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  • T62809NLRP3-IN-7；化合物 NLRP3-IN-7NLRP3-IN-7

    NLRP3-IN-7 (Compound 36) is a selective inhibitor of the NLRP3 inflammasome and is able to assemble the NLRP3 inflammasome.

    价 格：￥电议型 号：T62809产 地：中国大陆

  • T62808NLRP3-IN-6；化合物 NLRP3-IN-6NLRP3-IN-6

    NLRP3-IN-6 (Compound 34) is a selective inhibitor of the NLRP3 inflammasome.

    价 格：￥电议型 号：T62808产 地：中国大陆

  • T62221NLRP3-IN-8；化合物 NLRP3-IN-8NLRP3-IN-8

    NLRP3-IN-8 (compound 27), an orally active NLRP3 inflammasome inhibitor, directly binds to its target with an IC50 of 1.23 μM for IL-1β inhibition. It demonstrates robust metabolic stability in liver microsomes (t1/2 = 138.63 min) and exhibits minimal toxicity (against L02: IC50 > 100 μM) [1].

    价 格：￥电议型 号：T62221产 地：中国大陆

  • T61826NLRP3-IN-4；化合物 NLRP3-IN-4NLRP3-IN-4

    NLRP3-IN-4 is a highly efficient and orally bioavailable inhibitor of NLRP3 inflammasome, which exhibits strong anti-inflammatory properties specifically targeted towards colitis.

    价 格：￥电议型 号：T61826产 地：中国大陆

  • T61392NLRP3-IN-10；化合物NLRP3-IN-10ZVN26391；ZVN26391

    NLRP3-IN-10 (ZVN26391) is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.

    价 格：￥电议型 号：T61392产 地：中国大陆

  • T61132NLRP3-IN-11；NLRP3抑制剂11NLRP3-IN-11

    NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.

    价 格：￥电议型 号：T61132产 地：中国大陆

  • T60756NLRP3 antagonist 1；化合物 NLRP3 antagonist 1NLRP3 antagonist 1

    NLRP3 antagonist 1 shows potential for the cancer research that is a potent NLRP3 antagonist. NLRP3 is involved in the body´s intrinsic immunity against stress injury and pathogenic infections that is mainly expressed in macrophages and neutrophils [1].

    价 格：￥电议型 号：T60756产 地：中国大陆

  • T60563NLRP3/AIM2-IN-1；化合物 NLRP3/AIM2-IN-1NLRP3/AIM2-IN-1

    NLRP3/AIM2-IN-1 is an inhibitor of thermal sepsis (IC50 = 3.136 ± 0.7667 μM).

    价 格：￥电议型 号：T60563产 地：中国大陆

  • T60442NLRP3/AIM2-IN-3；化合物NLRP3/AIM2-IN-3NLRP3/AIM2-IN-3

    NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 is a potent inhibitor of NLRP3 and AIM2 inflammasome-dependent cell lysis with an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 inhibits LPS/nigericin NLRP3/AIM2-IN-3 inhibits LPS/nigericin-stimulated cell lysis in THP-1 macrophages with an IC50 value of 0.077 ± 0.008 μM. NLRP3/AIM2-IN-3

    价 格：￥电议型 号：T60442产 地：中国大陆

  • T60404NLRP3/AIM2-IN-2；化合物NLRP3/AIM2-IN-2NLRP3/AIM2-IN-2

    NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0233 μ M.

    价 格：￥电议型 号：T60404产 地：中国大陆

  • T39607NLRP3 modulators 1NLRP3 modulators 1NLRP3 modulators 1

    NLRP3 modulators 1 (WO2017184746A1, compound 107) is a potent modulator of NLRP3, capable of agonizing or partially agonizing the activity of NLRP3. This compound proves valuable in investigating conditions, diseases, or disorders where a reduction in LRP3 activity plays a role in the pathology.

    价 格：￥电议型 号：T39607产 地：中国大陆

  • T39552NLRP3-IN-5NLRP3-IN-5NLRP3-IN-5

    NLRP3-IN-5, a compound disclosed in WO2016131098, is an inhibitor of NLRP3 inflammasome. It consists of the chemical structure N-((4-chloro-2,6-dimethylphenyl)carbamoyl)-4-(2-hydroxypropan-2-l)furan-2-sulfonamide.

    价 格：￥电议型 号：T39552产 地：中国大陆

  • T3230NLRP3-IN-2；4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide|||NLRP3 Inflamm

    NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.

    价 格：￥电议型 号：T3230产 地：中国大陆

  • T28178NLRP3-IN-9；化合物NLRP3-IN-9INF-4E|||INF 4E|||INF4E；INF-4E|||INF 4E|||INF4E

    NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.

    价 格：￥电议型 号：T28178产 地：中国大陆

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