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  • T3465Vesnarinone维司力农；Piteranometozine；OPC-8212；Arkin

    Vesnarinone (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by in

    价 格：￥电议型 号：T3465产 地：中国大陆

  • T2414TorkinibPP 242

    Torkinib (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).

    价 格：￥电议型 号：T2414产 地：中国大陆

  • T2011RKI1313RKI-1313；RKI 1313

    RKI-1313 was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion.

    价 格：￥电议型 号：T2011产 地：中国大陆

  • T1898RKI-1447RKI1447；RKI 1447

    RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.

    价 格：￥电议型 号：T1898产 地：中国大陆

  • T1362Hypoxanthine6-羟基嘌呤；Sarkin；Purin-6-ol；6-Hydroxypurine；Sarcine

    Hypoxanthine, a purine derivative, is a potential free radical generator. It has been used in studies as in indicator, along with uric acid and allantoin, of in vivo free radical reactions.

    价 格：￥电议型 号：T1362产 地：中国大陆

  • T11224RineterkibERK-IN-1

    Rineterkib is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.

    价 格：￥电议型 号：T11224产 地：中国大陆

  • T10429TizaterkibAZD-0364

    AZD-0364 is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1 (example 18; IC50: 0.6 nM).

    价 格：￥电议型 号：T10429产 地：中国大陆

  • T11758KI696 isomerKI696 isomer

    KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 isomer is the less active isomer of KI696 .

    价 格：￥电议型 号：T11758产 地：美洲

  • T1898RKI-1447RKI-1447,RKI1447,RKI 1447

    RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.

    价 格：￥电议型 号：T1898产 地：美洲

  • T2011RKI-1313RKI-1313,RKI1313,RKI 1313

    RKI-1313 was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion.

    价 格：￥电议型 号：T2011产 地：美洲

  • T2414TorkinibTorkinib,PP 242,

    Torkinib (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).

    价 格：￥电议型 号：T2414产 地：美洲

  • T7626LBudipine Hydrochloride；化合物 T7626LBY-701|||BY 701|||BY701|||Parkinsan；BY-701|||BY 701|||BY701|||Parki

    Budipine is a non-dopaminergic antiparkinsonian drug. The primary action of budipine is an indirect dopaminergic effect as shown by facilitation of dopamine (DA) release, inhibition of monoamine oxidase type B (MAO-B) and of DA (re) up-take and stimulation of aromatic L-amino acid decarboxylase (AADC).

    价 格：￥电议型 号：T7626L产 地：中国大陆

  • T61905RKI-1447 dihydrochloride；化合物 RKI-1447 dihydrochlorideRKI-1447 dihydrochloride

    RKI 1447 dihydrochloride is an effective and selective ROCK inhibitor (ROCK1 IC50=14.5 nM, ROCK2 IC50=6.2 nM). RKI 1447 dihydrochloride can inhibit the growth of colorectal cancer cells and promote cell apoptosis.

    价 格：￥电议型 号：T61905产 地：中国大陆

  • T4091Temuterkib；化合物LY3214996LY3214996；LY3214996

    Temuterkib (LY3214996) is a potent and selective, orally available inhibitor of the extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity.

    价 格：￥电议型 号：T4091产 地：中国大陆

  • T39159Edaxeterkib；EdaxeterkibEdaxeterkib

    Edaxeterkib is a potent extracellular signal- regulated kinase (ERK) inhibitor for the research of cancer.

    价 格：￥电议型 号：T39159产 地：中国大陆

  • T36676Rineterkib hydrochloride；Rineterkib hydrochlorideRineterkib hydrochloride

    Rineterkib hydrochloride (compound B) is an orally active RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer[1].

    价 格：￥电议型 号：T36676产 地：中国大陆

  • T35863VRK-IN-1VRK 抑制剂1VRK IN 1|||VRKIN1

    VRK-IN-1 is a potent and selective inhibitor of cowpox-associated kinase 1 (VRK1), which can be used in the study of neurological disorders.

    价 格：￥电议型 号：T35863产 地：中国大陆

  • T3465Vesnarinone维司力农维司力农|||OPC-8212|||Arkin|||Piteranometozine

    Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.

    价 格：￥电议型 号：T3465产 地：中国大陆

  • T27534Herkinorin；化合物 T27534BF3DNCA methyl ester；BF3DNCA methyl ester

    Herkinorin is an opioid analgesic and an analogue of the natural product Salvinorin A. herkinorin is a μ-opioid agonist with more than 100x higher μ-opioid affinity and 50x lower κ-opioid affinity compared to Salvinorin A. Herkinorin is a semi-synthetic compound, made from Salvinorin B, which is most conveniently made from Salvinorin A by deacetylation, as while both Salvinorin A and Salvinorin B are found in the plant Salvia divinorum, Salvinorin A is present in larger quantities.

    价 格：￥电议型 号：T27534产 地：中国大陆

  • T27226DYRKi；化合物 T27226DYRKi

    DYRKi is a nontoxic, DYRK1-selective inhibitor.

    价 格：￥电议型 号：T27226产 地：中国大陆

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