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T79645Tubulin polymerization-IN-48;化合物 Tubulin polymerization-IN-48Tubulin polymerization-IN-48
Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network. It impedes the proliferation of neuroblastoma cancer cells, exhibiting IC50 values of 79 nM and 165 nM for the Chp-134 and Kelly cell lines, respectively [1].
价 格:¥电议型 号:T79645产 地:中国大陆
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T79629Tubulin polymerization-IN-46;化合物 Tubulin polymerization-IN-46Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast cancer cells in the G2/M phase, exhibiting potent anti-proliferative activity with an IC50 of 10 nM [1].
价 格:¥电议型 号:T79629产 地:中国大陆
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T79532Tubulin polymerization-IN-44;化合物 Tubulin polymerization-IN-44Tubulin polymerization-IN-44
Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it useful for cancer research.
价 格:¥电议型 号:T79532产 地:中国大陆
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T79452Tubulin/HDAC-IN-2;化合物 Tubulin/HDAC-IN-2Tubulin/HDAC-IN-2
Tubulin/HDAC-IN-2 (Compound II-19k) is a dual inhibitor targeting Tubulin and HDAC, exhibiting IC50 values of 0.403 μM for HDAC1, 0.591 μM for HDAC2, 3.552 μM for HDAC3, and 0.459 μM for HDAC6. The compound induces G2 phase cell cycle arrest and promotes apoptosis. It effectively hampers the proliferation of both hematoma and solid tumor cells, diminishes tumor metastasis, and demonstrates tumor growth inhibition in a liver tumor allograft mouse model [1].
价 格:¥电议型 号:T79452产 地:中国大陆
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T79429Tubulin polymerization-IN-50;化合物 Tubulin polymerization-IN-50Tubulin polymerization-IN-50
Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell cycle arrest at the G2/M phase [1].
价 格:¥电议型 号:T79429产 地:中国大陆
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T79341Tubulin polymerization-IN-45;化合物 Tubulin polymerization-IN-45Tubulin polymerization-IN-45
Tubulin polymerization-IN-45, a tubulin-targeting agent, acts as a tubulin polymerization inhibitor by binding to the tubulin´s colchicine site. It induces apoptotic cell death in hepatocellular cancer (HCC) cells [1].
价 格:¥电议型 号:T79341产 地:中国大陆
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T79268Tubulin polymerization-IN-42;化合物 Tubulin polymerization-IN-42Tubulin polymerization-IN-42
Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].
价 格:¥电议型 号:T79268产 地:中国大陆
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T79214Tubulin/AKT1-IN-1;化合物 Tubulin/AKT1-IN-1Tubulin/AKT1-IN-1
Tubulin/AKT1-IN-1 (Compound D1-1) serves as an inhibitor of both tubulin polymerization and AKT pathway activation, effectively suppressing proliferation and metastasis of H1975 cells while modestly inducing apoptosis. This compound is utilized in the study of non-small-cell lung cancer (NSCLC) [1].
价 格:¥电议型 号:T79214产 地:中国大陆
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T78917Tubulin inhibitor 33;化合物 Tubulin inhibitor 33Tubulin inhibitor 33
Tubulin Inhibitor 33 is a dose-dependent inhibitor of tubulin polymerization, exhibiting an IC50 value of 9.05 μM. This compound demonstrates antitumor activity and induces apoptosis, making it useful for antitumor research [1].
价 格:¥电议型 号:T78917产 地:中国大陆
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T78880Tubulin/HDAC-IN-3;化合物 Tubulin/HDAC-IN-3Tubulin/HDAC-IN-3
Tubulin/HDAC-IN-3 (compound 12a) serves as a potent dual inhibitor of tubulin polymerization and HDAC1/8, exhibiting IC50 values of 5.4 μM for tubulin polymerization, and 0.155 and 0.177 μM for HDAC1 and HDAC8, respectively. Its mechanism of action includes obstructing the cell cycle, triggering apoptosis, and suppressing colony formation [1].
价 格:¥电议型 号:T78880产 地:中国大陆
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T78773Tubulin inhibitor 38;化合物 Tubulin inhibitor 38Tubulin inhibitor 38
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell cycle at the G2/M phase, ultimately triggering apoptosis. Administered at 100 nM for 24 hours, it shows considerable cytotoxicity and selectivity within HeLa, MCF7, and U87 MG cell lines [1].
价 格:¥电议型 号:T78773产 地:中国大陆
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T78772Tubulin inhibitor 37;化合物 Tubulin inhibitor 37Tubulin inhibitor 37
Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 ?M) and demonstrates antiproliferative activity against human tumor cell lines, showing promise for cancer research [1].
价 格:¥电议型 号:T78772产 地:中国大陆
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T78771Tubulin inhibitor 36;化合物 Tubulin inhibitor 36Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells, reflected by an IC50 value of 1.5±0.1 μM. Exhibiting significant anti-mitotic activity, this compound demonstrates anti-tumor potential, particularly useful in glioblastoma multiforme (GBM) research [1].
价 格:¥电议型 号:T78771产 地:中国大陆
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T78761Tubulin inhibitor 34;化合物 Tubulin inhibitor 34Tubulin inhibitor 34
Tubulin Inhibitor 34 (compound b5), a potent anticancer agent, inhibits tubulin polymerization and induces G2/M arrest and apoptosis. The compound demonstrates significant antivascular and antitumor activity [1].
价 格:¥电议型 号:T78761产 地:中国大陆
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T78701Tubulin inhibitor 32;Tubulin 抑制剂32Tubulin inhibitor 32
Tubulin inhibitor 32 is an orally active novel microtubule inhibitor with antiproliferative and antitumor activity, inhibits microtubule polymerization, induces apoptosis and cell cycle arrest in G2/M phase.
价 格:¥电议型 号:T78701产 地:中国大陆
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T77728Tubulin polymerization-IN-55;Tubulin polymerization 抑制剂55Tubulin polymerization-IN-55
Tubulin polymerization-IN-55 is a potent Tubulin Polymerization inhibitor with potential anti-angiogenic and anti-tumour activity, showing anti-proliferative effects against A549, K562, HepG2, MDA-MB-231 and HFL-1.
价 格:¥电议型 号:T77728产 地:中国大陆
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T77651Tubulin polymerization-IN-47;Tubulin聚合物抑制剂47Tubulin polymerization-IN-47
Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 and Kelly cell lines, respectively. Tubulin polymerization-IN-47 is a candidate compound for the treatment of hepatocellular carcinoma, colon cancer, lung cancer and breast cancer.
价 格:¥电议型 号:T77651产 地:中国大陆
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T77647Tubulin polymerization-IN-43;Tubulin polymerization抑制剂43Tubulin polymerization-IN-43
Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.Tubulin polymerization-IN-43 has multiple effects, disrupting the cellular microtubule network by targeting the colchicine locus and promoting cell cycle arrest and apoptosis in leukaemia cells. Tubulin polymerisation-IN-43 has multiple effects, promoting leukaemia cell cycle arrest in G2/M phase and apoptosis by targeting Colchicine sites to disrupt the cellular microtubule network.
价 格:¥电议型 号:T77647产 地:中国大陆
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T77584Tubulin inhibitor 35;Tubulin抑制剂35Tubulin IN 35;Tubulin IN 35
Tubulin inhibitor 35 (Tubulin IN 35) is a potent dual inhibitor of topoisomerase I and microtubule protein polymerization with antitumor activity, inhibits migration and invasion of MGC-803 and RKO cell lines, interrupts the cell cycle and induces apoptosis.
价 格:¥电议型 号:T77584产 地:中国大陆
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T75383Anti-α-Tubulin Antibody, AF555 conjugate;化合物 Anti-α-Tubulin Antibody, AF555 conjugateAnti-α-Tubulin
Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for the specific detection of tubulin (Ex/Em: 554/567 nm) [1].
价 格:¥电议型 号:T75383产 地:中国大陆