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T70640SCR1693;化合物 SCR1693SCR1693
SCR1693 is a dual acetylcholinesterase inhibitor (AChEI) and a calcium channel blocker (CCB).
价 格:¥电议型 号:T70640产 地:中国大陆
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T4173R162;化合物R162R162
R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.
价 格:¥电议型 号:T4173产 地:中国大陆
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T39960SHR168442SHR168442SHR168442
SHR168442 is a potent RORγ modulator, exhibiting an IC50 value of 0.035 μM.
价 格:¥电议型 号:T39960产 地:中国大陆
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T32892LR 16;化合物 T32892LR16|||LR-16;LR16|||LR-16
LR 16 has potent effects on oxygen affinity of hemoglobin, on blood cholesterol and on low density lipoprotein.
价 格:¥电议型 号:T32892产 地:中国大陆
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T31364Dehydelone;化合物 T31364KOS1584|||SK-10088|||KOS-1584|||R-1645|||SK10088|||R1645;KOS1584|||SK-10088|||K
Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.
价 格:¥电议型 号:T31364产 地:中国大陆
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T29749AHR-16329;化合物 T29749AHR16329;AHR16329
AHR-16329 can be used in ocular pharmacology.
价 格:¥电议型 号:T29749产 地:中国大陆
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T28491R-1663;化合物 T28491R1663;R1663
R-1663 is a factor Xa inhibitor. R-1663 prolonged clotting times, inhibited thrombin generation (peak height and endogenous thrombin potential [ETP]) and anti-factor Xa activity in a concentration-dependent manner without increasing bleeding time. Pharmacodynamic parameters were strongly correlated to R-1663 plasma concentrations. The inhibition was more pronounced on peak height (IC?? = 194 ng/ml) than on ETP (2790 ng/ml).
价 格:¥电议型 号:T28491产 地:中国大陆
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T27372FR-168888 mesylate;化合物 T27372FR-168888|||FR-168888 Free Base|||FR168888|||FR 168888;FR-168888|||FR-1
FR-168888, a new Na+/H+ exchange inhibitor, can protect the heart from arrhythmia and myocardial cell death in ischemic and reperfused situations.
价 格:¥电议型 号:T27372产 地:中国大陆
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T27371FR-167356;化合物FR-167356FR167356|||FR 167356;FR167356|||FR 167356
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H?-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells.
价 格:¥电议型 号:T27371产 地:中国大陆
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T26736Balapiravir hydrochloride;化合物 T26736R 1626|||Balapiravir HCl|||RO-4588161|||RO4588161|||R-1626|||R16
Balapiravir HCl, an NS5B inhibitor, is used potentially for the treatment of HCV infection.
价 格:¥电议型 号:T26736产 地:中国大陆
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T2551Etravirine;依曲韦林TMC125|||R165335;TMC125|||依曲韦林|||R165335
Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT.
价 格:¥电议型 号:T2551产 地:中国大陆
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T24827SR 16832;化合物SR 16832SR-16832|||SR16832;SR-16832|||SR16832
SR 16832 is a dual-site PPARγ inhibitor. It also inhibits the binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonist GW 9662 and T 0070907.
价 格:¥电议型 号:T24827产 地:中国大陆
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T23389SR1664;化合物SR 1664SR 1664;SR 1664
SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPARγ agonist activity.
价 格:¥电议型 号:T23389产 地:中国大陆
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T15347FR167344 free base;化合物 T15347FR167344 free base
FR167344 free base is an orally active and nonpeptide antagonist of bradykinin receptor B2. FR167344 free base displays a high-affinity binding to the B2 receptor (IC50: 65 nM). It has no binding affinity for the B1 receptor.
价 格:¥电议型 号:T15347产 地:中国大陆
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T14493Balapiravir化合物 T14493R1626|||Ro 4588161
Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (most often for lymphopenia) and the percentage of patients with serious adverse events (especially hematological, infection, ocular events) was dose related. Balapiravir (R1626) is the tri-isobutyrate ester prodrug of R1479 under clinical develop
价 格:¥电议型 号:T14493产 地:中国大陆
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T12904SHR1653;化合物 T12904SHR1653
SHR1653 is a highly potent, selective and brain penetrated antagonist of oxytocin receptor (OTR)(IC50 of 15 nM for hOTR).
价 格:¥电议型 号:T12904产 地:中国大陆
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Fr167454-Hydroxybenzyl cyanide对羟基苯乙腈4-Hydroxyphenylacetonitrile|||对羟基苯乙腈
4-Hydroxybenzyl cyanide (4-Hydroxyphenylacetonitrile) shows strong antioxidative activity.
价 格:¥电议型 号:Fr16745产 地:中国大陆
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Fr16741Oxindole2-吲哚酮2-吲哚酮|||板蓝根|||Indolin-2-one
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.
价 格:¥电议型 号:Fr16741产 地:中国大陆
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Fr166832,6-Dihydroxyacetophenone;化合物 Fr166832,6-Dihydroxyacetophenone
Compound Fr16683 is a natural product for research related to life sciences. The catalog number is Fr16683 and the CAS number is 699-83-2.
价 格:¥电议型 号:Fr16683产 地:中国大陆
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Fr16664Benzothiazolone;化合物 Fr166642-Benzothiazolol;2-Benzothiazolol
Compound Fr16664 is a natural product for research related to life sciences. The catalog number is Fr16664 and the CAS number is 934-34-9.
价 格:¥电议型 号:Fr16664产 地:中国大陆