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T79104β-Catenin modulator-5；化合物 β-Catenin modulator-5β-Catenin modulator-5
β-Catenin Modulator-5 (Compound IIa-84), an oxazole and thiazole-based compound, serves as a potent and selective modulator of β-Catenin [1].
价 格：￥电议型 号：T79104产 地：中国大陆
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T78979HIV-1 inhibitor-56；化合物 HIV-1 inhibitor-56HIV-1 inhibitor-56
HIV-1 inhibitor-56 (compound 12126065) is a potent non-nucleoside reverse transcriptase inhibitor with significant antiviral activity against wild-type HIV-1, exhibiting an EC50 value of 0.24 nM in TZM cells. Notably, this compound is capable of penetrating the blood-brain barrier [1].
价 格：￥电议型 号：T78979产 地：中国大陆
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T78925HIV-1 inhibitor-58；化合物 HIV-1 inhibitor-58HIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type strain IIIB and NNRTI-resistant strains like K103N and E138K in MT-4 cells at an EC50 of less than 50 nM. Additionally, it inhibits CYP2C9 and CYP2C19 with IC50 values of 2.06 μM and 1.91 μM, respectively. This compound is utilized in HIV infection research [1].
价 格：￥电议型 号：T78925产 地：中国大陆
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T78749HIV-1 inhibitor-57；化合物 HIV-1 inhibitor-57HIV-1 inhibitor-57
HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficacy by forming supplementary interactions with residues surrounding the binding site in the HIV-1 reverse transcriptase (RT) [1].
价 格：￥电议型 号：T78749产 地：中国大陆
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T752015’-O-DMTr-5-MedC (Ac)-methyl phosphonamidite；化合物 5’-O-DMTr-5-MedC (Ac)-methyl phosphonamidite5’-O-DM
5’-O-DMTr-5-MedC (Ac)-methyl phosphonamidite, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibiting DNA synthesis and inducing apoptosis, among others [1].
价 格：￥电议型 号：T75201产 地：中国大陆
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T75025ChoKα inhibitor-5；化合物 ChoKα inhibitor-5ChoKα inhibitor-5
ChoKα Inhibitor-5, a sulfur-containing choline kinase inhibitor, effectively inhibits HChoKα1 with an IC50 value of 0.64 μM and induces apoptosis. It is utilized in cancer research [1].
价 格：￥电议型 号：T75025产 地：中国大陆
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T74851PROTAC CDK9 degrader-5；化合物 PROTAC CDK9 degrader-5PROTAC CDK9 degrader-5
PROTAC CDK9 degrader-5 is a selective PROTAC that mediates degradation of CDK9 via the proteasome pathway. It efficiently degrades the CDK9 42 and CDK9 55 isoforms with DC50 values of 0.10 μM and 0.14 μM, respectively [1].
价 格：￥电议型 号：T74851产 地：中国大陆
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T74804HIF-1 inhibitor-5；化合物 HIF-1 inhibitor-5HIF-1 inhibitor-5
HIF-1 inhibitor-5 (Compound 16e) is a potent inhibitor of HIF-1, exhibiting an IC50 value of 2.38 μM and demonstrating significant anti-angiogenic potential [1].
价 格：￥电议型 号：T74804产 地：中国大陆
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T74718STING modulator-5；化合物 STING modulator-5STING modulator-5
STING modulator-5 (compound 38), a STING modulator, exhibits a pIC50 value of 9.5 and antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. Additionally, it acts as an antagonist of THP-1 cells, making it applicable in immunological disease research [1].
价 格：￥电议型 号：T74718产 地：中国大陆
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T7417Avatrombopag；化合物AvatrombopagYM477|||AKR-501|||E5501；YM477|||AKR-501|||1-[3-氯-5-[[[4-(4-氯-2-噻吩基)-5-(4
Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
价 格：￥电议型 号：T7417产 地：中国大陆
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T72568HIV-1 inhibitor-53；化合物 HIV-1 inhibitor-53HIV-1 inhibitor-53
HIV-1 Inhibitor-53 is a dual inhibitor targeting both the HIV-1 protease (PR) with an IC50 value of 1.93 nM and reverse transcriptase (RT) with an IC50 of 2.35 μM. It serves as a potent agent for AIDS research [1].
价 格：￥电议型 号：T72568产 地：中国大陆
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T72566HIV-1 inhibitor-50；化合物 HIV-1 inhibitor-50HIV-1 inhibitor-50
HIV-1 inhibitor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (IC50 = 50 nM). HIV-1 inhibitor-50 shows significant antiviral activity, with EC50s of 2.22-53.3nM against HIV-1 IIIB and its mutant strains.
价 格：￥电议型 号：T72566产 地：中国大陆
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T72565HIV-1 inhibitor-52；化合物 HIV-1 inhibitor-52HIV-1 inhibitor-52
HIV-1 inhibitor-52 is a powerful inhibitor of a broad spectrum of HIV-1 activities, demonstrating effectiveness with EC50 values ranging from 1.6 nM to 6.4 nM against various strains, including WT HIV-1, HIV-1 V370A, HIV-1 ΔV370, HIV-1 V362I/V370A, HIV-1 T332S/V362I/prR41G, HIV-1 A326T/V362I/V370A, and HIV-1 R361K/V362I/L363M.
价 格：￥电议型 号：T72565产 地：中国大陆
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T72408PI3K/mTOR Inhibitor-5；化合物 PI3K/mTOR Inhibitor-5PI3K/mTOR Inhibitor-5
PI3K/mTOR Inhibitor-5 is a potent dual inhibitor of PI3K and mTOR, displaying IC50 values of 86.9 nM (for PI3K) and 14.6 nM (for mTOR), respectively.
价 格：￥电议型 号：T72408产 地：中国大陆
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T71590AHR-5645B fumarate；化合物 AHR-5645B fumarateAHR-5645B fumarate
AHR-5645B fumarate is a substituted benzamide that has been shown to inhibit 3H-spiperone binding to bovine anterior pituitary membranes.
价 格：￥电议型 号：T71590产 地：中国大陆
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T71053AHR-5333 mandelate；化合物 AHR-5333 mandelateAHR-5333 mandelate
AHR-5333 mandelate is an anti-allergy compound which has been shown to protect against antigen-induced anaphylactic collapse and ascaris antigen-induced skin hypersensitivity. AHR-5333 mandelate has also been shown to inhibit 5-HETE, LTB4 and LTC4 synthesis.
价 格：￥电议型 号：T71053产 地：中国大陆
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T69174AHR-5645B free base；化合物 AHR-5645B free baseAHR-5645B free base
AHR-5645B free base is a substituted benzamide which has been shown to inhibit 3H-spiperone binding to bovine anterior pituitary membranes.
价 格：￥电议型 号：T69174产 地：中国大陆
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T68983HR-546；化合物 HR-546HR-546
HR-546 is a prostaglandin E2 and prostaglandin F2alpha antagonist.
价 格：￥电议型 号：T68983产 地：中国大陆
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T67833HIV-1 inhibitor-54；HIV-1 抑制剂54HIV-1 inhibitor-54
HIV-1 inhibitor-54 is a potent HIV-1 inhibitor showing anti-HIV activity (EC50 : 32 nM) against WT HIV-1 (strain IIIB) x in MT-4 cells.HIV-1 inhibitor-54 can be used to study viral infections.
价 格：￥电议型 号：T67833产 地：中国大陆
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T6467Cardioxane；右雷佐生盐酸盐ADR-529 Hydrochloride|||ICRF-187 hydrochloride|||ADR-529|||Dexrazoxane HCl|||Cardi
Cardioxane (ADR-529) is a cardio-protective drug.
价 格：￥电议型 号：T6467产 地：中国大陆
