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  • T36404LPRLX-93936 HCLPRLX93936 HCL,PRLX 93936 HCL

    PRLX-93936 hcl is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.

    价 格：￥电议型 号：T36404L产 地：中国大陆

  • T6949PLX7904PLX 7904,PB 04,Inhibitor,inhibit,PB-04,PLX-7904,Raf kinases,PLX7904,Raf

    PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.

    价 格：￥电议型 号：T6949产 地：中国大陆

  • T6273Vadimezan伐地美生；ASA-404；NSC 640488；5,6-Dimethylxanthenone-4-acetic Acid；DMXAA

    Vadimezan is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiog

    价 格：￥电议型 号：T6273产 地：中国大陆

  • T6044Telotristat Etiprate特罗司他马尿酸盐；LX1606 (Hippurate)；LX 1606 Hippurate

    Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.

    价 格：￥电议型 号：T6044产 地：中国大陆

  • T5600DarovasertibLXS196

    LXS196 is a potent, selective and orally active protein kinase C (PKC) inhibitor(IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively).

    价 格：￥电议型 号：T5600产 地：中国大陆

  • T4973Paraxanthine1,7-DIMETHYLXANTHINE；1,7-二甲基黄嘌呤

    Paraxanthine is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is structurally similar to caffeine and possibly mediates the phys

    价 格：￥电议型 号：T4973产 地：中国大陆

  • T4398LX2343

    LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.

    价 格：￥电议型 号：T4398产 地：中国大陆

  • T4067VLX1570

    VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.

    价 格：￥电议型 号：T4067产 地：中国大陆

  • T3579PLX8394

    PLX8394 is an orally active inhibitor of serine/threonine-protein kinase B-Raf (BRAF) protein. PLX8394 can selectively bind to and inhibit the activity of both wild-type and mutated forms of BRAF, then inhibit the proliferation of tumor cells which expres

    价 格：￥电议型 号：T3579产 地：中国大陆

  • T3547SotagliflozinLP-802034；LX-4211

    LX-4211 is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potential antihyperglycemic activity.

    价 格：￥电议型 号：T3547产 地：中国大陆

  • T35343MTI-31MTI-31；LXI-15029

    MTI-31 is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding assays. MTI-31 shows an IC50 of 39 nM for mTOR i

    价 格：￥电议型 号：T35343产 地：中国大陆

  • T27719KD-026KD026；SLx 4090；SLx-4090；KD 026；SLx4090

    KD-026, a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.

    价 格：￥电议型 号：T27719产 地：中国大陆

  • T27133DCLX069DCLX 069；DCLX-069

    DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 value of 17.9 ?M. DCLX069 occupies the SAM binding pocket to exert the inhibitory effect. DCLX069 effectively blocks cell proliferation in breast cancer, liver canc

    价 格：￥电议型 号：T27133产 地：中国大陆

  • T270768-Cyclopentyl-1,3-dimethylxanthineA1受体拮抗剂,CPT；CPT

    8-Cyclopentyl-1,3-dimethylxanthine?is a potent antagonist of adenosine A1 receptor.

    价 格：￥电议型 号：T27076产 地：中国大陆

  • T2473PLX-4720PLX4720

    PLX-4720 is a potent and selective inhibitor of B-Raf (V600E) (IC50: 13 nM), equally potent to c-Raf-1(Y340D and Y341D mutations).

    价 格：￥电议型 号：T2473产 地：中国大陆

  • T2382Vemurafenib维罗非尼；PLX4032；RO5185426；RG7204

    Vemurafenib (PLX4032) is a novel and potent B-Raf (V600E) inhibitor (IC50: 31 nM).

    价 格：￥电议型 号：T2382产 地：中国大陆

  • T22379LNLX-204 hydrochloride（2170405-10-2 free base）

    NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).

    价 格：￥电议型 号：T22379L产 地：中国大陆

  • T21389Enprofylline恩丙茶碱；3-propylxanthine；Enprofilina；Enprofyllinum；3-n-Propylxanthine；3-Propylxanthine

    Enprofylline, a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of sickle cell disease, diabetic neuropathy, and cerebro

    价 格：￥电议型 号：T21389产 地：中国大陆

  • T2115PexidartinibPLX-3397

    Pexidartinib is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.

    价 格：￥电议型 号：T2115产 地：中国大陆

  • T1783LXR-623WAY 252623；LXR623

    WAY-252623 (LXR-623) is an orally bioavailable and highly specifical synthetic modulator of LXR.

    价 格：￥电议型 号：T1783产 地：中国大陆

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