议型 号:T82482产 地:中国大陆
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T82326Genkwadaphnin;化合物 GenkwadaphninGenkwadaphnin
Genkwadaphnin, a daphnane diterpenoid, targets importin-β1, reducing the nuclear accumulation of CRPC drivers and suppressing downstream oncogenic signaling. Demonstrating potent anti-tumor effects, it inhibits castration-resistant prostate cancer (CRPC) in vivo in mice [1].
价 格:¥电议型 号:T82326产 地:中国大陆
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T78563[Leu13]-Motilin;化合物 [Leu13]-MotilinKW-5139;KW-5139
[Leu13]-Motilin (KW-5139) is an analogue of the gastrointestinal hormone motilin that induces concentration-dependent contractions in rabbit gastrointestinal tissues, including the gastric antrum, duodenum, jejunum, ileum, and descending colon in vitro [1].
价 格:¥电议型 号:T78563产 地:中国大陆
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T78276KWAR 23;化合物 KWAR 23KWAR 23
KWAR23, an anti-human SIRPα antibody, exhibits high-affinity binding to human SIRPα, inhibiting its interaction with CD47. Demonstrating antitumor activity, KWAR23 is efficacious in conjunction with tumor-opsonizing antibodies, making it a valuable agent for cancer immunotherapy research [1].
价 格:¥电议型 号:T78276产 地:中国大陆
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T76782Mogamulizumab;莫格利珠单抗KW-0761;KW-0761
Mogamulizumab (KW-0761) is a monoclonal antibody against T cell CC chemokine receptor 4. Mogamulizumab has anticancer activity, eliminating tumor cells through antibody dependent cytotoxicity (ADCC), and can be used to study cancer, adult T-cell leukemia/lymphoma (ATLL), cutaneous T-cell lymphoma (CTCL).
价 格:¥电议型 号:T76782产 地:中国大陆
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T74801KWCN-41;化合物 KWCN-41KWCN-41
KWCN-41, a selective and efficient RIPK1 kinase inhibitor, exhibits an IC50 value of 88 nM. It specifically targets cell necrosis without affecting apoptosis and possesses anti-inflammatory properties [1].
价 格:¥电议型 号:T74801产 地:中国大陆
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T70876KW-2450 Tosylate;化合物 KW-2450 TosylateKW-2450 Tosylate
KW-2450 Tosylate is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 Tosylate selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in t
价 格:¥电议型 号:T70876产 地:中国大陆
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T6S0095Genkwanin;芫花素7-O-Methylapigenin|||Puddumetin|||Apigenin 7-methyl ether;7-O-Methylapigenin|||Puddumet
1. Genkwanin (Apigenin 7-methyl ether) exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug resistance protein (MDR)-mediated efflux mechanisms.
价 格:¥电议型 号:T6S0095产 地:中国大陆
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T6881LLTX315 acetate;LTX315醋酸盐KKWWKKW-Dip-K-NH2 acetate|||Oncopore acetate|||Ruxotemitide acetate|||LTX315
LTX315 acetate (Oncopore acetate) is an oncolytic peptide with potent anticancer activity, with IC50 values of 34.3 ?M for MRC-5, 8.3 ?M for A20, and 11 ?M for AT84, respectively.
价 格:¥电议型 号:T6881L产 地:中国大陆
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T68405LKW-2450 Formate;KW-2450 甲酸盐KW-2450 Formate
KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.
价 格:¥电议型 号:T68405L产 地:中国大陆
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T68405KW-2450 free base;化合物 KW-2450 free baseKW-2450 free base
KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in
价 格:¥电议型 号:T68405产 地:中国大陆
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T6558KW-2478;化合物KW2478KW2478;KW2478
KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.
价 格:¥电议型 号:T6558产 地:中国大陆
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T6552Istradefylline;伊曲茶碱KW-6002;伊曲茶碱|||KW-6002
Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails. It has been used in trials studying the treatment and basic science of Drug Abuse, Sleep Disorder, Hepatic Impairment, Parkinson´s Disease, and Restless Legs Syndrome, among others.
价 格:¥电议型 号:T6552产 地:中国大陆
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T6227Benidipine hydrochloride;盐酸贝尼地平(±)-Benidipine|||Benidipine HCl|||KW-3049|||Coniel;(±)-Benidipine|||B
Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.
价 格:¥电议型 号:T6227产 地:中国大陆
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T4S0094Hydroxygenkwanin;羟基芫花素Luteolin 7-methylether|||7-O-Methylluteolin;羟基芫花素|||Luteolin 7-methylether|||7
1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin and Hydroxygenkwanin may be a promising method for glioma chemotherapy.
价 格:¥电议型 号:T4S0094产 地:中国大陆
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T37695NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ;NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNMNNAGDKWSAFLKE
NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ, an ACE2-related peptide, serves as a valuable research tool for comprehending ACE2 functions.
价 格:¥电议型 号:T37695产 地:中国大陆
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T36762KW-8232;KW-8232KW-8232
KW-8232, an orally active anti-osteoporotic agent, reduces the biosynthesis of PGE2[1].
价 格:¥电议型 号:T36762产 地:中国大陆
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T32429KW 2149;化合物 T32429KT6149|||KW2149|||KW-2149;KT6149|||KW2149|||KW-2149
KW 2149 is a compound derived from mitomycin C.
价 格:¥电议型 号:T32429产 地:中国大陆