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产品数：86101
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T9014SKI-178resistant,SphK,cytotoxic,myeloid,Inhibitor,Apoptosis,leukemia,multi-drug,inhibit,SKI-178,canc
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during prolonged mitosis, mediated by SKI-178 leads to the simultaneous phosphorylation of the prosurvival Bcl-2 family members, Bcl-2 and Bcl-xl, as well as the phosphorylation and subsequent degradation of Mcl-1.
价 格：￥电议型 号：T9014产 地：中国大陆
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T79912-Hydroxycinnamic acidSARS coronavirus,Human immunodeficiency virus,inhibit,2Hydroxycinnamic acid,In
2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity.
价 格：￥电议型 号：T7991产 地：中国大陆
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T8799(E/Z)-IT-603GVHD,Inhibitor,Nuclear factor-kappaB,(E/Z)IT603,immunomodulatory,(E/Z) IT 603,disease,in
IT-603 is a cell-permeable c-Rel inhibitor (IC50: 3μM). IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding and transcriptional activity.
价 格：￥电议型 号：T8799产 地：中国大陆
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T6805Choline bitartrateCholine bitartrate,Inhibitor,Muscarinic acetylcholine receptor,inhibit,mAChR
Choline bitartrate is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcholine, a chemical that facilitates communication between the nerves and muscles.
价 格：￥电议型 号：T6805产 地：中国大陆
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T8760NNMTiNNMTi,inhibit,fusion,muSC,muscle stem cell,NNMT,Inhibitor,regenerative
NNMTi is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adipocytes 1-methylnicotinamide level (EC50 = 2.3 μM) without affecting related methyltransferases & enzymes in the NAD+ salvage pathway
价 格：￥电议型 号：T8760产 地：中国大陆
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T9072TuxobertinibTuxobertinib,inhibit,ErbB-1,EGFR,BDTX 189,BDTX189,mutants,Epidermal growth factor recept
BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity.
价 格：￥电议型 号：T9072产 地：中国大陆
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T7779Nelfinavirproduction,Human immunodeficiency virus,protease,myeloma,inhibit,AG-1341,phosphorylation,c
Nelfinavir is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.
价 格：￥电议型 号：T7779产 地：中国大陆
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TN1085Dehydrotumulosic acidinhibit,Inhibitor,Dehydrotumulosic acid
Dehydrotumulosic acid shows anti-inflammatory activity.
价 格：￥电议型 号：TN1085产 地：中国大陆
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T6715Valnemulin hydrochlorideAntibiotic,inhibit,Valnemulin hydrochloride,Valnemulin,Inhibitor,Bacterial
Valnemulin HCl is a broad-spectrum bacteriostatic agent inhibiting protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.
价 格：￥电议型 号：T6715产 地：中国大陆
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T8684SotorasibAMG 510,Ras,KRAS,covalent,Sotorasib,regression,mutation,Inhibitor,G12C,anti-tumour,inhibit,
AMG-510 is a selective and orally bioavailable KRAS G12C covalent inhibitor.
价 格：￥电议型 号：T8684产 地：中国大陆
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TQ0217Gomisin GHuman immunodeficiency virus,inhibit,HIV,Gomisin G,Inhibitor
Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9.
价 格：￥电议型 号：TQ0217产 地：中国大陆
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T6828ZL0420inhibit,Epigenetic Reader Domain,(E/Z)-ZL0420,BRD4,airway inflammation,immune response genes,Z
ZL0420 is a potent and selective bromodomain-containing protein 4 ( BRD4 ) inhibitor with nanomolar binding affinities to bromodomains (BDs) of BRD4. ZL0420 has IC 50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2.
价 格：￥电议型 号：T6828产 地：中国大陆
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T9019JHU37152JHU37152,inhibit,hM3Dq,Clozapine,Inhibitor,DREADD,Muscarinic acetylcholine receptor,mAChR,hM
JHU 37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 5 nM and 0.5 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
价 格：￥电议型 号：T9019产 地：中国大陆
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T7813α-MSHMelanocortin Receptor,hormone,αMSH,inhibit,Inhibitor,α MSH,neuroimmunomodulatory,inflammation,e
α-MSH is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
价 格：￥电议型 号：T7813产 地：中国大陆
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T8275(+)-IsopulegolInhibitor,Parasite,(+)-Isopulegol,inhibit,(+)Isopulegol,Terpenoid,phagostimulatory,fee
(+)-Isopulegol is a monoterpenoid from Mentha canadensis L.
价 格：￥电议型 号：T8275产 地：中国大陆
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TQ0248Alisol FInhibitor,Alisol F,immunosuppressive,triterpene,Hepatitis B virus,HBV,inhibit,virus
Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities.
价 格：￥电议型 号：TQ0248产 地：中国大陆
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TN7148Mukanadin C
Mukanadin C is a marine derived natural products found in Stylissa carteri.
价 格：￥电议型 号：TN7148产 地：中国大陆
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T8328STING agonist-1inhibit,TMEM173,Inhibitor,STING agonist 1,G 10,G-10,Stimulator of Interferon Genes,ST
STING agonist-1 is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
价 格：￥电议型 号：T8328产 地：中国大陆
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TP1309Gastric mucinAntibiotic,inhibit,Inhibitor,Gastric mucin,Bacterial
Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma.
价 格：￥电议型 号：TP1309产 地：中国大陆
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T7837SR8278Duchenne muscular dystrophy,inhibit,metabolism,biological rhythm,Alzheimer’s disease,SR-8278,S
SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM), blocking activation of the receptor by the synthetic agonist GSK 4112
价 格：￥电议型 号：T7837产 地：中国大陆
