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T83686Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 acetate;化合物 Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 acetateMca-SEVNLDAEFR-K(Dnp)-R
Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 is a fluorogenic substrate designed for the quantification of β-secretase (BACE) activity. When cleaved by BACE, it liberates 7-methoxycoumarin-4-acetyl (Mca), a compound whose fluorescence, with excitation and emission peaks at 328 nm and 420 nm respectively, serves as a measurable indicator of BACE enzymatic action.
价 格:¥电议型 号:T83686产 地:中国大陆
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T83181Ac-IETD-AMC;化合物 Ac-IETD-AMCAc-IETD-AMC
Ac-IETD-AMC, a fluorogenic substrate specific for caspase-8 and granzyme B with an acetyl (Ac) moiety, is commonly utilized to quantify caspase-8 activity [1].
价 格:¥电议型 号:T83181产 地:中国大陆
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T82617D-Ala-Lys-AMCA TFA;化合物 D-Ala-Lys-AMCA TFAD-Ala-Lys-AMCA TFA
D-Ala-Lys-AMCA TFA is a proton-coupled oligopeptide transporter 1 (PEPT1) substrate characterized by its emission of blue fluorescence. It has been demonstrated through fluorescence analysis that this compound can be transported into liver cancer cells and Caco-2 cells. Its utility extends to the characterization of PEPT1-specific substrates or inhibitors [1] [2].
价 格:¥电议型 号:T82617产 地:中国大陆
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T81839MCA succinimidyl ester;化合物 MCA succinimidyl esterMCA succinimidyl ester
MCA succinimidyl ester, a derivative of MCA, selectively reacts with amines and serves as a peptide substrate for fluorescence resonance energy transfer (FRET) [1].
价 格:¥电议型 号:T81839产 地:中国大陆
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T81838Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human);化合物 Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 t
Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide utilized as a fluorescence resonance energy transfer (FRET) based substrate for proteolytic activity assays, wherein the cleavage-induced change in fluorescence intensity serves as the measure of enzymatic activity [1].
价 格:¥电议型 号:T81838产 地:中国大陆
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T81837MCaE12A;化合物 MCaE12AMCaE12A
MCaE12A, a potent modulator of RyR2, enhances the channel´s sensitivity to cytoplasmic calcium concentrations, facilitating its opening. This compound serves as a critical instrument for examining RyR2 structure-to-function relationships and for modulating Ca2+ homeostasis and dynamics in cardiac cells [1].
价 格:¥电议型 号:T81837产 地:中国大陆
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T81836Mca-SEVNLDAEFK(Dnp)-NH2;化合物 Mca-SEVNLDAEFK(Dnp)-NH2Mca-SEVNLDAEFK(Dnp)-NH2
Mca-SEVNLDAEFK(Dnp)-NH2 is a fluorogenic substrate featuring a 7-methoxycoumarin moiety whose fluorescence is quenched by the adjacent 2,4-dinitrophenyl group through resonance energy transfer. This compound serves as a probe for assessing peptidase activity; enzymatic cleavage of the amide bond separating the fluorophore and quencher results in increased fluorescence. It is particularly useful for quantifying the activity of BACE-1 [1].
价 格:¥电议型 号:T81836产 地:中国大陆
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T81030Tauro-β-muricholic acid;化合物 Tauro-β-muricholic acidTβMCA;TβMCA
Tauro-β-muricholic acid (TβMCA), a trihydroxylated bile acid, acts as a competitive and reversible FXR antagonist (IC 50 = 40 μM) and exhibits antiapoptotic effects by inhibiting bile acid-induced hepatocellular apoptosis and preserving mitochondrial membrane potential [1] [2].
价 格:¥电议型 号:T81030产 地:中国大陆
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T80211Ac-KQL-AMC;化合物 Ac-KQL-AMCAc-KQL-AMC
Ac-KQL-AMC is a fluorogenic substrate designed for the quantification of Trypsin-like activity, emitting detectable fluorescence upon proteasomal cleavage [1].
价 格:¥电议型 号:T80211产 地:中国大陆
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T80110Ac-VRPR-AMC;化合物 Ac-VRPR-AMCAc-VRPR-AMC
Ac-VRPR-AMC is a fluorogenic substrate for metacaspase activity assays, facilitating the detection and measurement of metacaspase activity [1].
价 格:¥电议型 号:T80110产 地:中国大陆
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T80048Mca-YVADAP-Lys(Dnp)-OH TFA;化合物 Mca-YVADAP-Lys(Dnp)-OH TFAMca-YVADAP-Lys(Dnp)-OH TFA
Mca-YVADAP-Lys(Dnp)-OH TFA serves as a fluorogenic substrate specifically utilized for caspase-1 and angiotensin-converting enzyme 2 (ACE2) [1].
价 格:¥电议型 号:T80048产 地:中国大陆
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T78436Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2;化合物 Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2Mca-Lys
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the real-time quantification of MMP enzymatic activity. As an extended variant of the MMP substrate (FS-1), it demonstrates increased specificity against collagenases (MMP-1, MMP-8, MMP-13) and MT1-MMP, evidenced by higher specificity constants (Ex/Em=325 nm/400 nm). [1]
价 格:¥电议型 号:T78436产 地:中国大陆
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T78435Mca-(ala7,lys(dnp)9)-bradykinin;化合物 Mca-(ala7,lys(dnp)9)-bradykininMca-(ala7,lys(dnp)9)-bradykinin
Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1). It features a (7-methoxycoumarin-4-yl)acetyl (Mca) group for fluorescence and a 2,4-dinitrophenyl (Dnp) group for quenching, yielding a significant increase in fluorescence when the substrate is cleaved [1].
价 格:¥电议型 号:T78435产 地:中国大陆
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T78434Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA;化合物 Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (
Mca-(endo-1α-Dap(Dnp))-TNF-α(-5 to +6) amide (human) TFA is a peptide that functions as a fluorescence resonance energy transfer (FRET)-based substrate, with its activity determined by the change in fluorescence intensity following cleavage [1].
价 格:¥电议型 号:T78434产 地:中国大陆
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T78426MCAAD-3;化合物 MCAAD-3MCAAD-3
MCAAD-3, a near-infrared Aβ imaging probe, exhibits blood-brain barrier permeability and strong affinity for Aβ polymers (Ki >106 nM). It successfully labels Aβ plaques in the brains of transgenic mice [1].
价 格:¥电议型 号:T78426产 地:中国大陆
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T78409LBoc-Val-Pro-Arg-MCA TFA;Boc-Val-Pro-Arg-MCA三氟乙酸盐Boc-Val-Pro-Arg-MCA TFA
Boc-Val-Pro-Arg-MCA TFA is a sensitive fluorescent substrate that is a thrombin substrate for the determination of trypsin-like serine protease activity.
价 格:¥电议型 号:T78409L产 地:中国大陆
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T78409Boc-Val-Pro-Arg-MCA hydrochloride;化合物 Boc-Val-Pro-Arg-MCA hydrochlorideBoc-Val-Pro-Arg-MCA HCl;Boc-V
Boc-Val-Pro-Arg-MCA hydrochloride (Boc-Val-Pro-Arg-MCA HCl) is a sensitive fluorescent substrate for the determination of trypsin-like serine proteases activity.
价 格:¥电议型 号:T78409产 地:中国大陆
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T76606Ac-Trp-Glu-His-Asp-AMC;化合物 Ac-Trp-Glu-His-Asp-AMCAc-Trp-Glu-His-Asp-AMC
Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1 [1] .
价 格:¥电议型 号:T76606产 地:中国大陆
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T76268Mca-VDQVDGW-Lys(Dnp)-NH2;化合物 Mca-VDQVDGW-Lys(Dnp)-NH2Mca-VDQVDGW-Lys(Dnp)-NH2
Mca-VDQVDGW-Lys(Dnp)-NH2, a fluorogenic substrate specific to caspase-7, facilitates the quantification of caspase-7 activity.
价 格:¥电议型 号:T76268产 地:中国大陆
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T76267Mca-PLGL-Dpa-AR-NH2;化合物 Mca-PLGL-Dpa-AR-NH2Mca-PLGL-Dpa-AR-NH2
Mca-PLGL-Dpa-AR-NH2 is a fluorescent peptide MMP substrate [1] .
价 格:¥电议型 号:T76267产 地:中国大陆