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已选条件
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T74572RIPK2-IN-2;化合物 RIPK2-IN-2RIPK2-IN-2
RIPK2-IN-2 (example 25) is a RIP2 kinase PROTAC inhibitor that effectively blocks RIP2-dependent proinflammatory signaling and regulates RIP2 kinase activity in autoinflammatory diseases [1].
价 格:¥电议型 号:T74572产 地:中国大陆
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T64064RIPK1-IN-10;化合物 RIPK1-IN-10RIPK1-IN-10
RIPK1-IN-10 is a potent inhibitor of RIPK1.
价 格:¥电议型 号:T64064产 地:中国大陆
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T63544RIPK3-IN-1;RIPK3 抑制剂 1RIPK3-IN-1
RIPK3-IN-1 is a selective and potent RIPK3 inhibitor (IC50: 9.1 nM) that inhibits the activities of c-Met kinase, RIPK1 and RIPK2.RIPK3-IN-1 has potential tumorigenic activity and can be used to study apoptosis.
价 格:¥电议型 号:T63544产 地:中国大陆
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T63469RIPK1-IN-8;化合物 RIPK1-IN-8RIPK1-IN-8
RIPK1-IN-8 is an aminoimidazolopyridine and is a selective and potent inhibitor of RIPK1 (IC50: 4 nM).RIPK1-IN-8 has research potential in inflammatory diseases.
价 格:¥电议型 号:T63469产 地:中国大陆
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T63055RIPK1-IN-9;化合物RIPK1-IN-9RIPK1-IN-9
RIPK1-IN-9 is a potent and selective inhibitor of RIPK1, a dihydronaphthone compound, which inhibits U937 and L929 cells with an IC50 of 2 nM and 1.3 nM, respectively.
价 格:¥电议型 号:T63055产 地:中国大陆
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T62783RIPK2-IN-1;化合物 RIPK2-IN-1RIPK2-IN-1
RIPK2-IN-1 (compound 18f) is a potent inhibitor of RIPK2 (IC50: 51 nM) and also inhibits ALK2 (IC50: 5 nM).
价 格:¥电议型 号:T62783产 地:中国大陆
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T62762RIPK1-IN-11;化合物 RIPK1-IN-11RIPK1-IN-11
RIPK1-IN-11 is an orally active RIPK1 inhibitor with a Kd value of 9.2 nM and an IC50 value of 67 nM. RIPK1-IN-11 inhibits necrosis in human and mouse cells and exhibits anti-inflammatory effects.
价 格:¥电议型 号:T62762产 地:中国大陆
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T62723RIPK1-IN-12;化合物 RIPK1-IN-12RIPK1-IN-12
RIPK1-IN-12 is a potent inhibitor of RIPK1, which exhibits an inhibitory effect on necroptosis in human and mouse cells with EC50 values of 1.6 and 2.9 nM, respectively.
价 格:¥电议型 号:T62723产 地:中国大陆
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T62569RIPK3-IN-2;化合物 RIPK3-IN-2RIPK3-IN-2
RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.
价 格:¥电议型 号:T62569产 地:中国大陆
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T62499RIPK1-IN-14;化合物 RIPK1-IN-14RIPK1-IN-14
RIPK1-IN-14 (Compound 41) is a potent inhibitor of RIPK1 (IC50: 92 nM).RIPK1-IN-14 has a significant anti-necrotic apoptotic effect in a model of necrotic apoptosis in U937 cells.
价 格:¥电议型 号:T62499产 地:中国大陆
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T61887RIPK1-IN-13;化合物 RIPK1-IN-13RIPK1-IN-13
RIPK1-IN-13 (Compound 8) is an effective RIPK1 inhibitor (IC50=1139 nM). By inhibiting RIPK1, RIPK1-IN-13 can block the activation of necrotic apoptosis pathway. RIPK1-IN-13 has research potential in inflammatory diseases.
价 格:¥电议型 号:T61887产 地:中国大陆
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T60862RIPK1-IN-15;化合物 RIPK1-IN-15RIPK1-IN-15
RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].
价 格:¥电议型 号:T60862产 地:中国大陆
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T5401GSK2983559 active metabolite;化合物GSK2983559GSK2983559|||RIPK2 inhibitor 1|||RIPK2-IN-1;GSK2983559|||R
GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.
价 格:¥电议型 号:T5401产 地:中国大陆
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T36243PROTAC RIPK degrader-6;PROTAC RIPK degrader-6PROTAC RIPK degrader-6
PROTAC RIPK degrader-6 (example 1) is a PROTAC designed for the targeted degradation of RIP Kinase, featuring a RIP2 kinase inhibitor connected through a linker to a cereblon binder[1].
价 格:¥电议型 号:T36243产 地:中国大陆
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T16755RIPK-IN-4;化合物 T16755RIPK-IN-4
RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability (IC50: 3 nM).
价 格:¥电议型 号:T16755产 地:中国大陆
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T13846PROTAC RIPK degrader-2;化合物 T13846PROTAC RIPK degrader-2
PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation.
价 格:¥电议型 号:T13846产 地:中国大陆
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T12731RIPK1-IN-7;化合物RIPK1-IN-7RIPK1-IN-7
RIPK1-IN-7 is a potent and selective inhibitor of RIPK1(Kd of 4 nM and an enzymatic IC50 of 11 nM),andexhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.
价 格:¥电议型 号:T12731产 地:中国大陆
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T12730RIPK1-IN-4;化合物RIPK1-IN-4RIPK1-IN-4
RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase).
价 格:¥电议型 号:T12730产 地:中国大陆
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T12729RIPK1-IN-3;化合物 T12729RIPK1-IN-3
RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.
价 格:¥电议型 号:T12729产 地:中国大陆