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T1474Otilonium bromide奥替溴铵;SP63;Octylonium bromide
Otilonium Bromide, an antimuscarinic, is utilized as a spasmolytic agent.
价 格:¥电议型 号:T1474产 地:中国大陆
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T13809P62-mediated mitophagy inducerPMI
P62-mediated mitophagy inducer is a regulator of mitophagy .
价 格:¥电议型 号:T13809产 地:中国大陆
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T13119TenalisibRP6530
Tenalisib (RP6530) is a potent and selective inhibitor of PI3Kδ and PI3Kγ(IC50 values of 25 and 33 nM, respectively.)
价 格:¥电议型 号:T13119产 地:中国大陆
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T13119TenalisibTenalisib,RP6530,
Tenalisib (RP6530) is a potent and selective inhibitor of PI3Kδ and PI3Kγ(IC50 values of 25 and 33 nM, respectively.)
价 格:¥电议型 号:T13119产 地:美洲
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T13120Tenalisib R EnantiomerTenalisib R Enantiomer,RP6530 R Enantiomer,
Tenalisib R Enantiomer is an R enantiomer of Tenalisib .
价 格:¥电议型 号:T13120产 地:美洲
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T13737iRucaparib-AP6iRucaparib-AP6
iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1. iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach.
价 格:¥电议型 号:T13737产 地:美洲
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T14335ASP6432ASP6432
ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively.
价 格:¥电议型 号:T14335产 地:美洲
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T1474Otilonium bromideOtilonium bromide,SP63,Octylonium bromide
Otilonium Bromide, an antimuscarinic, is utilized as a spasmolytic agent.
价 格:¥电议型 号:T1474产 地:美洲
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T14943CGP60474CGP60474
CGP60474 is an inhibitor of VEGFR-2 (IC50: 84 nM). CGP60474 also is an inhibitor of ATP-competitive PKC.
价 格:¥电议型 号:T14943产 地:美洲
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T1520Aliskiren hemifumarateAliskiren hemifumarate,CGP60536B,SPP 100
Aliskiren Hemifumarate is an orally active nonpeptide renin inhibitor with antihypertensive activity.
价 格:¥电议型 号:T1520产 地:美洲
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T2335EbastineEbastine,RP64305,LAS-W 090
Ebastine (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tissue without a central side effect, i. e not ca
价 格:¥电议型 号:T2335产 地:美洲
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T2543CabazitaxelCabazitaxel,RPR-116258A,taxoid XRP6258
Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel.
价 格:¥电议型 号:T2543产 地:美洲
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T4695CP671305CP671305
CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.
价 格:¥电议型 号:T4695产 地:美洲
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T5400Q203Q203,IAP6,Telacebec
Q203 is a novel potent anti-tuberculosis agent targeting cytochrome b subunit qcrB and inhibits M. tuberculosis H37Rv (MIC50: 2.7 nM).
价 格:¥电议型 号:T5400产 地:美洲
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T6091CP-673451CP-673451,CP673451,CP 673451
CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other angiogenic receptors.
价 格:¥电议型 号:T6091产 地:美洲
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T83865HP661;化合物 HP661HP661
HP661, a selective inhibitor of mitochondrial complex I (NADH dehydrogenase), impedes complex I activity by 77.6% at 1 ?M, demonstrating lesser inhibition towards complex III (28.1%) and no inhibitory effects on complexes II and IV. It notably decreases the viability of human lung cancer cells—H460, NCI H441, and trametinib-resistant A549 cells (IC50s = 10.6, 29.7, and 15.1 nM, respectively)—which exhibit high levels of oxidative phosphorylation. In contrast, it shows minimal activity against NC
价 格:¥电议型 号:T83865产 地:中国大陆
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T83849OP-145 TFA;化合物 OP-145 TFAacetyl-IGKEFKRIVERIKRFLRELVRPLR-amide|||P60.4-Ac;acetyl-IGKEFKRIVERIKRFLREL
OP-145, a derivative of the antimicrobial peptide LL-37, is a synthetic antimicrobial peptide showing activity against E. coli, P. aeruginosa, C. albicans, and A. niger, with minimum inhibitory concentrations (MICs) of 2, 3, 6, and 18 ?M, respectively. Utilizing poly(lactic-co-glycolic acid) (PLGA) microspheres loaded with OP-145 effectively prevents biofilm formation in a mouse model of bone infection, which is initiated by surgical femoral fracture and subsequent bacterial inoculation at the f
价 格:¥电议型 号:T83849产 地:中国大陆
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T83700IRBP (651-670) (human) TFA;化合物 IRBP (651-670) (human) TFAIRBP651-670|||Interphotoreceptor Retinoid-B
Interphotoreceptor retinoid-binding protein (651-670) (IRBP651-670), a peptide fragment of retinoid-binding protein 3 (also known as IRBP), plays a crucial role in the visual cycle by facilitating the transport of retinol and retinal between photoreceptor cells and the retinal pigment epithelium. This transport is essential for the regeneration of pigments necessary for vision. When administered at a dose of 300 ?g/animal, IRBP651-670 induces autoimmune uveoretinitis in C57BL/6 mice, a model pos
价 格:¥电议型 号:T83700产 地:中国大陆
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T8314RP-64477;化合物RP64477RP64477;RP64477
RP-64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.
价 格:¥电议型 号:T8314产 地:中国大陆