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产品数:86101
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TN1124Neoeriocitrinphosphatase,Neoeriocitrin,inhibit,Inhibitor,cell,PC12,MC3T3-E1,alkaline,?proliferation,
Neoeriocitrin is a natural product isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor.
价 格:¥电议型 号:TN1124产 地:中国大陆
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TQ0252BAR502GPCR19,BAR 502,G protein-coupled Bile Acid Receptor 1,BAR-502,BAR502,Autophagy,GPBAR1,NR1H4,In
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
价 格:¥电议型 号:TQ0252产 地:中国大陆
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T64339Apcin A HCLApcin A HCL
Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].
价 格:¥电议型 号:T64339产 地:中国大陆
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T9407Rasarfinbreast,cancer,Inhibitor,TNBC,Ras,negative,GPCR,inhibit,Rasarfin,internalization,triple
Rasarfin inhibits Ras and ARF6.
价 格:¥电议型 号:T9407产 地:中国大陆
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T6889MI-136PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen
MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.
价 格:¥电议型 号:T6889产 地:中国大陆
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T8983TSPCInhibitor,gibberellin,TSPC,inhibit,perception,phytohormone
TSPC is an inhibitor for GA perception by in vitro and in planta evaluations.
价 格:¥电议型 号:T8983产 地:中国大陆
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T23801WCK-4234 sodiuminhibit,carbapenemases,antibacterial,KPC enzymes,diazabicyclooctanes (DBOs),Enterobac
WCK-4234 sodium is an inhibitor of β-lactamase can be used in studies targeting MDR infections. WCK-4234 sodium inhibits class A, C, and D β-lactamases and OXA carbapenemases.
价 格:¥电议型 号:T23801产 地:中国大陆
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T9595LP-261NCI-H522,tubulin polymerization,tumor,SW-620,BXPC-3,H522,anti-mitotic,inhibit,LP261,MCF-7,Inhi
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.
价 格:¥电议型 号:T9595产 地:中国大陆
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T11366GarcinolInhibitor,HATs,PCAF,anti-cancer,Garcinol,Endogenous Metabolite,indica,anti-inflammatory,inhi
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively.
价 格:¥电议型 号:T11366产 地:中国大陆
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T13804OPC-28326OPC28326,OPC 28326
OPC-28326 is a specific an α2-adrenergic receptor antagonist and acts as a peripheral vasodilator. OPC-28326 inhibits α2A-, α2B- and α2C-adrenoceptors with Ki of 2040, 285, and 55?nM, respectively.
价 格:¥电议型 号:T13804产 地:中国大陆
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T8188PodophyllotoxoneInhibitor,DU145,inhibit,Podophyllotoxone,cancer,Microtubule/Tubulin,PC3,cells,prosta
Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro.
价 格:¥电议型 号:T8188产 地:中国大陆
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T6S1740Nardosinonecells,Nardosinone,Neurite,substances,PC12D,outgrowth-promoting,neuritogenic,inhibit,MAPK,
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and stau
价 格:¥电议型 号:T6S1740产 地:中国大陆
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T10989Dehydroaripiprazoleinhibit,antipsychotic,OPC14857,OPC 14857,Dehydroaripiprazole,CYP3A4,Inhibitor,Met
Dehydroaripiprazole is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mainly forms dehydroaripiprazole. Dehydroaripiprazole has antipsychotic activity equivalent to aripiprazole.
价 格:¥电议型 号:T10989产 地:中国大陆
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T8561Apcinligase,pocket,anaphase-promoting,Apcin,recognition,complex,Inhibitor,Cdc20,Anaphase promoting c
Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blocking mitotic exit and being synergistically amplified by co-addition of Ts-Arg-OMe.
价 格:¥电议型 号:T8561产 地:中国大陆
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T37428TRPC6-PAM-C20
TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 with an EC50 of 2.37 μM. TRPC6-PAM-C20 enhances OAG-induced platelet aggregation.
价 格:¥电议型 号:T37428产 地:中国大陆
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TN7029(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol(2S)1Opcoumaroyl2Oacetyl3OβDglucopyran
(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol is a chemical compound.
价 格:¥电议型 号:TN7029产 地:中国大陆
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T9446KB-0742 dihydrochlorideKB0742,inhibit,CDK,CDK9,KB-0742,KB 0742,Ser7,Ser2,CRPC,KB 0742 dihydrochlorid
KB-0742 dihydrochloride is a potent, selective and orally inhibitor of ?CDK9.
价 格:¥电议型 号:T9446产 地:中国大陆
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TP1906L1DPC AJ1951 acetateDPC AJ1951 acetate
DPC-AJ1951 acetate, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 acetate in ex vivo and in vivo assays of bone resorption[1].
价 格:¥电议型 号:TP1906L1产 地:中国大陆
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T17921(S,R,S)-AHPC-PEG4-N3
(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17921产 地:中国大陆
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T67776PCSK9-IN-11PCSK9IN11
PCSK9-IN-11 (compound 5r) is a potent PCSK9 inhibitor with oral activity. PCSK9-IN-11 shows inhibitory activity of PCSK9 transcription in HepG2 cells (IC50= 5.7 μM). PCSK9-IN-11 can increase LDL receptor (LDLR) protein level. PCSK9-IN-11 can be used for atherosclerosis research.
价 格:¥电议型 号:T67776产 地:中国大陆