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T64061Mps1-IN-3 hydrochloride；化合物 Mps1-IN-3 hydrochlorideMps1-IN-3 hydrochloride
Mps1-IN-3 hydrochloride is a potent and selective inhibitor of Mps1 (IC50: 50 nM). mps1-IN-3 hydrochloride exhibits inhibitory effects on the proliferation of glioblastoma cells and effectively sensitizes glioblastomas to vincristine in an in situ xenograft tumor model.
价 格：￥电议型 号：T64061产 地：中国大陆
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T38696Rp-8-CPT-cAMPS；Rp-8-CPT-cAMPSRp-8-CPT-cAMPS
Rp-8-CPT-cAMPS is a powerful and competitive antagonist of cAMP-induced activation of cAMP-dependent protein kinase (PKA) I and II. Acting as a potent cAMP analog, Rp-8-CPT-cAMPS exhibits a preference for site A of RI over site A of RII. Additionally, it favors site B of RII over site B of RI. This compound effectively inhibits cAMP-dependent PKA activation and demonstrates selectivity in binding to specific sites within the protein kinase.
价 格：￥电议型 号：T38696产 地：中国大陆
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T38694Sp-8-CPT-cAMPS；Sp-8-CPT-cAMPSSp-8-CPT-cAMPS
Sp-8-CPT-cAMPS is a powerful and specific cAMP analog that activates cAMP-dependent protein kinase A (PKA I and PKA II) selectively and effectively. It exhibits a 153-fold preference for site A of RI over site A of RII, and a 59-fold preference for site B of RII over site B of RI.
价 格：￥电议型 号：T38694产 地：中国大陆
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T37050MPS1/TTK Inhibitor；MPS1/TTK InhibitorMPS1/TTK Inhibitor；MPS1/TTK Inhibitor
MPS1/TTK inhibitor is an inhibitor of monopolar spindle 1 (MPS1/TTK; IC50 = 5.8 nM), a kinase involved in mitotic spindle checkpoint signaling that is overexpressed in certain cancerous tumors. It inhibits MPS1 phosphorylation of kinetochore scaffold 1 (KNL1) and increases the rate of mitosis and the number of cells entering anaphase within 15 minutes, indicating MPS1 checkpoint inhibition, when used at a concentration of 100 nM. MPS1/TTK inhibitor (50 and 100 nM) increases the number of missegr
价 格：￥电议型 号：T37050产 地：中国大陆
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T36679Rp-cAMPS sodium salt；Rp-cAMPS sodium saltRp-cAMPS sodium salt
Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis by phosphodiesterases[1][2][3][4][5][6].
价 格：￥电议型 号：T36679产 地：中国大陆
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T36678Rp-8-CPT-cAMPS sodium；Rp-8-CPT-Cyclic AMP (sodium salt)Rp-8-CPT-cAMPS sodium
Rp-8-CPT-cAMP is a structural combination of the lipophilic and non-hydrolyzable cAMP analogs, 8-CPT-cyclic AMP and Rp-cyclic AMPS .[1] It functions as a site-selective inhibitor of protein kinase A (PKA) type I and II, with preference towards site A of type I and site B of type II.2 By occupying cAMP binding sites at the regulatory subunit of PKA, Rp-8-CPT-cAMP prevents the kinase holoenzyme from dissociative activation.[2],[3]
价 格：￥电议型 号：T36678产 地：中国大陆
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T36677Rp-8-bromo-Cyclic AMPS (sodium salt)；Rp-8-bromo-Cyclic AMPS (sodium salt)Rp-8-bromo-Cyclic AMPS (sod
Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II
价 格：￥电议型 号：T36677产 地：中国大陆
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T30486BMPSP；化合物 T30486BMPSP
BMPSP is a fluorescent DNA groove binding probe.
价 格：￥电议型 号：T30486产 地：中国大陆
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T28615Sp-cAMPS；化合物 T28615Rp-cAMPS TEA|||Rp cAMPS TEA|||Rp-cAMPS TEA salt|||Rp cAMPS TEA salt；Rp-cAMPS TEA|
Rp-cAMPS TEA salt is a cAMP-dependent protein kinase (PKA) activator.
价 格：￥电议型 号：T28615产 地：中国大陆
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T28090MpsBAY2a；化合物 T28090Mps BAY 2a|||Mps-BAY-2a；Mps BAY 2a|||Mps-BAY-2a
carcinoma cell proliferation.
价 格：￥电议型 号：T28090产 地：中国大陆
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T23865CCT-271850；化合物 T23865MPS1-IN-77|||MPS1IN77|||CCT271850|||CCT 271850|||MPS1 IN 77；MPS1-IN-77|||MPS1IN
CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.
价 格：￥电议型 号：T23865产 地：中国大陆
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T23252Rp-8-Br-PET-cGMPS化合物 T23252Rp 8 Br PET cGMPS|||Rp8BrPETcGMPS
cGMP-dependent protein kinase (PKG) inhibitor
价 格：￥电议型 号：T23252产 地：中国大陆
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T22621Rp-cAMPS；化合物 T22621cAMPS-Sp, triethylammonium salt；cAMPS-Sp, triethylammonium salt
Rp-cAMPS competitively inhibits the cAMP-induced activation of cAMP-dependent protein kinase (PKA).
价 格：￥电议型 号：T22621产 地：中国大陆
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T21871MMPSI；化合物MMPSICaspase-3/7 Inhibitor I；Caspase-3/7 Inhibitor I
MMPSI (Caspase-3/7 Inhibitor I) is a novel, non-peptide small molecule caspase 3 and caspase 7 inhibitor that reduces ischemic injury in isolated rabbit heart or cardiomyocytes and inhibits apoptosis of H16c2 cells in a concentration-dependent manner.MMPSI can be used to study cardioprotection and myocardial injury.
价 格：￥电议型 号：T21871产 地：中国大陆
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T21697Sp-Cyclic AMPS (sodium salt)；化合物 T21697Sp-Cyclic AMPS (sodium salt)
Sp-cAMPS sodium salt is an analog of cAMP that is a potent activator of cAMP-dependent PKA I and PKA II. Sp-cAMPS sodium salt is also a potent, competitive phosphodiesterase (PDE3A) inhibitor with a K i of 47.6 μM. Sp-cAMPS sodium salt binds the PDE10 GAF domain with an EC 50 of 40 μM [1] [2] [3].
价 格：￥电议型 号：T21697产 地：中国大陆
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T1839Mps1-IN-2；化合物Mps1-IN-2Mps1-IN-2
Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.
价 格：￥电议型 号：T1839产 地：中国大陆
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T17007TC-Mps1-12化合物 T17007TCMps112|||TC-Mps-1-12|||TC Mps1 12
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
价 格：￥电议型 号：T17007产 地：中国大陆
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T16130Mps1-IN-3；化合物Mps1-IN-3Mps1-IN-3
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
价 格：￥电议型 号：T16130产 地：中国大陆
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T14668BMPS；化合物 T14668BMPS
BMPS, a non-cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T14668产 地：中国大陆
