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T2236RU58841RU58841,HMR-3841,PSK-3841
RU 58841 is a specific androgen receptor antagonist or anti-androgen; RU 58841 has a significant effect on hair regrowth.
价 格:¥电议型 号:T2236产 地:美洲
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T6192AlogliptinAlogliptin,SYR-322,
Alogliptin(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
价 格:¥电议型 号:T6192产 地:美洲
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T82602DCI-Br-3;化合物 DCI-Br-3DCI-Br-3
DCI-Br-3 serves as a swift and selective probe with high sensitivity for thiol monitoring in the epileptic brain, exhibiting an excitation wavelength (λex) of 537 nm and an emission wavelength (λem) of 675 nm. It is also capable of efficiently penetrating the blood-brain barrier (BBB) [1].
价 格:¥电议型 号:T82602产 地:中国大陆
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T81710N-Acetyldopamine dimer-3;化合物 N-Acetyldopamine dimer-3N-Acetyldopamine dimer-3
N-Acetyldopamine dimer-3 (Compound 11), a naturally occurring chemical, is present in the species Aspongopus chinensis [1].
价 格:¥电议型 号:T81710产 地:中国大陆
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T81384PROTAC BRD9 Degrader-3;化合物 PROTAC BRD9 Degrader-3PROTAC BRD9 Degrader-3
PROTAC BRD9 Degrader-3 is a bifunctional degrader targeting BRD9, utilized in cancer research.
价 格:¥电议型 号:T81384产 地:中国大陆
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T81318R-30-Hydroxygambogic acid;化合物 R-30-Hydroxygambogic acidR-30-Hydroxygambogic acid
R-30-Hydroxygambogic acid, a polyprenylated xanthone epimer isolated from the gamboge of Garcinia hanburyi, exhibits cytotoxicity against human leukemia K562 cell lines, with IC50 values of 2.89 μM for the resistant strain (K562/R) and 1.27 μM for the sensitive strain (K562/S). This compound is utilized in cancer research [1].
价 格:¥电议型 号:T81318产 地:中国大陆
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T79891Androgen receptor degrader-3;化合物 Androgen receptor degrader-3Androgen receptor degrader-3
Androgen Receptor Degrader-3 (ARD-3) is a compound that inhibits androgen receptor signaling and promotes the degradation of the receptor, with potential applications in prostate cancer research [1].
价 格:¥电议型 号:T79891产 地:中国大陆
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T79437NAMPT degrader-3;化合物 NAMPT degrader-3NAMPT degrader-3
NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism. It exhibits cytotoxic properties and inhibits the proliferation of A2780 cells [1].
价 格:¥电议型 号:T79437产 地:中国大陆
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T79277Cysteine protease inhibitor-3;化合物 Cysteine protease inhibitor-3Cysteine protease inhibitor-3
Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM), PfW2 (IC50 = 1.05 μM), PfFP2 (IC50 = 3.5 μM), and PfFP3 (IC50 = 4.9 μM). It demonstrates efficacy against both drug-sensitive and drug-resistant parasites [1].
价 格:¥电议型 号:T79277产 地:中国大陆
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T79148PROTAC KRAS G12C degrader-3;化合物 PROTAC KRAS G12C degrader-3PROTAC KRAS G12C degrader-3
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].
价 格:¥电议型 号:T79148产 地:中国大陆
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T79102β-Catenin modulator-3;化合物 β-Catenin modulator-3β-Catenin modulator-3
β-Catenin modulator-3 (compound IIa-112), an oxazole and thiazole-based chemical entity, serves as a potent and selective modulator of β-Catenin [1].
价 格:¥电议型 号:T79102产 地:中国大陆
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T79067PROTAC BTK Degrader-3;化合物 PROTAC BTK Degrader-3PROTAC BTK Degrader-3
PROTAC BTK Degrader-3 is a potent degrader of Bruton´s tyrosine kinase (BTK), exhibiting a DC50 (median degradation concentration) of 10.9 nM in Mino cells. This compound shows promise for research into B-cell malignancies, such as chronic lymphoid malignancies [1].
价 格:¥电议型 号:T79067产 地:中国大陆
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T78650Nrf2 activator-3;Nrf2 激活剂3Nrf2 activator-3
Nrf2 activator-3 is a potent Nrf2 activator with potential anti-inflammatory, antioxidant and anti-tumor activity, which can be used to study neurological and immune-related diseases.
价 格:¥电议型 号:T78650产 地:中国大陆
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T75870PR-39 TFA;化合物 PR-39 TFAPR-39 TFA
PR-39 TFA, a natural peptide rich in proline and arginine with antibacterial properties, acts as a noncompetitive, reversible, and allosteric inhibitor of the proteasome. It specifically attaches to the α7 subunit of the proteasome, preventing the degradation of the NF-κB inhibitor IκBα through the ubiquitin-proteasome pathway. Additionally, PR-39 TFA promotes angiogenesis, suppresses inflammatory responses, and notably decreases myocardial infarct size in mice [1] [2].
价 格:¥电议型 号:T75870产 地:中国大陆
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T752175’-DMTr-3’dA(Bz)-methylphosphonami dite;化合物 5’-DMTr-3’dA(Bz)-methylphosphonami dite5’-DMTr-3’dA(Bz)-
5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits wide-ranging antitumor activity, specifically targeting indolent lymphoid malignancies. Its anticancer effects stem from the inhibition of DNA synthesis and the induction of apoptosis, among other mechanisms [1].
价 格:¥电议型 号:T75217产 地:中国大陆
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T75024ChoKα inhibitor-3;化合物 ChoKα inhibitor-3ChoKα inhibitor-3
ChoKα Inhibitor-3, a sulfur-containing choline kinase inhibitor, effectively inhibits HChoK α1 with an IC50 value of 0.66 μM and possesses the capability to induce apoptosis. This compound is utilized in cancer research [1].
价 格:¥电议型 号:T75024产 地:中国大陆
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T75020PROTAC SOS1 degrader-3;化合物 PROTAC SOS1 degrader-3PROTAC SOS1 degrader-3
PROTAC SOS1 Degrader-3 is a potent agent specifically designed to target and degrade SOS1 via the ubiquitin-proteasome system [1].
价 格:¥电议型 号:T75020产 地:中国大陆
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T74601Antitumor photosensitizer-3;化合物 Antitumor photosensitizer-3Antitumor photosensitizer-3
Antitumor Photosensitizer-3 (Compound I), a chlorin derivative, effectively induces apoptosis and necrosis in tumor cells upon exposure to 650 nm laser irradiation. This compound demonstrates reduced skin phototoxicity compared to the positive reference m-THPC in vivo [1].
价 格:¥电议型 号:T74601产 地:中国大陆
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T73999PROTAC Bcl-xL degrader-3;化合物 PROTAC Bcl-xL degrader-3PROTAC Bcl-xL degrader-3
PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader.
价 格:¥电议型 号:T73999产 地:中国大陆
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T72924VEGFR-3-IN-1;VEGFR-3抑制剂1VEGFR-3-IN-1
VEGFR-3-IN-1 is a novel potent and selective VEGFR3 inhibitor with an IC50 of 110.4 nM.VEGFR-3-IN-1 possesses antitumor activity, inactivates the VEGFR3 signaling pathway, and inhibits the proliferation and migration of VEGF-C-induced human dermal lymphatic endothelial cells (HDLEC), MDA-MB-231 and MDA-MB-436 cells. MB-436 cells and inhibited the proliferation and migration of human dermal lymphatic endothelial cells (HDLEC), MDA-MB-231 and MDA-MB-436 cells.
价 格:¥电议型 号:T72924产 地:中国大陆