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T63947GRPR antagonist-1；化合物 GRPR antagonist-1GRPR antagonist-1
GRPR antagonist-1 is a potent antagonist of the gastrin-releasing peptide receptor (GRPR) and is cytotoxic to certain cancer cells (able to act on PC3 cells (IC50: 4.97 μM), Pan02 cells (IC50: 4.36 μM), HGC-27 cells (IC50: 3.40 μM)). antagonist-1 was able to reduce the level of Bcl-2 and increase the level of Bax, thereby inhibiting the viability of HGC-27 cells and causing apoptosis, and exhibited anti-cancer effects.
价 格：￥电议型 号：T63947产 地：中国大陆
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T63578Mrgx2 antagonist-1；化合物 Mrgx2 antagonist-1Mrgx2 antagonist-1
Mrgx2 antagonist-1 is a potent antagonist of Mrgx2 (Mas-related Gene X2) and can be used to study Mrgx2-mediated diseases and disorders.
价 格：￥电议型 号：T63578产 地：中国大陆
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T62641EP2 receptor antagonist-1；化合物 EP2 receptor antagonist-1EP2 receptor antagonist-1
EP2 receptor antagonist-1 is a reversible, potent, agonist-dependent variant of the prostaglandin EP2 receptor antagonist.EP2 receptor antagonist-1 exhibits anti-inflammatory activity.
价 格：￥电议型 号：T62641产 地：中国大陆
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T62488P2X7 receptor antagonist-1；化合物 P2X7 receptor antagonist-1P2X7 receptor antagonist-1
P2X7 receptor antagonist-1 is a purinergic P2X7 receptor antagonist with anti-neuroinflammatory effects.
价 格：￥电议型 号：T62488产 地：中国大陆
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T62325CXCR7 antagonist-1 hydrochloride；化合物 CXCR7 antagonist-1 hydrochlorideCXCR7 antagonist-1 hydrochlorid
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of SDF-1 chemokine (also known as CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. hydrochloride can be used for the prevention of tumour cell proliferation, tumour formation, inflammatory diseases and many other diseases.
价 格：￥电议型 号：T62325产 地：中国大陆
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T618375-HT6/5-HT2AR antagonist-1；化合物 5-HT6/5-HT2AR antagonist-15-HT6/5-HT2AR antagonist-1
5-HT6/5-HT2AR antagonist-1 is a powerful and effective compound that acts as a dual antagonist for both the 5-HT6 and 5-HT2A receptors. It exhibits high potency with K i values of 11 nM and 39 nM for the respective receptors [1].
价 格：￥电议型 号：T61837产 地：中国大陆
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T61347D4R antagonist-1；化合物 D4R antagonist-1D4R antagonist-1
D4R Antagonist-1, characterized by its potent and selective antagonistic action against D4 receptors with an IC50 value of 6.87 μM, holds potential for Parkinson’s disease research [1].
价 格：￥电议型 号：T61347产 地：中国大陆
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T61144Hepcidin antagonist-1；Hepcidin 拮抗剂1Hepcidin antagonist-1
Hepcidin antagonist-1 is an iron-modulating antagonist.Hepcidin antagonist-1 can be used to study metabolic disorders such as iron-deficiency diseases and anemia.
价 格：￥电议型 号：T61144产 地：中国大陆
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T61026CaV1.3 antagonist-1；化合物 CaV1.3 antagonist-1CaV1.3 antagonist-1
CaV1.3 antagonist-1 is a cyclopentyl derivative with the potential for the research of Parkinson´s disease. CaV1.3 antagonist-1 inhibits Ca V 1.3 LTCC over 600-fold more effectively than Ca V 1.2 LTCC. CaV1.3 antagonist-1 is a potent and highly selective antagonist of Ca V 1.3 L-type calcium channel (LTCC) with an IC50 value of 1.7 μM [1].
价 格：￥电议型 号：T61026产 地：中国大陆
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T60917Dopamine D4 receptor antagonist-1；化合物 Dopamine D4 receptor antagonist-1Dopamine D4 receptor antagoni
Dopamine D4 receptor antagonist-1 can be used in schizophrenia study. Dopamine D4 receptor antagonist-1 is a selective antagonist of Dopamine D4 receptor (DRD4). The Ki value of Dopamine D4 receptor antagonist-1 for Hd4.2 is 9.0 nM [1].
价 格：￥电议型 号：T60917产 地：中国大陆
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T60732A2A/A1 AR antagonist-1；化合物 A2A/A1?AR antagonist-1A2A/A1 AR antagonist-1
A2A/A1 AR antagonist-1 (compound 1a) has the potential for ischemic stroke research which is potent A 2A /A 1 AR dual antagonist with Ki s of 5.58 and 24.2 nM, respectively [1].
价 格：￥电议型 号：T60732产 地：中国大陆
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T40270MrgprX2 antagonist-1；MrgprX2 antagonist-1MrgprX2 antagonist-1；MrgprX2 antagonist-1
MrgprX2 antagonist-1, is a novel MrgprX2 antagonist compound. It exhibits potential for exploration in studying cutaneous inflammatory disorders.
价 格：￥电议型 号：T40270产 地：中国大陆
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T39078CXCR7 antagonist-1；CXCR7拮抗剂1CXCR7 antagonist-1；CXCR7 antagonist-1
CXCR7 antagonist-1 is a specific antagonist of the binding of the SDF-1 chemokine or I-TAC to the chemokine receptor CXCR7. CXCR7 antagonist-1 prevents tumor cell proliferation and tumor formation and can be used in studies about inflammatory diseases.
价 格：￥电议型 号：T39078产 地：中国大陆
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T38634Histamine H4 receptor antagonist-1；Histamine H4 receptor antagonist-1Histamine H4 receptor antagonis
Histamine H4 receptor antagonist-1 is a potent antagonist of the histamine H4 receptor.
价 格：￥电议型 号：T38634产 地：中国大陆
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T36744CDK9 Antagonist-1；CDK9 Antagonist-1CDK9 Antagonist-1；CDK9 Antagonist-1
CDK9 Antagonist-1 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1].
价 格：￥电议型 号：T36744产 地：中国大陆
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T36036CAY10786；化合物CAY10786GPR52 antagonist-1；GPR52 antagonist-1
CAY10786 (GPR52 antagonist-1) is an antagonist of G protein-coupled receptor 52 (GPR52, IC50 = 0.63 μM).
价 格：￥电议型 号：T36036产 地：中国大陆
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T11230ERRα antagonist-1；化合物ERRα 拮抗剂-1ERR+/- antagonist-1|||ERRa antagonist-1；ERR+/- antagonist-1|||ERRa an
ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, displaying IC50 values of 170 nM and 180 nM, respectively. Notably, ERRα antagonist-1 does not interfere with the interactions involving ERRβ or ERRγ and the PGC-1α and PGC-1β coactivators. Furthermore, it does not affect the interaction between ei
价 格：￥电议型 号：T11230产 地：中国大陆
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T11077Dopamine D2 receptor antagonist-1；多巴胺D2受体拮抗剂-1Dopamine D2 receptor antagonist-1
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.
价 格：￥电议型 号：T11077产 地：中国大陆
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T10248Adenosine antagonist-1；腺苷拮抗剂1Adenosine antagonist-1
Adenosine antagonist-1 acts as an adenosine A3 receptor (AA3R) antagonist.
价 格：￥电议型 号：T10248产 地：中国大陆
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T10031EP1-antagonist-1；EP1-拮抗剂-1EP1-antanoist-1|||EP1 antagonist 1；EP1-antanoist-1|||EP1 antagonist 1
EP1-antagonist-1 (EP1 antagonist 1) is an EP1 antagonist (pKi: 7.54; pIC50: 8.5).
价 格：￥电议型 号：T10031产 地：中国大陆
