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T75481-Methylguanosine1-Methylguanosine,1 Methylguanosine,Endogenous Metabolite,Inhibitor,inhibit,1Methyl
1-Methylguanosine is a methylated nucleoside. It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patients with malignant tumors.
价 格:¥电议型 号:T7548产 地:中国大陆
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T63536Dual FAAH/sEH-IN-1
Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
价 格:¥电议型 号:T63536产 地:中国大陆
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T6522Guanabenz AcetateAdrenergic Receptor,Guanabenz Acetate,Wy 8678,Guanabenz,Beta Receptor,Wy8678,BR 750
Guanabenz Acetate is a specific agonist of adrenergic receptor. The pEC50 for α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor is 8.25, 7.01 and ~5, respectively.
价 格:¥电议型 号:T6522产 地:中国大陆
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T7423Diquafosol tetrasodiumInhibitor,inhibit,INS-365,Diquafosol tetrasodium,INS 365,P2Y Receptor
Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium improves tear film stability and visual function, as a topical treatment of dry eye disease.
价 格:¥电议型 号:T7423产 地:中国大陆
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T7116Sodium gualenateSodium gualenate,Inhibitor,inhibit,Guaiazulenesulfonate
Sodium gualenate (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects.
价 格:¥电议型 号:T7116产 地:中国大陆
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T40187GNF2133β-cell,RIP-DTA mice,Inhibitor,insulin secretion,GNF2133,inhibit,Dual specificity tyrosine reg
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.
价 格:¥电议型 号:T40187产 地:中国大陆
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TQ0193N2,N2-DimethylguanosineN-2,N2-Dimethylguanosine,N2,N2-Dimethylguanosine,inhibit,Inhibitor,N2,N2Dimet
N2,N2-Dimethylguanosine is an urinary nucleoside. The mean levels of urinary N2,N2-Dimethylguanosine in patients with colorectal cancer are significantly higher than those in patients with intestinal villous adenoma or healthy adults.
价 格:¥电议型 号:TQ0193产 地:中国大陆
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T9080PlecanatideInhibitor,Guanylate Cyclase,chronic,inhibit,anti-inflammatory,Plecanatide,idiopathic,GC-C
Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.
价 格:¥电议型 号:T9080产 地:中国大陆
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T8182LGuan-fu base A hydrochloride(1394-48-5 free base)Guanfu base A hydrochloride(1394485 free base),Guan
Guan-fu base A hydrochloride is an antiarrhythmic alkaloid was isolated from Aconitum coreanum. Guanfu base A is hydrochloride a CYP2D6 inhibitor of human, monkey, and dog isoforms.
价 格:¥电议型 号:T8182L产 地:中国大陆
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T9174IcerguastatIFB 088,Sephin1,Inhibitor,misfolding,Sephin-1,prion,Icerguastat,IFB088,stress,eIF2α,scler
Sephin1 is a selective inhibitor of holophosphatase. Sephin1 safely and selectively inhibited a regulatory subunit of protein phosphatase 1 in vivo.
价 格:¥电议型 号:T9174产 地:中国大陆
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T7323BCI-215specificity,Phosphatase,DUSP-MKP,inhibit,Inhibitor,MAPK,BCI-215,BCI215,BCI 215,dual
BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling
价 格:¥电议型 号:T7323产 地:中国大陆
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T9698UC2288Attenuator,786-O,Inhibitor,UC-2288,MDM-2/p53,inhibit,UC2288,ovarian,RCC,HK2,UC 2288,p21,sorafe
UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability.
价 格:¥电议型 号:T9698产 地:中国大陆
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T77823’-Deoxyguanosine3’Deoxyguanosine,3’ Deoxyguanosine
3´-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.
价 格:¥电议型 号:T7782产 地:中国大陆
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T6968RiociguatInhibitor,inhibit,BAY-632521,Riociguat,Guanylate Cyclase,BAY632521
Riociguat is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.
价 格:¥电议型 号:T6968产 地:中国大陆
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TNU01573’-O-Methyl guanosine
Nucleoside Derivatives –3’-Modified nucleoside
价 格:¥电议型 号:TNU0157产 地:中国大陆
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T7514N2-MethylguanosineN2-Methylguanosine,inhibit,Nucleoside Antimetabolite/Analog,N-2-Methylguanosine,In
N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA´s
价 格:¥电议型 号:T7514产 地:中国大陆
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T4039BIBB 515BIBB 515,Inhibitor,OSC,inhibit,cyclase,effect,metabolism,LDL,BIBB-515,2,3-oxidosqualene,BIBB
BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2, 3-oxidosqualene to lanosterol, a precursor to cholesterol, in mammals and fungi. Total cholesterol was reduced by 19% in normolipemic hamsters at a dose of 55 mg/kg/day for 11 days and 25% in hyperlipemic
价 格:¥电议型 号:T4039产 地:中国大陆
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T7539O6-Benzylguaninepancreatic,DNA/RNA Synthesis,transcriptional,PARP1,p53,inhibit,cyclin,O-6-Benzylguan
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
价 格:¥电议型 号:T7539产 地:中国大陆
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TN2237Steviol-?19-?O-?glucosiderebuadiana,Stevia,Steviol ?19 ?O ?glucoside,Steviol?19?O?glucoside,Inhibito
Steviol-?19-?O-?glucoside is a natural product from the steviol glycosides biosynthesis pathway in Stevia rebuadiana.
价 格:¥电议型 号:TN2237产 地:中国大陆
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T9002squarunkinAsquarunkinA
squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-terminus of Src kinase to UNC119A
价 格:¥电议型 号:T9002产 地:中国大陆