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T48531-Methylnicotinamide chloride1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydro
Niacin metabolite excreted via the urinary system.
价 格:¥电议型 号:T4853产 地:美洲
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T6220Nicotinamide riboside chlorideNicotinamide riboside chloride
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.
价 格:¥电议型 号:T6220产 地:美洲
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T838006-Biotin-17-NAD+ sodium;化合物 6-Biotin-17-NAD+ sodium6-Biotin-17-Nicotinamide adenine dinucleotide|||β
6-Biotin-17-NAD+, a biotinylated derivative of the signaling molecule and enzyme cofactor NAD+, is utilized in high-throughput screening (HTS) assays to measure the activity of mitochondrial complex I, also referred to as NADH dehydrogenase.
价 格:¥电议型 号:T83800产 地:中国大陆
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T837996-alkyne NAD+ sodium;化合物 6-alkyne NAD+ sodiumβ-Nicotinamide-N6-propargyladenine dinucleotide|||6-Par
6-alkyne NAD+, a clickable variant of the signaling molecule and enzyme cofactor NAD+, facilitates the fluorescent tagging for the detection of poly(ADP-ribose) polymerase (PARP) protein substrates.
价 格:¥电议型 号:T83799产 地:中国大陆
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T837988-bromo NAD+ sodium;化合物 8-bromo NAD+ sodium8-bromo Nicotinamide adenine dinucleotide|||N(8-bromo-A)D
8-Bromo NAD+ serves as a prodrug for the cyclic ADP-ribose (cADPR) inhibitor, 8-bromo cADPR, undergoing conversion to its active form by the enzyme CD38. At a concentration of 1 mM, it effectively inhibits the rise in intracellular calcium levels and chemotaxis triggered by N-formyl-Met-Leu-Phe (fMLP) in mouse bone marrow-derived neutrophils. Furthermore, when applied at 100 ?M, this compound reduces LPS-induced nitrite production and decreases the secretion of TNF-α and IL-2 in mouse primary mi
价 格:¥电议型 号:T83798产 地:中国大陆
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T83675Thio-NAD;化合物 Thio-NADThionicotinamide NAD|||Thionicotinamide adenine dinucleotide;Thionicotinamide N
Thio-NAD, a thione-modified derivative of the signaling molecule and enzyme cofactor NAD+, can substitute for NAD+ as a cofactor in alkaline phosphatase (ALP) enzyme activity assays. It is utilized as a substrate in dual-enzyme cycling ELISA for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, or surface glycoprotein, and live M. tuberculosis in patient sputum. Thio-NAD is characterized by its absorbance at 405 nm, distinguishing it from other cof
价 格:¥电议型 号:T83675产 地:中国大陆
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T7869N-(Hydroxymethyl)nicotinamide;N-羟甲基烟酰胺Nicoform|||N-hydroxymethylnicotinamide|||Bilamid|||Nikomethami
N-(Hydroxymethyl)nicotinamide (Bilamid) is an antimicrobial agent.
价 格:¥电议型 号:T7869产 地:中国大陆
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T78408Nicotinamide 1,N6-ethenoadenine dinucleotide;化合物 Nicotinamide 1,N6-ethenoadenine dinucleotideε-NAD;ε
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD), a fluorescent NAD analogue, functions as a substrate in bacterial toxin-catalyzed G-ADP ribosylation of G-proteins involved in signal transduction. It is also applicable as a fluorescent substrate in ADP ribosylation reaction studies [1].
价 格:¥电议型 号:T78408产 地:中国大陆
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T77253β-Nicotinamide adenine dinucleotide reduced dipotassium;化合物 β-Nicotinamide adenine dinucleotide redu
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active, reduced coenzyme that functions as a donor of ADP-ribose units in ADP-ribosylation reactions, and as a precursor of cyclic ADP-ribose. It also serves as a regenerative electron donor in vital cellular energy metabolism processes, including glycolysis, β-oxidation, and the tricarboxylic acid (TCA) cycle [1].
价 格:¥电议型 号:T77253产 地:中国大陆
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T75456-Aminonicotinamide;6-氨基烟酰胺6-Aminonicotinamide
6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme.
价 格:¥电议型 号:T7545产 地:中国大陆
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T72188Nicotinamide Hydrochloride;化合物 Nicotinamide HydrochlorideNiacinamide Hydrochloride|||Nicotinic acid
Nicotinamide Hydrochloride is a form of vitamin B3 or niacin that inhibits sirtuin 2 ( SIRT2 ) activity in vitro , with an EC 50 of 2 μM. Nicotinamide Hydrochloride inhibits up to 90% melanoma cell number and increases cellular NAD + , ATP, ROS levels. Nicotinamide Hydrochloride inhibts tumor growth in vivo and improves survival of melanoma-bearing mice, which can be used for the research of skin cancers such as melanoma [1] .
价 格:¥电议型 号:T72188产 地:中国大陆
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T69395Nicotinamide-d4;化合物 Nicotinamide-d4Nicotinamide-d4
Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized in vivo or obtained through the diet. It is a precursor in the synthesis of the metabolic cofactor NAD+ and an inhibitor of sirtuin 1 (SIRT1; IC50 = <50 ?M). Nicotinamide (10 ?M) increases the activity of serine palmitoyltransferase (SPT) and the biosynthesis of ceramide, glucosyl
价 格:¥电议型 号:T69395产 地:中国大陆
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T665826-Methylnicotinamide;6-甲基烟酰胺6-Methylnicotinamide
6-Methylnicotinamide is a derivative of nicotinamide, an endogenous metabolite. 6-Methylnicotinamide is used to make co-crystals/salts. In the acute phase of cerebral hemorrhage (ICH), a sudden increase in 6-Methylnicotinamide exacerbates neurological damage.6-Methylnicotinamide can be used to make co-crystals/salts.6-Methylnicotinamide can be used to make co-crystals/salts.
价 格:¥电议型 号:T66582产 地:中国大陆
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T65332N-(2-Hydroxyethyl)nicotinamide;化合物 N-(2-Hydroxyethyl)nicotinamideN-(2-Hydroxyethyl)nicotinamide
N-(2-Hydroxyethyl)nicotinamide is a useful organic compound for research related to life sciences. The catalog number is T65332 and the CAS number is 6265-73-2.
价 格:¥电议型 号:T65332产 地:中国大陆
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T6220Nicotinamide riboside chloride烟酰胺核糖氯酸盐烟酰胺核糖氯酸盐|||烟酰胺核苷
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.
价 格:¥电议型 号:T6220产 地:中国大陆
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T4853TRIA-662;3-氨基甲酰-1-甲基氯化吡啶3-Carbamoyl-1-methylpyridinium Chloride|||1-Methylnicotinamide chloride|||1-
TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system.
价 格:¥电议型 号:T4853产 地:中国大陆
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T4721β-Nicotinamide mononucleotide;烟酰胺单核苷酸NMN|||β-NM;NMN|||β-NM|||β烟酰胺单核苷酸|||烟酰胺单核苷酸
β-Nicotinamide mononucleotide (β-NM) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD biosynthesis. Instead of the deamidation to nicotinic acid, nicotinamide is directly converted to β-Nicotinamide mononucleotide by nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12). The enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1), which i
价 格:¥电议型 号:T4721产 地:中国大陆
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T40060Nicotinamide riboside malate;烟酰胺核糖苹果酸盐Nicotinamide riboside malate
Nicotinamide riboside malate is an orally active NAD+ precursor that elevates NAD+ levels and stimulates the activity of SIRT1 and SIRT3. Functioning as a vitamin B3 (niacin) source, it augments oxidative metabolism and provides protection against metabolic abnormalities induced by a high-fat diet. Additionally, Nicotinamide riboside malate mitigates cognitive decline in a genetically modified mouse model of Alzheimer´s disease.
价 格:¥电议型 号:T40060产 地:中国大陆
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T40059Nicotinamide riboside tartrate;烟酰胺核糖酒石酸盐Nicotinamide riboside tartrate
Nicotinamide riboside tartrate (NRT) is an oral NAD+ precursor that raises NAD+ levels, activates SIRT1 and SIRT3, and serves as a vitamin B3 (niacin) source. NRT also improves oxidative metabolism and protects against metabolic abnormalities induced by a high-fat diet. Furthermore, NRT mitigates cognitive decline in a transgenic mouse model of Alzheimer´s disease.
价 格:¥电议型 号:T40059产 地:中国大陆
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T370461-Methyl-1,4-dihydronicotinamide;1-Methyl-1,4-dihydronicotinamide1-Methyl-1,4-dihydronicotinamide
1-Methyl-1,4-dihydronicotinamide is a nicotinamide derivative. Its product number is T37046 and CAS number is 17750-23-1.
价 格:¥电议型 号:T37046产 地:中国大陆