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T15238Epoprostenol sodiumEpoprostenol sodium,Prostaglandin I2 sodium salt,Prostacyclin sodium salt
Epoprostenol sodium as a potent inhibitor of platelet aggregation is used in pulmonary hypertension and transplantation. Epoprostenol sodium, the synthetic form of the natural prostaglandin derivative prostacyclin, is registered worldwide for the treatmen
价 格：￥电议型 号：T15238产 地：美洲
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T4546Dinoprost TromethamineDinoprost Tromethamine,PGF2α THAM,Prostaglandin F2α THAM
Dinoprost(Prostaglandin F2α) tromethamine salt is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
价 格：￥电议型 号：T4546产 地：美洲
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T5014Prostaglandin E2 (PGE2)Prostaglandin E2 (PGE2),Dinoprostone,Prostaglandin E2
Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammat
价 格：￥电议型 号：T5014产 地：美洲
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T83779EP4 Antagonist 14；化合物 EP4 Antagonist 14Prostaglandin E2 Receptor 4 Antagonist 14|||PGE2 Receptor 4 A
EP4 antagonist 14 is a prostaglandin E2 receptor subtype EP4 antagonist, demonstrating an IC50 of 1.1 nM in a HEK293 human receptor reporter assay and blocking β-arrestin recruitment due to PGE2 with an IC50 of 0.9 nM. At 10 ?M, it reduces PGE2-stimulated mRNA levels of Il-4, macrophage mannose receptor 1 (Mrc1), chitinase-like protein 3 (Chil3), chemokine (C-X-C) motif ligand 1 (Cxcl1), triggering receptor expressed on myeloid cells 2 (Trem2), and arginase-1 (Arg1) in RAW 264.7 macrophages. Whe
价 格：￥电议型 号：T83779产 地：中国大陆
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T83773Prostaglandin E2 Inhibitor 3；化合物 Prostaglandin E2 Inhibitor 3PGE2 Inhibitor 3；PGE2 Inhibitor 3
Prostaglandin E2 (PGE2) inhibitor 3 is a selective inhibitor targeting microsomal prostaglandin E synthase-1 (mPGES-1; IC50 = 0.2 ?M), demonstrating greater selectivity for mPGES-1 over COX-1, COX-2, 5-lipoxygenase (5-LO), and soluble epoxide hydrolase (sEH) in assays at 10 ?M. This compound effectively reduces IL-1β-induced PGE2 production in A549 cells and decreases LPS-induced IL-6 and PGE2 in J774A.1 macrophages at concentrations of 10 and 1 ?M, respectively. Additionally, it blocks the prod
价 格：￥电议型 号：T83773产 地：中国大陆
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T836622,3-dinor-8-iso Prostaglandin F1α；化合物 2,3-dinor-8-iso Prostaglandin F1α2,3-dinor-8-iso PGF1α|||2,3-d
2,3-Dinor-8-iso Prostaglandin F1α (2,3-dinor-8-iso PGF1α), an isoprostane and active metabolite of arachidonic acid deriving its formation from non-enzymatic free radical peroxidation, acts as an active metabolite of the platelet aggregation inhibitor 8-iso PGF2α. This compound exhibits vasoconstrictive properties in isolated porcine retinal and brain microvessels with EC50 values of 12.8 and 18.5 nM, respectively, yet it does not cause contraction in isolated rat aortic rings at a concentration
价 格：￥电议型 号：T83662产 地：中国大陆
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T78584Prostaglandin D3；化合物 Prostaglandin D3PGD3；PGD3
Prostaglandin D3 (PGD3) functions as an inhibitor of platelet aggregation and modulates autonomic neurotransmission in humans [1].
价 格：￥电议型 号：T78584产 地：中国大陆
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T7858215-keto-Prostaglandin E2；化合物 15-keto-Prostaglandin E215-keto-PGE2；15-keto-PGE2
15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast cancer cell growth and progression. Additionally, it binds and stabilizes the EP2 and EP4 receptors, activates PPAR-γ, and promotes fungal growth [1] [2] [3].
价 格：￥电议型 号：T78582产 地：中国大陆
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T73782Prostaglandin J2；化合物 Prostaglandin J2Prostaglandin J2
Prostaglandin J2 (PGJ2), a derivative of Prostaglandin D2 (PGD2), serves as a potent agonist for PGD2 receptors (DP), exhibiting affinity constants (K i) of 0.9 nM and 6.6 nM for hDP and hCRTH2 receptors, respectively. It activates cyclic AMP production with an EC50 of 1.2 nM, induces oxidative stress, neuronal apoptosis, and promotes the accumulation of ubiquitinated (Ub) proteins. Notably, PGJ2´s neurotoxic properties are implicated in the progression of neurodegenerative diseases such a
价 格：￥电议型 号：T73782产 地：中国大陆
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T718515-trans-Prostaglandin E2；化合物 5-trans-Prostaglandin E25-trans-Prostaglandin E2
5-trans-Prostaglandin E2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator. It also inhibits platelet aggregation in human PRP.
价 格：￥电议型 号：T71851产 地：中国大陆
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T6399AZD1981；化合物AZD1981Prostaglandin Receptor|||AZD 1981|||AZD1981|||Inhibitor|||AZD 1981|||AZD-1981|||AZ
AZD1981 is an effective and specific CRTh2 (DP2) receptor antagonist (IC50: 4 nM), showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. AZD1981 has been used in trials studying the treatment and basic science of Asthma, Postmenopausal, Pharmakokinetic, Asthma Patients, and Drug Interaction, among others.
价 格：￥电议型 号：T6399产 地：中国大陆
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T5014Prostaglandin E2；前列腺素 E2PGE2|||Dinoprostone|||Prostaglandin E2 (PGE2)；地诺前列酮|||前列腺素 E2|||PGE2|||Dinop
Prostaglandin E2 (PGE2) is a naturally occurring hormone involved in a variety of physiological processes in the body, including smooth muscle contraction and relaxation, regulation of vasodilatation and constriction, regulation of blood pressure, and inflammatory regulation.
价 格：￥电议型 号：T5014产 地：中国大陆
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T41328Delta-12-Prostaglandin J2；化合物 Delta-12-Prostaglandin J2Delta-12-Prostaglandin J2
Delta-12-Prostaglandin J2 has a wide range of applications in life science related research.
价 格：￥电议型 号：T41328产 地：中国大陆
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T38389Prostaglandin D2 Ethanolamide；Prostaglandin D2 EthanolamideProstaglandin D2 Ethanolamide；Prostagland
Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor. It increases the frequency of minia
价 格：￥电议型 号：T38389产 地：中国大陆
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T3834211-deoxy Prostaglandin E2；11-deoxy Prostaglandin E211-deoxy Prostaglandin E2；11-deoxy Prostaglandin
11-deoxy Prostaglandin E2 (11-deoxy PGE2) is a stable, synthetic analog of PGE2 . In contrast to PGE2 which has bronchodilation effects, 11-deoxy PGE2 is a powerful bronchoconstrictor and contracts human respiratory tract smooth muscle with potencies ranging from 5 to 30 times higher than PGF2α .
价 格：￥电议型 号：T38342产 地：中国大陆
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T38198Prostaglandin F2α methyl ester；Prostaglandin F2α methyl esterProstaglandin F2α methyl ester
Prostaglandin F2α methyl ester is a highly lipid-soluble PGF2α analog used to maintain low intraocular pressure.
价 格：￥电议型 号：T38198产 地：中国大陆
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T38197Prostaglandin F2α Alcohol；Prostaglandin F2α AlcoholProstaglandin F2α Alcohol
Prostaglandin F2α Alcohol is a PGF2α (T15133) analogue. Prostaglandin F2α Alcohol is an orally active prostaglandin F receptor (FP receptor) agonist.
价 格：￥电议型 号：T38197产 地：中国大陆
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T38196Prostaglandin F2α isopropyl ester；Prostaglandin F2α isopropyl esterProstaglandin F2α isopropyl ester
PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application in studies on intraocular pressure. The ester functionality is readily hydrolyzed in vivo to release the active compound PGF2α. When administered topically to the eyes of cynomolgus monkeys, a 5 μg dose reduces intraocular pressure by 68% after the fourth day of treatment.
价 格：￥电议型 号：T38196产 地：中国大陆
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T38195Prostaglandin F2α Ethanolamide；Prostaglandin F2α EthanolamideProstaglandin F2α Ethanolamide；Prostagl
Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide congeners of the classical PGs. PGF2α-EA has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2α-EA is a potent dilator (
价 格：￥电议型 号：T38195产 地：中国大陆
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T38194Prostaglandin E3；Prostaglandin E3PGE3；PGE3
Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. [1] In human ocular tissue, it comprises 2.4% of the COX products formed. [1] When applied to the eyes of a rabbit, a 1 µg dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.[2]
价 格：￥电议型 号：T38194产 地：中国大陆
